A 25-year control of idiopathic ventricular fibrillation with electrophysiologic-guided antiarrhythmic drug therapy

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Abstract

The case of a 28-year-old man with recurrent syncope and multiple documented episodes of idiopathic ventricular fibrillation is reported. Recurrent syncope suggesting a self-terminating ventricular tachyarrhythmia occurred after 1 month of amiodarone therapy, and ventricular fibrillation was inducible at electrophysiologic study. After addition of quinidine, no significant ventricular arrhythmias could be induced. Similar results were found during a repeat electrophysiologic study performed 23.5 years later. During a 25-year period, the patient has remained arrhythmia-free on combined antiarrhythmic medication with quinidine and amiodarone.

Original languageEnglish
Pages (from-to)352-354
Number of pages3
JournalHeart Rhythm
Volume1
Issue number3
DOIs
StatePublished - Sep 2004

Keywords

  • Amiodarone
  • Electrophysiologic study
  • Quinidine
  • Ventricular fibrillation

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