A biologically-based algorithm for companding computerized tomography (CT) images

Hadar Cohen-Duwek*, Hedva Spitzer, Rony Weitzen, Sara Apter

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Computerized Tomography (CT) images are High Dynamic Range (HDR) images of the X-ray attenuation coefficients of the body's tissues. The inability to see abnormalities in tissues with marked differences in their X-ray attenuation coefficients, in a single CT window, poses a significant clinical problem in radiology. In order to provide proper contrast, which reveals all the required clinical details within each specifically imaged tissue, a single CT slice must be viewed by a radiologist four times: the first viewing focuses on the lung window; the second viewing focuses on the soft tissues window; the third viewing focuses on the liver window; and the fourth viewing focuses on the bone window. In order to enhance the ability to perform a complete diagnosis, while decreasing diagnostic time, we developed the BACCT (Biologically-based Algorithm for Companding CT images) method. Our algorithm compresses and expands (compands) the HDR CT image into a single, low dynamic range image. Before performing the companding procedure, unique processing is required which involves operations that enhance and stretch the image. The performance of our algorithm has been demonstrated on a large repertoire of CT body images. All the clinically required CT information is exposed in each CT slice in a single image. The algorithm compands the CT images in a fully automatic way. Collaborating radiologists have already tested the results of our algorithmic method, and reported that the images seem to provide all the necessary information. However, clinical tests for statistical reliability are still required.

Original languageEnglish
Pages (from-to)367-379
Number of pages13
JournalComputers in Biology and Medicine
Issue number6
StatePublished - Jun 2011


FundersFunder number
Israeli Ministry of Science
AAMN Foundation


    • CT
    • High dynamic range compression


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