A mouse model for eukaryotic translation initiation factor 2B-leucodystrophy reveals abnormal development of brain white matter

Keyphrases

• Brain Development 100%
• Mouse Model 100%
• Brain White Matter 100%
• IDH1-R132H 100%
• Abnormal Development 100%
• Eukaryotic Translation Initiation Factor 2B 100%
• Leukodystrophy 100%
• Brain Insult 66%
• Astrocytes 33%
• Magnetic Resonance Imaging 33%
• Clinically Significant 33%
• Genetic Background 33%
• Mutant Mice 33%
• Electron Microscopy 33%
• Catalytic Subunit 33%
• Tight 33%
• Stress Conditions 33%
• Translational Control 33%
• Housekeeping 33%
• Immunohistochemistry 33%
• Point mutation 33%
• Human Patients 33%
• Protein Synthesis 33%
• Young Animals 33%
• Oligodendrocyte 33%
• Unknown Etiology 33%
• Chronic Progressive 33%
• Gene Locus 33%
• White Matter 33%
• Translation Initiation Factor 33%
• Cuprizone-induced Demyelination 33%
• Myelin Formation 33%
• Nerve Fibers 33%
• Myelin Basic Protein 33%
• Brain Diseases 33%
• White Matter Disease 33%
• Myelin Maintenance 33%
• Small Caliber 33%
• Delayed Development 33%
• Leukoencephalopathy with Vanishing White Matter 33%

Neuroscience

• Translation Initiation 100%
• Guanine Nucleotide Exchange Factor 100%
• Leukodystrophy 100%
• Astrocyte 50%
• Magnetic Resonance Imaging 50%
• Enzyme Active Site 50%
• Point Mutation 50%
• Immunohistochemistry 50%
• Myelinogenesis 50%
• Encephalopathy 50%
• Protein Biosynthesis 50%
• Oligodendrocyte 50%
• Electron Microscopy 50%
• Gene Locus 50%
• Nerve Fiber 50%
• Myelin Protein 50%
• Leukoencephalopathy with Vanishing White Matter 50%