A modified surgical technique for submacular injection

Avi Ohayon, Shulamit Schwartz, Anat Loewenstein, Daniel Seknazi, Eric H. Souied, Adiel Barak

Research output: Contribution to journalArticlepeer-review


BACKGROUND AND OBJECTIVE: To describe a modified simple surgical technique for submacular injection. PATIENTS AND METHODS: The technique involves pars plana vitrectomy, a viscous fluid control (VFC) system for semi-automatic subretinal injection of tissue plasminogen activator (tPA), bevacizumab, and air and intravitreal gas injection for submacular hemorrhage (SMH), or subretinal balanced salt solution (BSS) for submacular perfluorocarbon (PFC) bubbles or persistent macular holes. RESULTS: This technique was successfully performed for SMH (five patients), a subfoveal PFC bubble (two patients), and persistent full-thickness macular hole (FTMH) (one patient). The single surgical complication was an FTMH in a PFC bubble. Four SMH patients had postoperative displacement of the hemorrhage. The FTMH was partially closed. CONCLUSIONS: Semi-automatic subretinal injection of tPA, bevacizumab, and air with the VFC system promoted displacement and clearance of SMH without complications. A subretinal BSS injection is effective for removing subfoveal PFC bubbles and for closing persistent FTMH.

Original languageEnglish
Pages (from-to)551-555
Number of pages5
JournalOphthalmic Surgery Lasers and Imaging Retina
Issue number10
StatePublished - Oct 2021


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