A hypothesis on the possible role of interferon in the initiation of acute gouty arthritis attack

A. Weinberger; J. Pinkhas

doi:10.1016/0306-9877(80)90002-X

A hypothesis on the possible role of interferon in the initiation of acute gouty arthritis attack

A. Weinberger^*, J. Pinkhas

^*Corresponding author for this work

Rabin Medical Center Israel

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

There is some evidence that unidentified factors might play a role in the initial events of acute gouty arthritis. Serum interferon activity was found to be high in several arthritides; interferon stimulates the production of prostaglandin E, an established mediator of inflammation. It is postulated that interferon can play a role in the pathogenesis of an acute gouty arthritis.

Original language	English
Pages (from-to)	781-784
Number of pages	4
Journal	Medical Hypotheses
Volume	6
Issue number	8
DOIs	https://doi.org/10.1016/0306-9877(80)90002-X
State	Published - 1980
Externally published	Yes

Keywords

Arthritis
Gout
Interferon
Urate crystals

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10.1016/0306-9877(80)90002-X

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abstract = "There is some evidence that unidentified factors might play a role in the initial events of acute gouty arthritis. Serum interferon activity was found to be high in several arthritides; interferon stimulates the production of prostaglandin E, an established mediator of inflammation. It is postulated that interferon can play a role in the pathogenesis of an acute gouty arthritis.",

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AB - There is some evidence that unidentified factors might play a role in the initial events of acute gouty arthritis. Serum interferon activity was found to be high in several arthritides; interferon stimulates the production of prostaglandin E, an established mediator of inflammation. It is postulated that interferon can play a role in the pathogenesis of an acute gouty arthritis.

KW - Arthritis

KW - Gout

KW - Interferon

KW - Urate crystals

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A hypothesis on the possible role of interferon in the initiation of acute gouty arthritis attack

Abstract

Keywords

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