A Biphasic COVID-19 Clinical Course in Anti-CD20 Treated Patients: Case Series and Review of the Literature

Noa Bigman-Peer; Eyal Peer; Barak Pertzov; Mordechai Kramer; Gad Segal; Noa Eliakim-Raz

doi:10.12890/2022_003502

A Biphasic COVID-19 Clinical Course in Anti-CD20 Treated Patients: Case Series and Review of the Literature

Noa Bigman-Peer, Eyal Peer, Barak Pertzov, Mordechai Kramer, Gad Segal, Noa Eliakim-Raz

Internal Medicine

Research output: Contribution to journal › Review article › peer-review

2 Scopus citations

Abstract

We describe four cases of COVID-19 infection during the Omicron wave, in patients treated with anti-CD20 monoclonal antibodies. All cases follow a similar biphasic clinical course consisting of respiratory deterioration, which occurred a few weeks after convalescence from initial mild to asymptomatic infection. Possible explanations are discussed.

Original language	English
Journal	European Journal of Case Reports in Internal Medicine
Volume	9
Issue number	8
DOIs	https://doi.org/10.12890/2022_003502
State	Published - 2022

Keywords

COVID-19
Omicron
anti-CD20
obinutuzumab
rituximab

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10.12890/2022_003502

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abstract = "We describe four cases of COVID-19 infection during the Omicron wave, in patients treated with anti-CD20 monoclonal antibodies. All cases follow a similar biphasic clinical course consisting of respiratory deterioration, which occurred a few weeks after convalescence from initial mild to asymptomatic infection. Possible explanations are discussed.",

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AU - Eliakim-Raz, Noa

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A Biphasic COVID-19 Clinical Course in Anti-CD20 Treated Patients: Case Series and Review of the Literature

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Keywords

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