When we say that a scientific concept C changes, we mean that (1) at least some aspect or component of C varies, and (2) there is still something continuous in the historical development of C. However, how to account for the continuity in a radical conceptual change has been a difficulty. This chapter overcomes this difficulty by providing a new account of conceptual continuity in science. I begin with an examination of the historical development of the concept of dominance and highlight the inadequacies of the analytic, the cognitive, and the practice-based approaches. Then I introduce a holistic approach to conceptual change. By distinguishing two modes of continuity, I also propose a new mode of conceptual continuity. Finally, I illustrate and defend my approach by revisiting my historical case study.