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Dive into the research topics where Yossi Roitelman is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Research output
- 31 Article
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Haploid mammalian genetic screen identifes UBXD8 as a key determinant of HMGCR degradation and cholesterol biosynthesis
Loregger, A., Raaben, M., Tan, J., Scheij, S., Moeton, M., Van Den Berg, M., Gelberg-Etel, H., Stickel, E., Roitelman, J., Brummelkamp, T. & Zelcer, N., 2017, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 37, 11, p. 2064-2074 11 p.Research output: Contribution to journal › Article › peer-review
Open Access30 Scopus citations -
Differential regulation of HMG-CoA reductase and Insig-1 by enzymes of the ubiquitin-proteasome system
Tsai, Y. C., Leichner, G. S., Pearce, M. M. P., Wilson, G. L., Wojcikiewicz, R. J. H., Roitelman, J. & Weissman, A. M., 2012, In: Molecular Biology of the Cell. 23, 23, p. 4484-4494 11 p.Research output: Contribution to journal › Article › peer-review
65 Scopus citations -
Metabolically regulated endoplasmic reticulum-associated degradation of 3-hydroxy-3-methylglutaryl-CoA reductase: Evidence for requirement of a geranylgeranylated protein
Leichner, G. S., Avner, R., Harats, D. & Roitelman, J., 16 Sep 2011, In: Journal of Biological Chemistry. 286, 37, p. 32150-32161 12 p.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
Dislocation of HMG-CoA reductase and Insig-1, two polytopic endoplasmic reticulum proteins, en route to proteasomal degradation
Leichner, G. S., Avner, R., Harats, D. & Roitelman, J., 15 Jul 2009, In: Molecular Biology of the Cell. 20, 14, p. 3330-3341 12 p.Research output: Contribution to journal › Article › peer-review
Open Access41 Scopus citations -
SPFH1 and SPFH2 mediate the ubiquitination and degradation of inositol 1,4,5-trisphosphate receptors in muscarinic receptor-expressing HeLa cells
Wang, Y., Pearce, M. M. P., Sliter, D. A., Olzmann, J. A., Christianson, J. C., Kopito, R. R., Boeckmann, S., Gagen, C., Leichner, G. S., Roitelman, J. & Wojcikiewicz, R. J. H., Nov 2009, In: Biochimica et Biophysica Acta - Molecular Cell Research. 1793, 11, p. 1710-1718 9 p.Research output: Contribution to journal › Article › peer-review
Open Access26 Scopus citations