A 2012 evidence-based algorithm for the pharmacotherapy for obsessive-compulsive disorder

Dan J. Stein*, Nastassja Koen, Naomi Fineberg, Leonardo F. Fontenelle, Hisato Matsunaga, David Osser, H. Blair Simpson

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

57 Scopus citations

Abstract

There is a need to synthesize the growing body of literature on the pharmacotherapeutic management of patients with obsessive-compulsive disorder for clinicians working at a primary care level. We have aimed to generate a simple, easy-to-follow algorithm for the primary care practitioner. This seven-step algorithm addresses diagnosis of obsessive-compulsive disorder, initiation of pharmacotherapy, monitoring and maintenance treatment, and guidelines for the management of patients who are resistant to initial therapy. In creating this algorithm, we have drawn on the body of published evidence, as well as on expert opinion.

Original languageEnglish
Pages (from-to)211-219
Number of pages9
JournalCurrent Psychiatry Reports
Volume14
Issue number3
DOIs
StatePublished - Jun 2012
Externally publishedYes

Funding

FundersFunder number
International College Of OC Spectrum Disorders
Janssen Pharmaceutica
Neuropharm Ltd
Rio de Janeiro State Research Support Foundation
Transcept Pharmaceuticals
National Institute of Mental Health
Abbott Laboratories
Bristol-Myers Squibb
AstraZeneca
Wellcome
Solvay Pharmaceuticals
Japan Society for the Promotion of Science22591294
Conselho Nacional de Desenvolvimento Científico e Tecnológico
Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro
Servier

    Keywords

    • Algorithm
    • Anxiety disorders
    • Evidence-based
    • Obsessive-compulsive disorder
    • OCD
    • Pharmacotherapy
    • Primary care
    • Treatment

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