@article{dd423dadc41942b2b012a5570abeee54,
title = "A human gene (DDX10) encoding a putative DEAD-box RNA helicase at 11q22-q23",
abstract = "A human gene encoding a putative RNA helicase, designated DDX10, was identified 400 kb telomeric to the ataxia-telangiectasia gene at chromosome 11q22-q23. The predicted amino acid sequence shows very high similarity to a subgroup of DEAD-box RNA helicases involved in ribosome biogenesis. This novel gene encodes a 3.2-kb transcript in a variety of human tissues. A processed pseudogene of DDX10 was detected at chromosome 9q21-q22. We observed a rare trinucleotide repeat length polymorphism within the coding sequence of DDX10.",
author = "Kinneret Savitsky and Yael Ziv and Anat Bar-Shira and Shlomit Gilad and Tagle, {Danilo A.} and Sara Smith and Tamar Uziel and Sharon Sfez and Joseph Nahmias and Adam Sartiel and Eddy, {Roger L.} and Shows, {Thomas B.} and Collins, {Francis S.} and Yosef Shiloh and Galit Rotman",
note = "Funding Information: Screening of the chromosome 9-speci{\textregistered}c cosmid library. The chromosome 9-speci{\textregistered}c cosmid library LL09NC01``P'' was constructed at the Biomedical Sciences Division, Lawrence Livermore National Laboratory (Livermore, CA), under the auspices of the National Laboratory Gene Library Project sponsored by the U.S. Department of Energy. Screening of the cosmid library and analysis of the clones by HinfI {\textregistered}ngerprinting was performed as described in Nahmias et al. (1995). FISH analysis was performed as in Gharib et al. (1993). Funding Information: We are indebted to Drs. Carol Jones and Frances Benham for gifts of somatic cell hybrids and to Dr. Toru Miki for the {\textregistered}broblast cDNA library. We thank N. Hornigold for the analysis of the HinfI {\textregistered}nger-printing data and R. Ekong for the in situ hybridization. This work was supported by research grants from the A-T Children's Project, the A-T Medical Research Foundation, the Thomas Appeal (A-T Medical Research Trust), The United States±Israel Binational Science Foundation, and the National Institute of Neurological Disorders and Stroke (NS31763). This work was carried out in partial ful{\textregistered}llment of the requirements for the Ph.D. degree to K.S.",
year = "1996",
month = apr,
day = "15",
doi = "10.1006/geno.1996.0184",
language = "אנגלית",
volume = "33",
pages = "199--206",
journal = "Genomics",
issn = "0888-7543",
publisher = "Academic Press Inc.",
number = "2",
}