TY - JOUR
T1 - A novel approach to normal responder patient with repeated implantation failures-a case report
AU - Orvieto, Raoul
AU - Brengauz, Masha
AU - Feldman, Baruch
N1 - Publisher Copyright:
© 2015 Informa UK Ltd. All rights reserved.
PY - 2015/6/1
Y1 - 2015/6/1
N2 - We describe a case of normal responder patients with repeated implantation failure who was offered the combination of the ultrashort GnRH-ag/ GnRH-ant COH protocol, followed by endometrial injury and a subsequent natural cycle frozen-thawed embryos transfer. The patient conceived following the natural FET cycle that was supported by luteal daily progesterone, with the additional single injection of HCG and GnRH-agonist, on day of ET and 4 days later, respectively. This combined approach seems to be a valuable tool in the armamentarium for treating normal responder patients with repeated implantation failures and should be further examined in large randomized controlled trials.
AB - We describe a case of normal responder patients with repeated implantation failure who was offered the combination of the ultrashort GnRH-ag/ GnRH-ant COH protocol, followed by endometrial injury and a subsequent natural cycle frozen-thawed embryos transfer. The patient conceived following the natural FET cycle that was supported by luteal daily progesterone, with the additional single injection of HCG and GnRH-agonist, on day of ET and 4 days later, respectively. This combined approach seems to be a valuable tool in the armamentarium for treating normal responder patients with repeated implantation failures and should be further examined in large randomized controlled trials.
KW - Frozen-thawed embryo transfer
KW - IVF outcome
KW - Local injury
KW - Mid-luteal GnRH-agonist
KW - Repeated implantation failures
KW - Ultrashort flare GnRH-agonist/GnRH antagonist
UR - http://www.scopus.com/inward/record.url?scp=84938066836&partnerID=8YFLogxK
U2 - 10.3109/09513590.2015.1005595
DO - 10.3109/09513590.2015.1005595
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C2 - 25731193
AN - SCOPUS:84938066836
VL - 31
SP - 435
EP - 437
JO - Gynecological Endocrinology
JF - Gynecological Endocrinology
SN - 0951-3590
IS - 6
ER -