A NAC gene regulating senescence improves grain protein, zinc, and iron content in wheat

Cristobal Uauy, Assaf Distelfeld, Tzion Fahima, Ann Blechl, Jorge Dubcovsky

Research output: Contribution to journalArticlepeer-review

Abstract

Enhancing the nutritional value of food crops is a means of improving human nutrition and health. We report here the positional cloning of Gpc-B1, a wheat quantitative trait locus associated with increased grain protein, zinc, and iron content. The ancestral wild wheat allele encodes a NAC transcription factor (NAM-B1) that accelerates senescence and increases nutrient remobilization from leaves to developing grains, whereas modern wheat varieties carry a nonfunctional NAM-B1 allele. Reduction in RNA levels of the multiple NAM homologs by RNA interference delayed senescence by more than 3 weeks and reduced wheat grain protein, zinc, and iron content by more than 30%.

Original languageEnglish
Pages (from-to)1298-1301
Number of pages4
JournalScience
Volume314
Issue number5803
DOIs
StatePublished - 24 Nov 2006
Externally publishedYes

Fingerprint

Dive into the research topics of 'A NAC gene regulating senescence improves grain protein, zinc, and iron content in wheat'. Together they form a unique fingerprint.

Cite this