TY - GEN
T1 - A patient based approach for fluid structure interaction in ruptured abdominal aortic aneurysms
AU - Xenos, Michalis
AU - Rambhia, Suraj
AU - Alemu, Yared
AU - Einav, Shmuel
AU - Ricotta, John J.
AU - Labropoulos, Nicos
AU - Tassiopoulos, Apostolos
AU - Bluestein, Danny
PY - 2009
Y1 - 2009
N2 - Fluid structure interaction (FSI) simulations were conducted to assess the risk of rupture in reconstructed AAA from patients who had contained ruptured AAAs. The goal was to test to ability of our FSI methodology to predict the location of rupture, by correlating the high wall stress regions with the actual rupture location. We also present a parametric study in which the relationship of iliac bifurcation angle and the role of embedded calcifications were studied in respect to the aneurismal wall stress. The patient specific AAA FSI simulations were carried out with advanced constitutive material models of the various components of AAA, including models that describe the wall anisotropy, structural strength based on collagen fibers orientation within the arterial wall, AAA intraluminal thrombus (ILT), and embedded calcifications. The anisotropic material model used to describe the wall properties closely correlated with experimental results of AAA specimens [1]. The results demonstrate that the region of rupture can be predicted by the region of the highest wall stress distribution. Embedded wall calcifications increase the local wall stress surrounding calcified spots, and eventually increases the risk of rupture. FSI results in streamlined AAA geometries show that the maximum stress on the aneurismal wall increases as the iliac bifurcation angle increases.
AB - Fluid structure interaction (FSI) simulations were conducted to assess the risk of rupture in reconstructed AAA from patients who had contained ruptured AAAs. The goal was to test to ability of our FSI methodology to predict the location of rupture, by correlating the high wall stress regions with the actual rupture location. We also present a parametric study in which the relationship of iliac bifurcation angle and the role of embedded calcifications were studied in respect to the aneurismal wall stress. The patient specific AAA FSI simulations were carried out with advanced constitutive material models of the various components of AAA, including models that describe the wall anisotropy, structural strength based on collagen fibers orientation within the arterial wall, AAA intraluminal thrombus (ILT), and embedded calcifications. The anisotropic material model used to describe the wall properties closely correlated with experimental results of AAA specimens [1]. The results demonstrate that the region of rupture can be predicted by the region of the highest wall stress distribution. Embedded wall calcifications increase the local wall stress surrounding calcified spots, and eventually increases the risk of rupture. FSI results in streamlined AAA geometries show that the maximum stress on the aneurismal wall increases as the iliac bifurcation angle increases.
UR - http://www.scopus.com/inward/record.url?scp=77953929104&partnerID=8YFLogxK
U2 - 10.1115/SBC2009-206490
DO - 10.1115/SBC2009-206490
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AN - SCOPUS:77953929104
SN - 9780791848913
T3 - Proceedings of the ASME Summer Bioengineering Conference 2009, SBC2009
SP - 5
EP - 6
BT - Proceedings of the ASME Summer Bioengineering Conference 2009, SBC2009
T2 - 11th ASME Summer Bioengineering Conference, SBC2009
Y2 - 17 June 2009 through 21 June 2009
ER -