Yoram Cohen

2024

Addressing the Opioids Lipophilicity Challenge via a Straightforward and Simultaneous ¹H NMR-Based logP/D Determination, Both Separately and in Mixtures

Yeffet, D., Columbus, I., Parvari, G., Eichen, Y., Saphier, S., Ghindes-Azaria, L., Redy-Keisar, O., Amir, D., Drug, E., Gershonov, E., Binyamin, I., Cohen, Y., Karton-Lifshin, N. & Zafrani, Y., 25 Jul 2024, In: Journal of Medicinal Chemistry. 67, 14, p. 12399-12409 11 p.

Research output: Contribution to journal › Article › peer-review

Advanced ¹⁹F-NMR studies shed new light on encapsulation of isosteric guests in the hexameric capsules of resorcin[4]arenes and pyrogallol[4]arenes

Slovak, S., Salem, T., Horin, I., Avram, L. & Cohen, Y., 28 Feb 2024, In: Organic Chemistry Frontiers. 11, 12, p. 3294-3301 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

2023

Harnessing Pillar[5]arene Host–Guest Complexation To Improve pH Stability and Affect Enzymatic Degradation of the Anticancer Prodrug Capecitabine: A ¹⁹F NMR Study

Horin, I., Slovak, S. & Cohen, Y., 6 Sep 2023, In: Chemistry - A European Journal. 29, 50, e202301628.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Species-specific lipophilicities of fluorinated diketones in complex equilibria systems and their potential as multifaceted reversible covalent warheads

Columbus, I., Ghindes-Azaria, L., Herzog, I. M., Blum, E., Parvari, G., Eichen, Y., Cohen, Y., Gershonov, E., Drug, E., Saphier, S., Elias, S., Smolkin, B. & Zafrani, Y., Dec 2023, In: Communications Chemistry. 6, 1, 197.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

2022

Diffusion NMR Reveals the Structures of the Molecular Aggregates of Resorcin[4]arenes and Pyrogallol[4]arenes in Aromatic and Chlorinated Solvents

Horin, I., Slovak, S. & Cohen, Y., 24 Nov 2022, In: Journal of Physical Chemistry Letters. 13, 46, p. 10666-10670 5 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Supramolecular catalysis in confined space: making the pyrogallol[4]arene capsule catalytically active in non-competitive solvent

La Manna, P., Talotta, C., Gaeta, C., Cohen, Y., Slovak, S., Rescifina, A., Sala, P. D., De Rosa, M., Soriente, A. & Neri, P., 15 Mar 2022, In: Organic Chemistry Frontiers. 9, 9, p. 2453-2463 11 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

2021

Aggregation Mode, Host-Guest Chemistry in Water, and Extraction Capability of an Uncharged, Water-Soluble, Liquid Pillar[5]arene Derivative

Horin, I., Shalev, O. & Cohen, Y., Nov 2021, In: ChemistryOpen. 10, 11, p. 1111-1115 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Design Guidelines for Cationic Pillar[n]arenes that Prevent Biofilm Formation by Gram-Positive Pathogens

Kaizerman-Kane, D., Hadar, M., Joseph, R., Logviniuk, D., Zafrani, Y., Fridman, M. & Cohen, Y., 12 Mar 2021, In: ACS Infectious Diseases. 7, 3, p. 579-585 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

22 Scopus citations

Solution NMR of synthetic cavity containing supramolecular systems: what have we learned on and from?

Cohen, Y., Slovak, S. & Avram, L., 14 Sep 2021, In: Chemical Communications. 57, 71, p. 8856-8884 29 p.

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

2020

Constant gradient FEXSY: A time-efficient method for measuring exchange

Scher, Y., Reuveni, S. & Cohen, Y., Feb 2020, In: Journal of Magnetic Resonance. 311, 106667.

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Kinetic Stabilities and Exchange Dynamics of Water-Soluble Bis-Formamide Caviplexes Studied Using Diffusion-Ordered NMR Spectroscopy (DOSY)

Escobar, L., Li, Y. S., Cohen, Y., Yu, Y., Rebek, J. & Ballester, P., 2 Jul 2020, In: Chemistry - A European Journal. 26, 37, p. 8220-8225 6 p.

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Temperature-Dependent and pH-Responsive Pillar[5]arene-Based Complexes and Hydrogen-Bond-Based Supramolecular Pentagonal Boxes in Water

Hadar, M., Kaizerman-Kane, D., Zafrani, Y. & Cohen, Y., 1 Sep 2020, In: Chemistry - A European Journal. 26, 49, p. 11250-11255 6 p.

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

2019

Diffusion NMR for the characterization, in solution, of supramolecular systems based on calixarenes, resorcinarenes, and other macrocyclic arenes

Cohen, Y. & Slovak, S., 21 May 2019, In: Organic Chemistry Frontiers. 6, 10, p. 1705-1718 14 p.

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

High Exchange Rate Complexes of ¹²⁹ Xe with Water-Soluble Pillar[5]arenes for Adjustable Magnetization Transfer MRI

Schnurr, M., Joseph, R., Naugolny-Keisar, A., Kaizerman-Kane, D., Bogdanoff, N., Schuenke, P., Cohen, Y. & Schröder, L., 21 Jan 2019, In: ChemPhysChem. 20, 2, p. 246-251 6 p.

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

pH-Responsive Pillar[6]arene-based Water-Soluble Supramolecular Hexagonal Boxes

Kaizerman-Kane, D., Hadar, M., Tal, N., Dobrovetsky, R., Zafrani, Y. & Cohen, Y., 8 Apr 2019, In: Angewandte Chemie - International Edition. 58, 16, p. 5302-5306 5 p.

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

Relative hydrophilicities of cis and trans formamides

Li, Y. S., Escobar, L., Zhu, Y. J., Cohen, Y., Ballester, P., Rebek, J. & Yu, Y., 1 Oct 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 40, p. 19815-19820 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

Role of CB₂ Receptor in the Recovery of Mice after Traumatic Brain Injury

Magid, L., Heymann, S., Elgali, M., Avram, L., Cohen, Y., Liraz-Zaltsman, S., Mechoulam, R. & Shohami, E., Jun 2019, In: Journal of Neurotrauma. 36, 11, p. 1836-1846 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

24 Scopus citations

Shape induced sorting: Via rim-to-rim complementarity in the formation of pillar[5, 6]arene-based supramolecular organogels

Kaizerman-Kane, D., Hadar, M., Granot, E., Patolsky, F., Zafrani, Y. & Cohen, Y., 7 Oct 2019, In: Organic Chemistry Frontiers. 6, 19, p. 3348-3354 7 p.

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Single- and double-Diffusion encoding MRI for studying ex vivo apparent axon diameter distribution in spinal cord white matter

Anaby, D., Morozov, D., Seroussi, I., Hametner, S., Sochen, N. & Cohen, Y., 1 Dec 2019, In: NMR in Biomedicine. 32, 12, e4170.

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

2018

Bis-resorcin[4]arene Selectively Forms Hexameric Capsules in Apolar Solvents: Evidence from Diffusion NMR

Horin, I., Adiri, T., Zafrani, Y. & Cohen, Y., 6 Jul 2018, In: Organic Letters. 20, 13, p. 3958-3961 4 p.

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Pillararene-Based Two-Component Thixotropic Supramolecular Organogels: Complementarity and Multivalency as Prominent Motifs

Zafrani, Y., Kaizerman, D., Hadar, M., Bigan, N., Granot, E., Ghosh, M., Adler-Abramovich, L., Patolsky, F. & Cohen, Y., 22 Oct 2018, In: Chemistry - A European Journal. 24, 59, p. 15750-15755 6 p.

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Special Issue: Pillararenes – The First Decade

Cohen, Y. & Ogoshi, T., Nov 2018, In: Israel Journal of Chemistry. 58, 11, p. 1151 1 p.

Research output: Contribution to journal › Editorial

Open Access

2 Scopus citations

2017

Calix[4, 5]tetrolarenes: A New Family of Macrocycles

Zafrani, Y. & Cohen, Y., 21 Jul 2017, In: Organic Letters. 19, 14, p. 3719-3722 4 p.

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Diffusion MRI of the spinal cord: from structural studies to pathology

Cohen, Y., Anaby, D. & Morozov, D., 1 Mar 2017, In: NMR in Biomedicine. 30, 3, e3592.

Research output: Contribution to journal › Review article › peer-review

31 Scopus citations

Studying microstructure and microstructural changes in plant tissues by advanced diffusion magnetic resonance imaging techniques

Morozov, D., Tal, I., Pisanty, O., Shani, E. & Cohen, Y., 1 Apr 2017, In: Journal of Experimental Botany. 68, 9, p. 2245-2257 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

2016

Cationic Pillararenes Potently Inhibit Biofilm Formation without Affecting Bacterial Growth and Viability

Joseph, R., Naugolny, A., Feldman, M., Herzog, I. M., Fridman, M. & Cohen, Y., 27 Jan 2016, In: Journal of the American Chemical Society. 138, 3, p. 754-757 4 p.

Research output: Contribution to journal › Article › peer-review

181 Scopus citations

Conventions and nomenclature for double diffusion encoding NMR and MRI

Shemesh, N., Jespersen, S. N., Alexander, D. C., Cohen, Y., Drobnjak, I., Dyrby, T. B., Finsterbusch, J., Koch, M. A., Kuder, T., Laun, F., Lawrenz, M., Lundell, H., Mitra, P. P., Nilsson, M., Özarslan, E., Topgaard, D. & Westin, C. F., 1 Jan 2016, In: Magnetic Resonance in Medicine. 75, 1, p. 82-87 6 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

148 Scopus citations

Encapsulated or Not Encapsulated? Ammonium Salts Can Be Encapsulated in Hexameric Capsules of Pyrogallol[4]arene

Yariv-Shoushan, S. & Cohen, Y., 4 Mar 2016, In: Organic Letters. 18, 5, p. 936-939 4 p.

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Fluorinated smart micelles as enzyme-responsive probes for ¹⁹F-magnetic resonance

Buzhor, M., Avram, L., Frish, L., Cohen, Y. & Amir, R. J., 2016, In: Journal of Materials Chemistry B. 4, 18, p. 3037-3042 6 p.

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Hexameric capsules studied by magic angle spinning solid-state NMR spectroscopy: Identifying solvent molecules in pyrogallol[4]arene capsules

Avram, L., Goldbourt, A. & Cohen, Y., 18 Jan 2016, In: Angewandte Chemie - International Edition. 55, 3, p. 904-907 4 p.

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Hydrogen bond hexameric capsules: Structures, host-guest interactions, guest affinities, and catalysis

Cohen, Y., Slovak, S. & Avram, L., 1 Jan 2016, Calixarenes and Beyond. Springer, p. 811-842 32 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

4 Scopus citations

Phosphonium pillar[5]arenes as a new class of efficient biofilm inhibitors: Importance of charge cooperativity and the pillar platform

Joseph, R., Kaizerman, D., Herzog, I. M., Hadar, M., Feldman, M., Fridman, M. & Cohen, Y., 2016, In: Chemical Communications. 52, 70, p. 10656-10659 4 p.

Research output: Contribution to journal › Article › peer-review

48 Scopus citations

Pore sizes and directionality in microcapillaries from angular double-pulsed-field-gradient NMR

Morozov, D., Bar, L., Sochen, N. & Cohen, Y., 1 May 2016, In: Microporous and Mesoporous Materials. 225, p. 105-115 11 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

2015

Diffusion NMR of molecular cages and capsules

Avram, L. & Cohen, Y., 21 Jan 2015, In: Chemical Society Reviews. 44, 2, p. 586-602 17 p.

Research output: Contribution to journal › Review article › peer-review

227 Scopus citations

Early brain magnetic resonance imaging can predict short and long-term outcomes after organophosphate poisoning in a rat model

Shrot, S., Tauber, M., Shiyovich, A., Milk, N., Rosman, Y., Eisenkraft, A., Kadar, T., Kassirer, M. & Cohen, Y., 1 May 2015, In: NeuroToxicology. 48, p. 206-216 11 p.

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Microstructural information from angular double-pulsed-field-gradient NMR: From model systems to nerves

Morozov, D., Bar, L., Sochen, N. & Cohen, Y., 1 Jul 2015, In: Magnetic Resonance in Medicine. 74, 1, p. 25-32 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

2014

Alginate-coated magnetic nanoparticles for noninvasive MRI of extracellular calcium

Bar-Shir, A., Avram, L., Yariv-Shoushan, S., Anaby, D., Cohen, S., Segev-Amzaleg, N., Frenkel, D., Sadan, O., Offen, D. & Cohen, Y., Jul 2014, In: NMR in Biomedicine. 27, 7, p. 774-783 10 p.

Research output: Contribution to journal › Article › peer-review

32 Scopus citations

Unique organization of solvent molecules within the hexameric capsules of pyrogallol[4]arene in solution

Guralnik, V., Avram, L. & Cohen, Y., 7 Nov 2014, In: Organic Letters. 16, 21, p. 5592-5595 4 p.

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

2013

Inferring Microstructural Information of White Matter from Diffusion MRI

Assaf, Y. & Cohen, Y., Nov 2013, Diffusion MRI: From Quantitative Measurement to In vivo Neuroanatomy: Second Edition. Elsevier Inc., p. 185-208 24 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

5 Scopus citations

Magnetic nanoparticles-based diagnostics and theranostics

Cohen, Y. & Shoushan, S. Y., Aug 2013, In: Current Opinion in Biotechnology. 24, 4, p. 672-681 10 p.

Research output: Contribution to journal › Review article › peer-review

42 Scopus citations

Measuring small compartments with relatively weak gradients by angular double-pulsed-field-gradient NMR

Morozov, D., Bar, L., Sochen, N. & Cohen, Y., Apr 2013, In: Magnetic Resonance Imaging. 31, 3, p. 401-407 7 p.

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Modeling of the diffusion MR signal in calibrated model systems and nerves

Morozov, D., Bar, L., Sochen, N. & Cohen, Y., Dec 2013, In: NMR in Biomedicine. 26, 12, p. 1787-1795 9 p.

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Potential¹²⁹Xe-NMR biosensors based on secondary and tertiary complexes of a water-soluble pillar[5]arene derivative

Adiri, T., Marciano, D. & Cohen, Y., 11 Jul 2013, In: Chemical Communications. 49, 63, p. 7082-7084 3 p.

Research output: Contribution to journal › Article › peer-review

55 Scopus citations

Q-Space diffusion MRI (QSI) of the disease progression in the spinal cords of the Long Evans shaker: Diffusion time and apparent anisotropy

Anaby, D., Duncan, I. D., Smith, C. M. & Cohen, Y., Dec 2013, In: NMR in Biomedicine. 26, 12, p. 1879-1886 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

Shemesh, Westin, and Cohen Reply

Shemesh, N., Westin, C. F. & Cohen, Y., 8 Mar 2013, In: Physical Review Letters. 110, 10, 109802.

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

Target-specific ligands and gadolinium-based complexes for imaging of dopamine receptors: Synthesis, binding affinity, and relaxivity

Zigelboim, I., Weissberg, A. & Cohen, Y., 19 Jul 2013, In: Journal of Organic Chemistry. 78, 14, p. 7001-7012 12 p.

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

The CONNECT project: Combining macro- and micro-structure

Assaf, Y., Alexander, D. C., Jones, D. K., Bizzi, A., Behrens, T. E. J., Clark, C. A., Cohen, Y., Dyrby, T. B., Huppi, P. S., Knoesche, T. R., LeBihan, D., Parker, G. J. M., Poupon, C., Anaby, D., Anwander, A., Bar, L., Barazany, D., Blumenfeld-Katzir, T., De-Santis, S. & Duclap, D. & 25 others, Figini, M., Fischi, E., Guevara, P., Hubbard, P., Hofstetter, S., Jbabdi, S., Kunz, N., Lazeyras, F., Lebois, A., Liptrot, M. G., Lundell, H., Mangin ̦ois, J. F., Dominguez, D. M., Morozov, D., Schreiber, J., Seunarine, K., Nava, S., Riffert, T., Sasson, E., Schmitt, B., Shemesh, N., Sotiropoulos, S. N., Tavor, I., Zhang, H. & Zhou, F. L., 15 Oct 2013, In: NeuroImage. 80, p. 273-282 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

110 Scopus citations

White matter maturation in the brains of Long Evans shaker myelin mutant rats by ex-vivo QSI and DTI

Anaby, D., Duncan, I. D., Smith, C. M. & Cohen, Y., Sep 2013, In: Magnetic Resonance Imaging. 31, 7, p. 1097-1104 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

2012

Accurate noninvasive measurement of cell size and compartment shape anisotropy in yeast cells using double-pulsed field gradient MR

Shemesh, N., Özarslan, E., Basser, P. J. & Cohen, Y., Feb 2012, In: NMR in Biomedicine. 25, 2, p. 236-246 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

51 Scopus citations

Diffusion NMR in Supramolecular Chemistry and Complexed Systems

Cohen, Y., Avram, L., Evan-Salem, T., Slovak, S., Shemesh, N. & Frish, L., 21 Mar 2012, Analytical Methods in Supramolecular Chemistry, Volume 1 & 2: Second Edition. Wiley-VCH, Vol. 1. p. 197-285 89 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

22 Scopus citations

Yoram Cohen

Research output

Search results