A new treatment algorithm for posttraumatic stress disorder

Jonathan Davidson*, Marcio Bernik, Kathryn M. Connor, Matthew J. Friedman, Kenneth O. Jobson, Yoshiharu Kim, Yves Lecrubier, Hong Ma, Frank Njenga, Dan J. Stein, Joseph Zohar

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review


Treating PTSD requires selecting an appropriate first-line treatment, deciding on length of treatment, and knowing when and how to change to another approach. The algorithm presented in this article provides sequential choices to decide whether to persist longer at the highest tolerated dose, augment with a second agent, or switch to another treatment. There is a need to evaluate levels of response (full, partial, or nonresponse), as well as to decide whether partial response is generalized to all PTSD symptoms or limited to select symptoms. Treatment strategies may then be based on which scenario is present. Issues of comorbidity and diagnostic reevaluation must be considered as well.

Original languageEnglish
Pages (from-to)887-898
Number of pages12
JournalPsychiatric Annals
Issue number11
StatePublished - Nov 2005


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