TY - JOUR
T1 - A prospective, longitudinal, observational cohort study examining how glaucoma affects quality of life and visually-related function over 4 years
T2 - Design and methodology Glaucoma
AU - Waisbourd, Michael
AU - Parker, Samantha
AU - Ekici, Feyzahan
AU - Martinez, Patricia
AU - Murphy, Rachel
AU - Scully, Katie
AU - Wizov, Sheryl S.
AU - Hark, Lisa A.
AU - Spaeth, George L.
N1 - Publisher Copyright:
© 2015 Waisbourd et al.
PY - 2015/8/1
Y1 - 2015/8/1
N2 - Background: The aim of this study is to summarize the design and methodology of a prospective, longitudinal, observational cohort study to investigate how glaucoma affects patients' quality of life and visually-related function over a 4-year period. Methods/Design: One hundred sixty-one (161) subjects were enrolled in this ongoing study. Patients between the ages of 21-85 years with a minimum 2-year diagnosis of primary open-angle glaucoma, chronic primary angle-closure glaucoma or pseudoexfoliation glaucoma were included. Each patient visited Wills Eye Hospital for a baseline visit. Follow-up is planned for a minimum of 4 years, with annual visits. Each visit includes (1) Clinical evaluation: a slit lamp examination, fundoscopy, intraocular pressure measurement, visual field examination, spectral domain optical coherence tomography, Pelli-Robson Contrast Sensitivity test and the Spaeth-Richman Contrast Sensitivity test; (2) a performance based measure: the Compressed Assessment of Ability Related to Vision; and (3) Subjective measures of vision-related quality of life (the National Eye Institute Visual Functioning Questionnaire 25 and the Modified Glaucoma Symptom Scale). Discussion: The results of this ongoing, prospective, longitudinal study are expected to shed light on the relationships between clinical measures, performance-based measures and subjective measures of well-being, in order to assess changes in the quality of life and the ability to function of patients with glaucoma over time.
AB - Background: The aim of this study is to summarize the design and methodology of a prospective, longitudinal, observational cohort study to investigate how glaucoma affects patients' quality of life and visually-related function over a 4-year period. Methods/Design: One hundred sixty-one (161) subjects were enrolled in this ongoing study. Patients between the ages of 21-85 years with a minimum 2-year diagnosis of primary open-angle glaucoma, chronic primary angle-closure glaucoma or pseudoexfoliation glaucoma were included. Each patient visited Wills Eye Hospital for a baseline visit. Follow-up is planned for a minimum of 4 years, with annual visits. Each visit includes (1) Clinical evaluation: a slit lamp examination, fundoscopy, intraocular pressure measurement, visual field examination, spectral domain optical coherence tomography, Pelli-Robson Contrast Sensitivity test and the Spaeth-Richman Contrast Sensitivity test; (2) a performance based measure: the Compressed Assessment of Ability Related to Vision; and (3) Subjective measures of vision-related quality of life (the National Eye Institute Visual Functioning Questionnaire 25 and the Modified Glaucoma Symptom Scale). Discussion: The results of this ongoing, prospective, longitudinal study are expected to shed light on the relationships between clinical measures, performance-based measures and subjective measures of well-being, in order to assess changes in the quality of life and the ability to function of patients with glaucoma over time.
KW - Glaucoma
KW - Performance-based measures
KW - Vision-related quality of life
UR - http://www.scopus.com/inward/record.url?scp=84938371535&partnerID=8YFLogxK
U2 - 10.1186/s12886-015-0088-x
DO - 10.1186/s12886-015-0088-x
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C2 - 26231376
AN - SCOPUS:84938371535
SN - 1471-2415
VL - 15
JO - BMC Ophthalmology
JF - BMC Ophthalmology
IS - 1
M1 - 91
ER -