TY - JOUR
T1 - β-blockers in hypertension
T2 - Is carvedilol different?
AU - Messerli, Franz H.
AU - Grossman, Ehud
PY - 2004/5/6
Y1 - 2004/5/6
N2 - Most studies assessing the effects of β-blockers were carried out with traditional, β1-selective β-blockers, such as metoprolol and atenolol. Pathophysiologic and pharmacologic studies have documented that not all β-blockers are created equal. In particular, the pharmacologic and clinical profiles of the newer, vasodilating β-blockers, such as carvedilol, have been shown to differ from those of the traditional β-blockers. These differences, although relevant in the younger patient with hypertension, are particularly important in elderly patients in whom traditional β-blockers may not be as effective or as well tolerated as the newer vasodilating agents.
AB - Most studies assessing the effects of β-blockers were carried out with traditional, β1-selective β-blockers, such as metoprolol and atenolol. Pathophysiologic and pharmacologic studies have documented that not all β-blockers are created equal. In particular, the pharmacologic and clinical profiles of the newer, vasodilating β-blockers, such as carvedilol, have been shown to differ from those of the traditional β-blockers. These differences, although relevant in the younger patient with hypertension, are particularly important in elderly patients in whom traditional β-blockers may not be as effective or as well tolerated as the newer vasodilating agents.
UR - http://www.scopus.com/inward/record.url?scp=2442490999&partnerID=8YFLogxK
U2 - 10.1016/j.amjcard.2004.01.020
DO - 10.1016/j.amjcard.2004.01.020
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AN - SCOPUS:2442490999
VL - 93
SP - 7
EP - 12
JO - American Journal of Cardiology
JF - American Journal of Cardiology
SN - 0002-9149
IS - 9 SUPPL. 1
ER -