Research output per year
Research output per year
- 1 - 50 out of 74 results
Search results
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2013
Distribution and infection-related functions of bacillithiol in Staphylococcus aureus
Pöther, D. C., Gierok, P., Harms, M., Mostertz, J., Hochgräfe, F., Antelmann, H., Hamilton, C. J., Borovok, I., Lalk, M., Aharonowitz, Y. & Hecker, M., Apr 2013, In: International Journal of Medical Microbiology. 303, 3, p. 114-123 10 p.Research output: Contribution to journal › Article › peer-review
42 Scopus citations -
2011
Implications of the inability of Listeria monocytogenes EGD-e to grow anaerobically due to a deletion in the class III NrdD ribonucleotide reductase for its use as a model laboratory strain
Ofer, A., Kreft, J., Logan, D. T., Cohen, G., Borovok, I. & Aharonowitz, Y., Jun 2011, In: Journal of Bacteriology. 193, 12, p. 2931-2940 10 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Universal stress proteins are important for oxidative and acid stress resistance and growth of Listeria monocytogenes EGD-e in vitro and in vivo
Seifart Gomes, C., Izar, B., Pazan, F., Mohamed, W., Mraheil, M. A., Mukherjee, K., Billion, A., Aharonowitz, Y., Chakraborty, T. & Hain, T., 30 Sep 2011, In: PLoS ONE. 6, 9, e24965.Research output: Contribution to journal › Article › peer-review
Open Access70 Scopus citations -
2010
Staphylococcus aureus NrdH redoxin is a reductant of the class Ib ribonucleotide reductase
Rabinovitch, I., Yanku, M., Yeheskel, A., Cohen, G., Borovok, I. & Aharonowitz, Y., Oct 2010, In: Journal of Bacteriology. 192, 19, p. 4963-4972 10 p.Research output: Contribution to journal › Article › peer-review
Open Access28 Scopus citations -
2009
Diamide triggers mainly S thiolations in the cytoplasmic proteomes of Bacillus subtilis and Staphylococcus aureus
Pöther, D. C., Liebeke, M., Hochgräfe, F., Antelmann, H., Becher, D., Lalk, M., Lindequist, U., Borovok, I., Cohen, G., Aharonowitz, Y. & Hecker, M., Dec 2009, In: Journal of Bacteriology. 191, 24, p. 7520-7530 11 p.Research output: Contribution to journal › Article › peer-review
Open Access62 Scopus citations -
Functional analysis of the Streptomyces coelicolor NrdR ATP-cone domain: Role in nucleotide binding, oligomerization, and DNA interactions
Grinberg, I., Shteinberg, T., Hassan, Q., Aharonowitz, Y., Borovok, I. & Cohen, G., Feb 2009, In: Journal of Bacteriology. 191, 4, p. 1169-1179 11 p.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
Identification and characterization of gshA, a gene encoding the glutamate-cysteine ligase in the halophilic archaeon Haloferax volcanii
Malki, L., Yanku, M., Borovok, I., Cohen, G., Mevarech, M. & Aharonowitz, Y., Aug 2009, In: Journal of Bacteriology. 191, 16, p. 5196-5204 9 p.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations -
2008
Pathogenomics: An updated European Research Agenda
Demuth, A., Aharonowitz, Y., Bachmann, T. T., Blum-Oehler, G., Buchrieser, C., Covacci, A., Dobrindt, U., Emödy, L., van der Ende, A., Ewbank, J., Fernández, L. Á., Frosch, M., Portillo, F. G. D., Gilmore, M. S., Glaser, P., Goebel, W., Hasnain, S. E., Heesemann, J., Islam, K. & Korhonen, T. & 12 others, , May 2008, In: Infection, Genetics and Evolution. 8, 3, p. 386-393 8 p.Research output: Contribution to journal › Comment/debate
Open Access8 Scopus citations -
2007
NrdR controls differential expression of the Escherichia coli ribonucleotide reductase genes
Torrents, E., Grinberg, I., Gorovitz-Harris, B., Lundström, H., Borovok, I., Aharonowitz, Y., Sjöberg, B. M. & Cohen, G., Jul 2007, In: Journal of Bacteriology. 189, 14, p. 5012-5021 10 p.Research output: Contribution to journal › Article › peer-review
Open Access65 Scopus citations -
Staphylococcus aureus ArcR controls expression of the arginine deiminase operon
Makhlin, J., Kofman, T., Borovok, I., Kohler, C., Engelmann, S., Cohen, G. & Aharonowitz, Y., Aug 2007, In: Journal of Bacteriology. 189, 16, p. 5976-5986 11 p.Research output: Contribution to journal › Article › peer-review
Open Access83 Scopus citations -
2006
A sequence-based filtering method for ncRNA identification and its application to searching for riboswitch elements
Zhang, S., Borovok, I., Aharonowitz, Y., Sharan, R. & Bafna, V., 15 Jul 2006, In: Bioinformatics. 22, 14, p. e557-e565Research output: Contribution to journal › Article › peer-review
Open Access29 Scopus citations -
Coenzyme B12 controls transcription of the Streptomyces class Ia ribonucleotide reductase nrdABS operon via a riboswitch mechanism
Borovok, I., Gorovitz, B., Schreiber, R., Aharonowitz, Y. & Cohen, G., Apr 2006, In: Journal of Bacteriology. 188, 7, p. 2512-2520 9 p.Research output: Contribution to journal › Article › peer-review
Open Access43 Scopus citations -
The Streptomyces NrdR transcriptional regulator is a Zn ribbon/ATP cone protein that binds to the promoter regions of class Ia and class II ribonucleotide reductase operons
Grinberg, I., Shteinberg, T., Gorovitz, B., Aharonowitz, Y., Cohen, G. & Borovok, I., Nov 2006, In: Journal of Bacteriology. 188, 21, p. 7635-7644 10 p.Research output: Contribution to journal › Article › peer-review
Open Access41 Scopus citations -
2005
A multidomain fusion protein in Listeria monocytogenes catalyzes the two primary activities for glutathione biosynthesis
Gopal, S., Borovok, I., Ofer, A., Yanku, M., Cohen, G., Goebel, W., Kreft, J. & Aharonowitz, Y., Jun 2005, In: Journal of Bacteriology. 187, 11, p. 3839-3847 9 p.Research output: Contribution to journal › Article › peer-review
Open Access98 Scopus citations -
2004
Alternative oxygen-dependent and oxygen-independent ribonucleotide reductases in Streptomyces: Cross-regulation and physiological role in response to oxygen limitation
Borovok, I., Gorovitz, B., Yanku, M., Schreiber, R., Gust, B., Chater, K., Aharonowitz, Y. & Cohen, G., Nov 2004, In: Molecular Microbiology. 54, 4, p. 1022-1035 14 p.Research output: Contribution to journal › Article › peer-review
Open Access39 Scopus citations -
Role of a Cysteine Synthase in Staphylococcus aureus
Lithgow, J. K., Hayhurst, E. J., Cohen, G., Aharonowitz, Y. & Foster, S. J., Mar 2004, In: Journal of Bacteriology. 186, 6, p. 1579-1590 12 p.Research output: Contribution to journal › Article › peer-review
Open Access94 Scopus citations -
Transcriptional Regulation of the Staphylococcus aureus Thioredoxin and Thioredoxin Reductase Genes in Response to Oxygen and Disulfide Stress
Uziel, O., Borovok, I., Schreiber, R., Cohen, G. & Aharonowitz, Y., Jan 2004, In: Journal of Bacteriology. 186, 2, p. 326-334 9 p.Research output: Contribution to journal › Article › peer-review
Open Access128 Scopus citations -
2002
Streptomyces spp. contain class Ia and class II ribonucleotide reductases: Expression analysis of the genes in vegetative growth
Borovok, I., Kreisberg-Zakarin, R., Yanko, M., Schreiber, R., Myslovati, M., Åslund, F., Holmgren, A., Cohen, G. & Aharonowitz, Y., 2002, In: Microbiology. 148, 2, p. 391-404 14 p.Research output: Contribution to journal › Article › peer-review
Open Access27 Scopus citations -
2001
Analysis of transcription of the Staphylococcus aureus aerobic class Ib and anaerobic class III ribonucleotide reductase genes in response to oxygen
Masalha, M., Borovok, I., Schreiber, R., Aharonowitz, Y. & Cohen, G., 2001, In: Journal of Bacteriology. 183, 24, p. 7260-7272 13 p.Research output: Contribution to journal › Article › peer-review
Open Access109 Scopus citations -
Bacterial thiol-disulfide redox metabolism: A new target for rational drug design
Cohen, G., Borovok, I., Uziel, O., Schreiber, R. & Aharonowitz, Y., 2001, In: Periodicum Biologorum. 103, 2, p. 153-155 3 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Defining the disulphide stress response in Streptomyces coelicolor A3(2): Identification of the σR regulon
Paget, M. S. B., Molle, V., Cohen, G., Aharonowitz, Y. & Buttner, M. J., 2001, In: Molecular Microbiology. 42, 4, p. 1007-1020 14 p.Research output: Contribution to journal › Article › peer-review
168 Scopus citations -
Excretion of a phosphorus-containing carbohydrate by Streptomyces sp. A50
Ben-Bashat, D., Meller, Y., Aharonowitz, Y., Gutnick, D., Carmeli, S. & Navon, G., Dec 2001, In: Journal of Natural Products. 64, 12, p. 1538-1540 3 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Glutathione is a target in tellurite toxicity and is protected by tellurite resistance determinants in Escherichia coli
Turner, R. J., Aharonowitz, Y., Weiner, J. H. & Taylor, D. E., 2001, In: Canadian Journal of Microbiology. 47, 1, p. 33-40 8 p.Research output: Contribution to journal › Article › peer-review
88 Scopus citations -
2000
Structure-function studies of the non-heme iron active site of isopenicillin N synthase: Some implications for catalysis
Kreisberg-Zakarin, R., Borovok, I., Yanko, M., Frolow, F., Aharonowitz, Y. & Cohen, G., 30 Aug 2000, In: Biophysical Chemistry. 86, 2-3, p. 109-118 10 p.Research output: Contribution to journal › Article › peer-review
16 Scopus citations -
1999
Recent advances in the structure and function of isopenicillin N synthase
Kreisberg-Zakarin, R., Borovok, I., Yanko, M., Aharonowitz, Y. & Cohen, G., 1999, In: Antonie van Leeuwenhoek, International Journal of General and Molecular Microbiology. 75, 1-2, p. 33-39 7 p.Research output: Contribution to journal › Review article › peer-review
17 Scopus citations -
1998
Gene organization in the trxA/B-oriC region of the Streptomyces coelicolor chromosome and comparison with other eubacteria
Gal-Mor, O., Borovok, I., Av-Gay, Y., Cohen, G. & Aharonowitz, Y., 14 Sep 1998, In: Gene. 217, 1-2, p. 83-90 8 p.Research output: Contribution to journal › Article › peer-review
19 Scopus citations -
1997
Inhibition by polyphosphate of phytopathogenic polygalacturonases from Botrytis cinerea
Meller-Harel, Y., Argaman, A., Ben-Bashat, D., Navon, G., Aharonowitz, Y. & Gutnick, D., 1997, In: Canadian Journal of Microbiology. 43, 9, p. 835-840 6 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
The glutamine ligand in the ferrous iron active site of isopenicillin N synthase of Streptomyces jumonjinensis is not essential for catalysis
Landman, O., Borovok, I., Aharonowitz, Y. & Cohen, G., 24 Mar 1997, In: FEBS Letters. 405, 2, p. 172-174 3 p.Research output: Contribution to journal › Article › peer-review
31 Scopus citations -
The thioredoxin reductase system of mycoplasmas
Ben-Menachem, G., Himmelreich, R., Herrmann, R., Aharonowitz, Y. & Rottem, S., Jun 1997, In: Microbiology. 143, 6, p. 1933-1940 8 p.Research output: Contribution to journal › Article › peer-review
Open Access31 Scopus citations -
1996
Distribution of thiols in microorganisms: Mycothiol is a major thiol in most actinomycetes
Newton, G. L., Arnold, K., Price, M. S., Sherrill, C., Delcardayre, S. B., Aharonowitz, Y., Cohen, G., Davies, J., Fahey, R. C. & Davis, C., Apr 1996, In: Journal of Bacteriology. 178, 7, p. 1990-1995 6 p.Research output: Contribution to journal › Article › peer-review
Open Access473 Scopus citations -
Ferrous active site of isopenicillin N synthase: Genetic and sequence analysis of the endogenous ligands
Borovok, I., Landman, O., Kreisberg-Zakarin, R., Aharonowitz, Y. & Cohen, G., 13 Feb 1996, In: Biochemistry. 35, 6, p. 1981-1987 7 p.Research output: Contribution to journal › Article › peer-review
68 Scopus citations -
1995
The Structure of U17 Isolated from Streptomyces clavuligerus and its Properties as an Antioxidant Thiol
Newton, G. L., Bewley, C. A., Dwyer, T. J., Horn, R., Aharonowitz, Y., Cohen, G., Davies, J., Faulkner, D. J. & Fahey, R. C., Jun 1995, In: European Journal of Biochemistry. 230, 2, p. 821-825 5 p.Research output: Contribution to journal › Article › peer-review
Open Access118 Scopus citations -
1994
The thioredoxin system of Penicillium chrysogenum and its possible role in penicillin biosynthesis
Cohen, G., Argaman, A., Schreiber, R., Mislovati, M. & Aharonowitz, Y., 1994, In: Journal of Bacteriology. 176, 4, p. 973-984 12 p.Research output: Contribution to journal › Article › peer-review
Open Access56 Scopus citations -
1993
Characterization of a broad-range disulfide reductase from Streptomyces clavuligerus and its possible role in β-lactam antibiotic biosynthesis
Aharonowitz, Y., Av-Gay, Y., Schreiber, R. & Cohen, G., 1993, In: Journal of Bacteriology. 175, 3, p. 623-629 7 p.Research output: Contribution to journal › Article › peer-review
Open Access27 Scopus citations -
Low-molecular-weight thiols in streptomycetes and their potential role as antioxidants
Newton, G. L., Fahey, R. C., Cohen, G. & Aharonowitz, Y., 1993, In: Journal of Bacteriology. 175, 9, p. 2734-2742 9 p.Research output: Contribution to journal › Article › peer-review
Open Access82 Scopus citations -
Review
Aharonowitz, Y., Bergmeyer, J., Cantoral, J. M., Cohen, G., Demain, A. L., Fink, U., Kinghorn, J., Kleinkauf, H., MacCabe, A., Palissa, H., Pfeifer, E., Schwecke, T., van Liempt, H., von Döhren, H., Wolfe, S. & Zhang, J., Jul 1993, In: Bio/Technology. 11, 7, p. 807-810 4 p.Research output: Contribution to journal › Article › peer-review
65 Scopus citations -
Thioredoxin-thioredoxin reductase system of Streptomyces clavuligerus: Sequences, expression, and organization of the genes
Cohen, G., Yanko, M., Mislovati, M., Argaman, A., Schreiber, R., Av-Gay, Y. & Aharonowitz, Y., 1993, In: Journal of Bacteriology. 175, 16, p. 5159-5167 9 p.Research output: Contribution to journal › Article › peer-review
Open Access32 Scopus citations -
1992
Enzymatic characterisation of the multifunctional enzyme δ‐(l‐α‐aminoadipyl)‐l‐cysteinyl‐d‐valine synthetase from Streptomyces clavuligerus
SCHWECKE, T., AHARONOWITZ, Y., PALISSA, H., von DÖHREN, H., KLEINKAUF, H. & van LIEMPT, H., Apr 1992, In: European Journal of Biochemistry. 205, 2, p. 687-694 8 p.Research output: Contribution to journal › Article › peer-review
Open Access38 Scopus citations -
Penicillin and cephalosporin biosynthetic genes: Structure, organization, regulation, and evolution
Aharonowitz, Y., Cohen, G. & Martin, J. F., 1992, In: Annual Review of Microbiology. 46, p. 461-495 35 p.Research output: Contribution to journal › Review article › peer-review
213 Scopus citations -
Streptomyces contain a 7.0 KDa cold shock like protein
Av-gay, Y., Aharonowitz, Y. & Cohen, G., 25 Oct 1992, In: Nucleic Acids Research. 20, 20, p. 5478 1 p.Research output: Contribution to journal › Article › peer-review
Open Access36 Scopus citations -
1991
High level expression in Escherichia coli of isopenicillin N synthase genes from Flavobacterium and Streptomyces, and recovery of active enzyme from inclusion bodies
Landman, O., Shiffman, D., Av-Gay, Y., Aharonowitz, Y. & Cohen, G., 1 Dec 1991, In: FEMS Microbiology Letters. 84, 3, p. 239-244 6 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
1990
Continuous stereospecific Δ4-3-keto-steroid reduction by PAAH bead-entrapped Clostridium paraputrificum cells
Abramov, S., Aharonowitz, Y., Harnik, M., Lamed, R. & Freeman, A., Dec 1990, In: Enzyme and Microbial Technology. 12, 12, p. 982-988 7 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
Evolution of isopenicillin N synthase genes may have involved horizontal gene transfer
Landan, G., Cohen, G., Aharonowitz, Y., Shuali, Y., Graur, D. & Shiffman, D., 1990, In: Molecular Biology and Evolution. 7, 5, p. 399-406 8 p.Research output: Contribution to journal › Article › peer-review
51 Scopus citations -
Microbial isopenicillin N synthase genes: Structure, function, diversity and evolution
Cohen, G., Shiffman, D., Mevarech, M. & Aharonowitz, Y., 1990, In: Trends in Biotechnology. 8, C, p. 105-111 7 p.Research output: Contribution to journal › Article › peer-review
44 Scopus citations -
Nucleotide sequence of the isopenicillin N synthase gene (pcbC) of the gram negative Flavobacterium sp. SC 12,154
Shiffman, D., Cohen, G., Aharonowitz, Y., Palissa, H., von Dohren, H., Kieinkauf, H. & Mevarech, M., 11 Feb 1990, In: Nucleic Acids Research. 18, 3, p. 660 1 p.Research output: Contribution to journal › Comment/debate
Open Access16 Scopus citations -
1988
Cloning and comparative sequence analysis of the gene coding for isopenicillin N synthase in Streptomyces
Shiffman, D., Mevarech, M., Jensen, S. E., Cohen, G. & Aharonowitz, Y., Nov 1988, In: Molecular Genetics and Genomics. 214, 3, p. 562-569 8 p.Research output: Contribution to journal › Article › peer-review
40 Scopus citations -
Cloning and nucleotide sequence determination of the isopenicillin N synthetase gene from Streptomyces clavuligerus
Leskiw, B. K., Aharonowitz, Y., Mevarech, M., Wolfe, S., Vining, L. C., Westlake, D. W. S. & Jensen, S. E., 29 Feb 1988, In: Gene. 62, 2, p. 187-196 10 p.Research output: Contribution to journal › Article › peer-review
64 Scopus citations -
Cosolvent effect on Δ1-steroid-reductase activity of free and PAAH entrapped Mycobacterium Sp. NRRL B-3805 cells
Granot, I., Aharonowitz, Y. & Freeman, A., Feb 1988, In: Applied Microbiology and Biotechnology. 27, 5-6, p. 457-463 7 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Isolation and characterization of a linear DNA plasmid from Streptomyces clavuligerus
Keen, C. L., Mendelovitz, S., Cohen, G., Aharonowitz, Y. & Roy, K. L., Apr 1988, In: Molecular Genetics and Genomics. 212, 1, p. 172-176 5 p.Research output: Contribution to journal › Article › peer-review
35 Scopus citations -
1987
Cephamycin production and isopenicillin N synthetase activity in cultures of Streptomyces clavuligerus
Vining, L. C., Jensen, S. E., Westlake, D. W. S., Aharonowitz, Y. & Wolfe, S., Dec 1987, In: Applied Microbiology and Biotechnology. 27, 3, p. 240-246 7 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations