A comparison of perioperative morbidity, perioperative mortality, and disease-specific survival in elderly women (≥70 years) versus younger women (<70 years) with endometrioid endometrial cancer

Zvi Vaknin, Ido Ben-Ami, David Schneider, Moty Pansky, Reuvit Halperin

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: The study compares the perioperative morbidity and mortality rates of elderly (≥70 years) and younger (<70 years) patients with endometrioid endometrial cancer. Methods: The study cohort consisted of 115 consecutive women undergoing explorative laparotomy because of endometrioid endometrial cancer. Clinical data included patients' age, comorbidities, chronic use of medications, body mass index (kg/m2), previous surgical procedures, surgical International Federation of Gynecology and Obstetrics stage, histological grade, relevant prognostic factors, a number of dissected lymph nodes, occurrence of perioperative complications, postoperative hospital stay (in days), and long-term diseasespecific survival (in months). Results: Patients were divided into 2 groups: those younger than 70 years (group 1: 84 women, 73%) and those 70 years or older (group 2: 31 women, 27%). Although, as expected, elderly women had more major comorbidities, the rate of perioperative complications was similar between the 2 groups. In a logistic regression model, only chronic lung disease, gastrointestinal disease, and past abdominal surgery correlated with a higher rate of perioperative complications. None of the cohort patients died during the perioperative period. The long-term disease-specific survival was significantly poorer for the older group. Conclusion: Chronological age by itself should not be a contraindication for the proper surgical treatment of elderly women with endometrioid endometrial cancer, because it is a poor predicting factor for perioperative morbidity and mortality.

Original languageEnglish
Pages (from-to)879-883
Number of pages5
JournalInternational Journal of Gynecological Cancer
Volume19
Issue number5
DOIs
StatePublished - Jul 2009
Externally publishedYes

Keywords

  • Elderly women
  • Endometrioid endometrial cancer
  • Gyneco-oncological surgery
  • Perioperative outcome

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