TY - JOUR
T1 - A Rare Case of 7 Simultaneous Arterial Dissections and Review of The Literature
AU - Amitai Komem, Daphna
AU - Sukenik Halevy, Rivka
AU - Griton, Yigal
AU - Shnaker, Ali
AU - Levy, Yair
AU - Weissmann, Jonathan
AU - Fajer, Simone
N1 - Publisher Copyright:
© The Author(s) 2019.
PY - 2019/10/1
Y1 - 2019/10/1
N2 - Objective: Spontaneous multiple artery dissection is a relatively rare phenomenon. Early clinical signs are often nonspecific, making it difficult to diagnose. Case Report: This is a case of a 51-year-old female who presented with spontaneous dissection of 4 visceral arteries, both iliac arteries, and of the right internal carotid artery. The patient underwent urgent successful endovascular repair. Later complications included acute respiratory distress syndrome and pneumonia after massive blood transfusion. She recovered gradually and was discharged after 21 days. Due to this rare presentation, genetic investigation was performed in search of a connective tissue disorder. Results revealed a new COL3A1 subtype mutation. The pathogenicity of this variant remains unclear. Conclusion: We recommend a high index of suspicion for visceral artery dissection in the differential diagnosis for abdominal pain with concurrent uncontrolled hypertension. Early diagnosis and intervention are crucial to reducing the mortality rate.
AB - Objective: Spontaneous multiple artery dissection is a relatively rare phenomenon. Early clinical signs are often nonspecific, making it difficult to diagnose. Case Report: This is a case of a 51-year-old female who presented with spontaneous dissection of 4 visceral arteries, both iliac arteries, and of the right internal carotid artery. The patient underwent urgent successful endovascular repair. Later complications included acute respiratory distress syndrome and pneumonia after massive blood transfusion. She recovered gradually and was discharged after 21 days. Due to this rare presentation, genetic investigation was performed in search of a connective tissue disorder. Results revealed a new COL3A1 subtype mutation. The pathogenicity of this variant remains unclear. Conclusion: We recommend a high index of suspicion for visceral artery dissection in the differential diagnosis for abdominal pain with concurrent uncontrolled hypertension. Early diagnosis and intervention are crucial to reducing the mortality rate.
KW - dissection
KW - endovascular repair
KW - hypertension
KW - multiple artery dissections
KW - pseudoaneurysm
KW - stent graft
UR - http://www.scopus.com/inward/record.url?scp=85070364218&partnerID=8YFLogxK
U2 - 10.1177/1538574419864783
DO - 10.1177/1538574419864783
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C2 - 31339471
AN - SCOPUS:85070364218
VL - 53
SP - 617
EP - 622
JO - Vascular and Endovascular Surgery
JF - Vascular and Endovascular Surgery
SN - 1538-5744
IS - 7
ER -