A possible relationship between viral infection and hydrarthrosis

M. Yaron, I. Yaron, E. Eylan, O. Smetana, M. Herzberg, U. Zor

Research output: Contribution to journalArticlepeer-review


Addition of poly I:C and interferon to cultures of fibroblasts from rheumatoid and non-rheumatoid human synovial fluid cultures stimulated prostaglandin E synthesis. Stimulation of prostaglandin synthesis was accompanied by increased production of hyaluronic acid and glucose uptake by the cultured synovial fibroblasts. Hydrocortisone inhibited overproduction of prostaglandin E and hyaluronic acid induced by poly I:C. Cultures to which poly I:C was added did not show a cytopathic effect upon addition of vesicular stomatitis virus and interferon was found in such media.

Original languageEnglish
Pages (from-to)171-173+218
Issue number7-8
StatePublished - 1977


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