A case of salicylate intoxication complicated by coagulopathy, pulmonary edema, and pancreatitis

Itay Ayalon; Matthew Noble Alder; Travis Ryan Langner; Einar Thor Hafberg; Alexander Gerhard Miethke; Jennifer Melissa Kaplan

doi:10.1097/MJT.0000000000000385

A case of salicylate intoxication complicated by coagulopathy, pulmonary edema, and pancreatitis

Itay Ayalon^*, Matthew Noble Alder, Travis Ryan Langner, Einar Thor Hafberg, Alexander Gerhard Miethke, Jennifer Melissa Kaplan

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

The large availability of salicylic acid products makes them an often encountered source of poisoning in the emergency department. Even though in most cases the prognosis is good, with a low incidence of long-term morbidity and mortality, complications do occur, and some of those can be life threatening. We present an unusual case of salicylate intoxication in an adolescent in which several uncommon complications (severe coagulopathy, pulmonary edema, and pancreatitis) conjoined together. We review the literature and discuss the complications pathogenesis and differential diagnosis. We suggest that these potentially life-threatening complications be acknowledged, investigated, and rapidly treated.

Original language	English
Pages (from-to)	e1929-e1932
Journal	American Journal of Therapeutics
Volume	23
Issue number	6
DOIs	https://doi.org/10.1097/MJT.0000000000000385
State	Published - 28 Nov 2016
Externally published	Yes

Keywords

Aspirin
Coagulopathy
Intoxication
Pancreatitis
Pulmonary edema
Salicylate
Salicylic acid
Salicylism

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10.1097/MJT.0000000000000385

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title = "A case of salicylate intoxication complicated by coagulopathy, pulmonary edema, and pancreatitis",

abstract = "The large availability of salicylic acid products makes them an often encountered source of poisoning in the emergency department. Even though in most cases the prognosis is good, with a low incidence of long-term morbidity and mortality, complications do occur, and some of those can be life threatening. We present an unusual case of salicylate intoxication in an adolescent in which several uncommon complications (severe coagulopathy, pulmonary edema, and pancreatitis) conjoined together. We review the literature and discuss the complications pathogenesis and differential diagnosis. We suggest that these potentially life-threatening complications be acknowledged, investigated, and rapidly treated.",

keywords = "Aspirin, Coagulopathy, Intoxication, Pancreatitis, Pulmonary edema, Salicylate, Salicylic acid, Salicylism",

author = "Itay Ayalon and Alder, {Matthew Noble} and Langner, {Travis Ryan} and Hafberg, {Einar Thor} and Miethke, {Alexander Gerhard} and Kaplan, {Jennifer Melissa}",

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AU - Alder, Matthew Noble

AU - Langner, Travis Ryan

AU - Hafberg, Einar Thor

AU - Miethke, Alexander Gerhard

AU - Kaplan, Jennifer Melissa

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AB - The large availability of salicylic acid products makes them an often encountered source of poisoning in the emergency department. Even though in most cases the prognosis is good, with a low incidence of long-term morbidity and mortality, complications do occur, and some of those can be life threatening. We present an unusual case of salicylate intoxication in an adolescent in which several uncommon complications (severe coagulopathy, pulmonary edema, and pancreatitis) conjoined together. We review the literature and discuss the complications pathogenesis and differential diagnosis. We suggest that these potentially life-threatening complications be acknowledged, investigated, and rapidly treated.

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KW - Intoxication

KW - Pancreatitis

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A case of salicylate intoxication complicated by coagulopathy, pulmonary edema, and pancreatitis

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