1540-nm fractional erbium: Glass laser is a safe and effective modality for nonablative facial rejuvenation

Efrat Solomon-Cohen*, Moshe Lapidoth, Daniel Mimouni, Lehavit Akerman, Dan Slodownik, Emmilia Hodak, Assi Levi

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Background: Laser treatments for facial rejuvenation are common, with ablative modalities being of more common use for this indication. Efficient nonablative modalities are of rising demand. Aim: Our aim was to determine the safety and efficacy of high-fluence, nonablative 1540-nm fractional Erbium:glass laser for facial rejuvenation. Patients and Methods: A retrospective study of patients treated with 3-4 treatments using the 1540-nm fractional Erbium:glass laser for facial rejuvenation, using 2500-3000 mJ/stacked pulses (51-61 mJ per pixel). Patients were followed-up for 3 months following their last treatment. Before and after photos were independently blindly evaluated by 2 dermatologists, who graded them using a scale from 0 (exacerbation) to 4 (76%-100% improvement) for 2 different facial regions (frontal face region and lateral canthal region). Pain perception and adverse effects as well as patient satisfaction were documented throughout the study. Results: Sixteen patients completed both treatment and follow-up period. At the 3-months posttreatment follow-up visit, moderate-to-significant improvement in rhytids appearance (mean grade of improvement: 2.93 for frontal face and 3 for lateral canthal region) was observed. Patients’ satisfaction was high (4.25). Patients reported mild and transient erythema posttreatment with no other adverse effects. Conclusion: The high-fluence 1540-nm fractional Erbium:glass laser is a safe and effective nonablative modality for facial rejuvenation.

Original languageEnglish
Pages (from-to)1679-1683
Number of pages5
JournalJournal of Cosmetic Dermatology
Issue number6
StatePublished - Jun 2021


  • Erbium:glass laser
  • facial rejuvenation
  • nonablative laser
  • rhytids
  • wrinkles


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