A Biphasic COVID-19 Clinical Course in Anti-CD20 Treated Patients: Case Series and Review of the Literature

Noa Bigman-Peer, Eyal Peer, Barak Pertzov, Mordechai Kramer, Gad Segal, Noa Eliakim-Raz

Research output: Contribution to journalReview articlepeer-review

Abstract

We describe four cases of COVID-19 infection during the Omicron wave, in patients treated with anti-CD20 monoclonal antibodies. All cases follow a similar biphasic clinical course consisting of respiratory deterioration, which occurred a few weeks after convalescence from initial mild to asymptomatic infection. Possible explanations are discussed.

Original languageEnglish
JournalEuropean Journal of Case Reports in Internal Medicine
Volume9
Issue number8
DOIs
StatePublished - 2022

Keywords

  • anti-CD20
  • COVID-19
  • obinutuzumab
  • Omicron
  • rituximab

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