A novel approach to normal responder patient with repeated implantation failures-a case report

Raoul Orvieto, Masha Brengauz, Baruch Feldman

Research output: Contribution to journalArticlepeer-review

Abstract

We describe a case of normal responder patients with repeated implantation failure who was offered the combination of the ultrashort GnRH-ag/ GnRH-ant COH protocol, followed by endometrial injury and a subsequent natural cycle frozen-thawed embryos transfer. The patient conceived following the natural FET cycle that was supported by luteal daily progesterone, with the additional single injection of HCG and GnRH-agonist, on day of ET and 4 days later, respectively. This combined approach seems to be a valuable tool in the armamentarium for treating normal responder patients with repeated implantation failures and should be further examined in large randomized controlled trials.

Original languageEnglish
Pages (from-to)435-437
Number of pages3
JournalGynecological Endocrinology
Volume31
Issue number6
DOIs
StatePublished - 1 Jun 2015

Keywords

  • Frozen-thawed embryo transfer
  • IVF outcome
  • Local injury
  • Mid-luteal GnRH-agonist
  • Repeated implantation failures
  • Ultrashort flare GnRH-agonist/GnRH antagonist

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