TY - GEN
T1 - A Magnetically and Electrically Powered Hybrid Micromotor in Conductive Solutions
AU - Wu, Yue
AU - Yakov, Sivan
AU - Yossifon, Gilad
N1 - Publisher Copyright:
© 2021 MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. All rights reserved.
PY - 2021
Y1 - 2021
N2 - Electrically powered micro- and nanomotors are promising tools for in-vitro single-cell analysis. However, electrical propulsion of these micromotors becomes ineffective at solution conductivities exceeding ~0.3mS/cm. Here, we successfully extended janus particle (JP) cargo manipulation and transport capabilities to conductive near-physiological (<6mS/cm) solutions by combining magnetic field-based micromotor propulsion and navigation with DEP-based manipulation of various cargos (synthetic particles, bacteria, red blood cells, and mammalian cells). This hybrid micromotor approach for label-free trapping and transport of selected live cells within conductive solutions, opens new opportunities in drug delivery and single cell analysis, where close-to-physiological media conditions are necessary.
AB - Electrically powered micro- and nanomotors are promising tools for in-vitro single-cell analysis. However, electrical propulsion of these micromotors becomes ineffective at solution conductivities exceeding ~0.3mS/cm. Here, we successfully extended janus particle (JP) cargo manipulation and transport capabilities to conductive near-physiological (<6mS/cm) solutions by combining magnetic field-based micromotor propulsion and navigation with DEP-based manipulation of various cargos (synthetic particles, bacteria, red blood cells, and mammalian cells). This hybrid micromotor approach for label-free trapping and transport of selected live cells within conductive solutions, opens new opportunities in drug delivery and single cell analysis, where close-to-physiological media conditions are necessary.
KW - Dielectrophoresis
KW - in-vitro single-cell analysis
KW - micro- and nanomotor
UR - http://www.scopus.com/inward/record.url?scp=85136919377&partnerID=8YFLogxK
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AN - SCOPUS:85136919377
T3 - MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences
SP - 595
EP - 596
BT - MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PB - Chemical and Biological Microsystems Society
T2 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021
Y2 - 10 October 2021 through 14 October 2021
ER -