Yael Anne Leshem

2025

Association of Adult Atopic Dermatitis with Impaired Oral Health and Oral Dysbiosis: A Case-Control Study

Shahin, A., Leshem, Y. A., Taieb, Y., Baum, S., Barzilai, A., Jeddah, D., Sharon, E., Koren, O., Tzach-Nahman, R., Coppenhagen-Glazer, S., Hazan, R., Houri-Haddad, Y. & Greenberger, S., Feb 2025, In: International Dental Journal. 75, 1, p. 279-287 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

International consensus on methotrexate dosing for patients with atopic dermatitis: An eDelphi study

the MTX Consensus for AD Survey Study Group, Feb 2025, In: Journal of the European Academy of Dermatology and Venereology. 39, 2, p. 331-339 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

2024

A practical guide to using oral Janus kinase inhibitors for atopic dermatitis from the International Eczema Council

Haag, C., Alexis, A., Aoki, V., Bissonnette, R., Blauvelt, A., Chovatiya, R., Cork, M. J., Danby, S. G., Eichenfield, L. F., Eyerich, K., Gooderham, M., Guttman-Yassky, E., Hijnen, D. J., Irvine, A. D., Katoh, N., Murrell, D. F., Leshem, Y. A., Levin, A. A., Vittrup, I. & Olydam, J. I. & 11 others, Orfali, R. L., Paller, A. S., Renert-Yuval, Y., Rosmarin, D., Silverberg, J. I., Thyssen, J. P., Ständer, S., Stefanovic, N., Todd, G., Yu, J. D. & Simpson, E. L., 23 Dec 2024, In: British Journal of Dermatology. 192, 1, p. 135-143 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

How to use the Harmonising Outcome Measures for Eczema Core Outcome Set for atopic dermatitis trials: a users' guide

On behalf of the Harmonising Outcome Measures for Eczema (HOME) Initiative, Apr 2024, In: British Journal of Dermatology. 190, 4, p. 527-535 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Measuring Signs of Atopic Dermatitis in Clinical Practice: A HOME-CP Consensus Statement

Jacobson, M. E., Leshem, Y. A., Apfelbacher, C., Spuls, P. I., Gerbens, L. A. A., Thomas, K. S., Williams, H. C., Katoh, N., Howells, L., Schmitt, J., Deckert, S., Seshadri, R. & Simpson, E. L., 21 Aug 2024, In: JAMA Dermatology. 160, 8, p. 878-886 9 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

The association between atopic dermatitis and inflammatory bowel disease in adults: A cross-sectional study in a specialized atopic dermatitis clinic

Rom, H., Snir, Y., Schwartz, N., Hodak, E. & Leshem, Y. A., Jul 2024, In: Journal of the European Academy of Dermatology and Venereology. 38, 7, p. 1357-1363 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Upadacitinib Rapidly Improves Patient-Reported Outcomes in Atopic Dermatitis: 16-Week Results from Phase 3 Clinical Trials (Measure Up 1 and 2)

Simpson, E. L., Prajapati, V. H., Leshem, Y. A., Chovatiya, R., de Bruin-Weller, M. S., Ständer, S., Pink, A. E., Calimlim, B. M., Lee, W. J., Teixeira, H., Ladizinski, B., Hu, X., Yang, Y., Liu, Y., Liu, M., Grada, A., Platt, A. M. & Silverberg, J. I., May 2024, In: Dermatology and Therapy. 14, 5, p. 1127-1144 18 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

2023

Efficacy of dupilumab in moderate and severe atopic dermatitis

Weidinger, S., Simpson, E. L., Silverberg, J. I., Schmitt, J., Leshem, Y. A., Katoh, N., Chen, Z., Zhang, H., Shumel, B., Bansal, A., Chao, J., Lu, Y., Rossi, A. B. & Abramova, A., Jun 2023, In: JEADV Clinical Practice. 2, 2, p. 247-260 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Implementation of the HOME core outcome set for clinical trials of atopic eczema—barriers and opportunities: the HOME IX meeting report

On behalf of the Harmonising Outcome Measures for Eczema (HOME) Initiative, Nov 2023, In: Archives of Dermatological Research. 315, 9, p. 2617-2622 6 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Psychometric evaluation of the Worst Pruritus Numerical Rating Scale (NRS), Atopic Dermatitis Symptom Scale (ADerm-SS), and Atopic Dermatitis Impact Scale (ADerm-IS)

Silverberg, J. I., Leshem, Y. A., Calimlim, B. M., McDonald, J. & Litcher-Kelly, L., 2023, In: Current Medical Research and Opinion. 39, 10, p. 1289-1296 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Reporting of Harmonising Outcome Measures for Eczema (HOME) core outcome set instruments in randomized clinical trials for systemic treatments in atopic dermatitis

Lam, M., Spuls, P. I., Leshem, Y. A., Gerbens, L. A. A., Thomas, K. S., Arents, B., Burton, T., Flohr, C. & Drucker, A. M., Oct 2023, In: British Journal of Dermatology. 189, 4, p. 494-496 3 p.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

The Harmonising Outcome Measures for Eczema (HOME) implementation roadmap

On behalf of the Harmonising Outcome Measures for Eczema (HOME) Initiative, Dec 2023, In: British Journal of Dermatology. 189, 6, p. 710-718 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

2022

Cutaneous Comorbidities Associated with Atopic Dermatitis in Israel: A Retrospective Real-World Data Analysis

Leshem, Y. A., Sugerman, P. B., Weil, C., Chodick, G., Liang, H., Wang, H., Calimlim, B., Dorfman, A., Shalev, V. & Amitai, D. B., 1 Nov 2022, In: Dermatitis. 33, 6, p. S61-S68

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

Determining Severity Strata for Three Atopic Dermatitis Patient-Reported Outcome Questionnaires: Defining Severity Score Ranges for the Worst Pruritus Numerical Rating Scale and the Atopic Dermatitis Symptom and Impact Scales (ADerm-SS and ADerm-IS)

Silverberg, J. I., Simpson, E. L., Calimlim, B. M., Litcher-Kelly, L., Li, X., Sun, X. & Leshem, Y. A., Dec 2022, In: Dermatology and Therapy. 12, 12, p. 2817-2827 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

Early rituximab treatment is associated with increased and sustained remission in pemphigus patients: A retrospective cohort of 99 patients

Nosrati, A., Mimouni, T., Hodak, E., Gdalevich, M., Oren-Shabtai, M., Levi, A., Mimouni, D. & Leshem, Y. A., May 2022, In: Dermatologic Therapy. 35, 5, e15397.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

Efficacy and safety of a thermal fractional skin rejuvenation system (Tixel) for the treatment of facial and/or scalp actinic keratoses

Oren-Shabtai, M., Sloutsky, N., Lapidoth, M., Mimouni, D., Chorny, I., Snast, I., Leshem, Y. A., Friedland, R., Hodak, E., Klein, I., Agmon, Y. & Levi, A., Sep 2022, In: Lasers in Medical Science. 37, 7, p. 2899-2905 7 p.

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Epidemiology and Economic Burden of Atopic Dermatitis: Real-World Retrospective Data from a Large Nationwide Israeli Healthcare Provider Database

Weil, C., Sugerman, P. B., Chodick, G., Liang, H., Wang, H., Calimlim, B. M., Dorfman, A., Shalev, V., Ben Amitai, D. & Leshem, Y. A., Jun 2022, In: Advances in Therapy. 39, 6, p. 2502-2514 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

14 Scopus citations

Facial demodicosis in the immunosuppressed state: a retrospective case series from a tertiary referral center

Amitay-Laish, I., Solomon-Cohen, E., Feuerman, H., Didkovsky, E., Davidovici, B., Leshem, Y. A., Pavlovsky, L., Reiter, O., Mimouni, D., Hodak, E. & Segal, R., Oct 2022, In: International Journal of Dermatology. 61, 10, p. 1245-1252 8 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Real-life experience with chlormethine gel for early-stage mycosis fungoides with emphasis on types and management of cutaneous side-effects^#

Prag Naveh, H., Amitay-Laish, I., Zidan, O., Leshem, Y. A., Sherman, S., Noyman, Y., Taieb, J., Didkovsky, E. & Hodak, E., 2022, In: Journal of Dermatological Treatment. 33, 4, p. 2364-2370 7 p.

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

The HOME Core outcome set for clinical trials of atopic dermatitis

HOME Initiative, Jun 2022, In: Journal of Allergy and Clinical Immunology. 149, 6, p. 1899-1911 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

92 Scopus citations

2021

Dermoscopic features of basal cell carcinoma and its subtypes: A systematic review

Reiter, O., Mimouni, I., Dusza, S., Halpern, A. C., Leshem, Y. A. & Marghoob, A. A., Sep 2021, In: Journal of the American Academy of Dermatology. 85, 3, p. 653-664 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

61 Scopus citations

Hidradenitis suppurativa and atopic dermatitis: A 2-way association

Sherman, S., Kridin, K., Bitan, D. T., Leshem, Y. A., Hodak, E. & Cohen, A. D., Dec 2021, In: Journal of the American Academy of Dermatology. 85, 6, p. 1473-1479 7 p.

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Prophylactic Topical Treatment for EGFR Inhibitor-Induced Papulopustular Rash: A Randomized Clinical Trial

Amitay-Laish, I., Prag-Naveh, H., Ollech, A., Davidovici, B., Leshem, Y. A., Snast, I., Popovtzer, A., Purim, O., Flex, D., David, M., Brenner, B., Ben-Aharon, I., Peled, N., Hodak, E. & Stemmer, S. M., 1 Nov 2021, In: Dermatology. 237, 6, p. 988-994 7 p.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Should we be imaging lymph nodes at initial diagnosis of early-stage mycosis fungoides? Results from the PROspective Cutaneous Lymphoma International Prognostic Index (PROCLIPI) international study*

the Cutaneous Lymphoma International Consortium (CLIC) institutions, Mar 2021, In: British Journal of Dermatology. 184, 3, p. 524-531 8 p.

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

The trichoscopic features of hair shaft anomalies induced by epidermal growth factor receptor inhibitors: A case series

Kremer, N., Martinez, H., Leshem, Y. A., Hodak, E., Zer, A., Brenner, B. & Amitay-Laish, I., Nov 2021, In: Journal of the American Academy of Dermatology. 85, 5, p. 1178-1184 7 p.

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Treatment of Pemphigus Vulgaris and Foliaceus with Adjuvant Rituximab Compared to Immunosuppression Alone: Real-Life Experience

Snast, I., Spitzer, L., Hodak, E., Levi, A., Mimouni, D. & Leshem, Y. A., Mar 2021, In: Dermatology. 237, 2, p. 179-184 6 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Treatment of Pemphigus with Rituximab: Real-Life Experience in a Cohort of 117 Patients in Israel

Nosrati, A., Hodak, E., Mimouni, T., Oren-Shabtai, M., Levi, A., Leshem, Y. A. & Mimouni, D., Apr 2021, In: Dermatology. 237, 3, p. 450-456 7 p.

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

2020

Dupilumab-induced ocular surface disease (DIOSD) in patients with atopic dermatitis: Clinical presentation, risk factors for development and outcomes of treatment with tacrolimus ointment

Nahum, Y., Mimouni, M., Livny, E., Bahar, I., Hodak, E. & Leshem, Y. A., 1 Jun 2020, In: British Journal of Ophthalmology. 104, 6, p. 776-779 4 p.

Research output: Contribution to journal › Article › peer-review

57 Scopus citations

Measuring atopic eczema symptoms in clinical practice: The first consensus statement from the Harmonising Outcome Measures for Eczema in clinical practice initiative

Harmonising Outcome Measures for Eczema (HOME) initiative, May 2020, In: Journal of the American Academy of Dermatology. 82, 5, p. 1181-1186 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

38 Scopus citations

Self-administered daylight-activated photodynamic therapy for the treatment of hand eczema: A prospective proof-of-concept study

Kremer, N., Sherman, S., Lapidoth, M., Enk, C. D., Leshem, Y. A., Mimouni, T., Dudkiewicz, D., Hodak, E. & Levi, A., 1 Nov 2020, In: Dermatologic Therapy. 33, 6, e14329.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

The effects of common over-the-counter moisturizers on skin barrier function: A randomized, observer-blind, within-patient, controlled study

Leshem, Y. A., Wong, A., McClanahan, D. & Simpson, E. L., 1 Sep 2020, In: Dermatitis. 31, 5, p. 309-315 7 p.

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

2019

Acne and obesity: A nationwide study of 600,404 adolescents

Snast, I., Dalal, A., Twig, G., Astman, N., Kedem, R., Levin, D., Erlich, Y., Leshem, Y. A., Lapidoth, M., Hodak, E. & Levi, A., Sep 2019, In: Journal of the American Academy of Dermatology. 81, 3, p. 723-729 7 p.

Research output: Contribution to journal › Article › peer-review

34 Scopus citations

Conjunctivitis in atopic dermatitis patients with and without dupilumab therapy – international eczema council survey and opinion

Thyssen, J. P., de Bruin-Weller, M. S., Paller, A. S., Leshem, Y. A., Vestergaard, C., Deleuran, M., Drucker, A. M., Foelster-Holst, R., Traidl-Hoffmann, C., Eyerich, K., Taieb, A., Su, J. C., Bieber, T., Cork, M. J., Eichenfield, L. F., Guttman-Yassky, E. & Wollenberg, A., Jul 2019, In: Journal of the European Academy of Dermatology and Venereology. 33, 7, p. 1224-1231 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

57 Scopus citations

Cutaneous presentations of omphalomesenteric duct remnant: A systematic review of the literature

Solomon-Cohen, E., Lapidoth, M., Snast, I., Ben-Amitai, D., Zidan, O., Friedland, R., Moshe, M., Mimouni, D., Leshem, Y. A., Hodak, E. & Levi, A., Nov 2019, In: Journal of the American Academy of Dermatology. 81, 5, p. 1120-1126 7 p.

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Optimization of placebo use in clinical trials with systemic treatments for atopic dermatitis: an International Eczema Council survey-based position statement

Leshem, Y. A., Bissonnette, R., Paul, C., Silverberg, J. I., Irvine, A. D., Paller, A. S., Cork, M. J. & Guttman-Yassky, E., May 2019, In: Journal of the European Academy of Dermatology and Venereology. 33, 5, p. 807-815 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

16 Scopus citations

The diagnostic accuracy of dermoscopy for basal cell carcinoma: A systematic review and meta-analysis

Reiter, O., Mimouni, I., Gdalevich, M., Marghoob, A. A., Levi, A., Hodak, E. & Leshem, Y. A., May 2019, In: Journal of the American Academy of Dermatology. 80, 5, p. 1380-1388 9 p.

Research output: Contribution to journal › Article › peer-review

113 Scopus citations

2018

Picosecond 532-nm neodymium-doped yttrium aluminum garnet laser—a promising modality for the management of verrucous epidermal nevi

Levi, A., Amitai, D. B., Mimouni, D., Leshem, Y. A., Arzi, O. & Lapidoth, M., 1 Apr 2018, In: Lasers in Medical Science. 33, 3, p. 597-601 5 p.

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Report from the fifth international consensus meeting to harmonize core outcome measures for atopic eczema/dermatitis clinical trials (HOME initiative)

Chalmers, J. R., Thomas, K. S., Apfelbacher, C., Williams, H. C., Prinsen, C. A., Spuls, P. I., Simpson, E., Gerbens, L. A. A., Boers, M., Barbarot, S., Stalder, J. F., Abuabara, K., Aoki, V., Ardeleanu, M., Armstrong, J., Bang, B., Berents, T. L., Burton, T., Butler, L. & Chubachi, T. & 49 others, Cresswell-Melville, A., DeLozier, A., Eckert, L., Eichenfield, L., Flohr, C., Futamura, M., Gadkari, A., Gjerde, E. S., van Halewijn, K. F., Hawkes, C., Howells, L., Howie, L., Humphreys, R., Ishii, H. A., Kataoka, Y., Katayama, I., Kouwenhoven, W., Langan, S. M., Leshem, Y. A., Merhand, S., Mina-Osorio, P., Murota, H., Nakahara, T., Nunes, F. P., Nygaard, U., Nygårdas, M., Ohya, Y., Ono, E., Rehbinder, E., Rogers, N. K., Romeijn, G. L. E., Schuttelaar, M. L. A., Sears, A. V., Simpson, M. A., Singh, J. A., Srour, J., Stuart, B., Svensson, Talmo, G., Talmo, H., Teixeira, H. D., Thyssen, J. P., Todd, G., Torchet, F., Volke, A., von Kobyletzki, L., Weisshaar, E., Wollenberg, A. & Zaniboni, M., May 2018, In: British Journal of Dermatology. 178, 5, p. e332-e341

Research output: Contribution to journal › Article › peer-review

Open Access

77 Scopus citations

2017

Association of bullous pemphigoid with malignancy: A systematic review and meta-analysis

Atzmony, L., Mimouni, I., Reiter, O., Leshem, Y. A., Taha, O., Gdalevich, M., Hodak, E. & Mimouni, D., Oct 2017, In: Journal of the American Academy of Dermatology. 77, 4, p. 691-699 9 p.

Research output: Contribution to journal › Article › peer-review

66 Scopus citations

Determining the incidence of Pneumocystis pneumonia in patients with autoimmune blistering diseases not receiving routine prophylaxis

Amber, K. T., Lamberts, A., Solimani, F., Agnoletti, A. F., Didona, D., Euverman, I., Cozzani, E., Yueh, L. H., Di Zenzo, G., Leshem, Y. A., Mimouni, D., Hertl, M. & Horvath, B., Nov 2017, In: JAMA Dermatology. 153, 11, p. 1137-1141 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

43 Scopus citations

Is There a Role for Opportunistic Infection Prophylaxis in Pemphigus? An Expert Survey

Leshem, Y. A., Snast, I., Friedland, R., Atzmony, L., Levi, A., Hodak, E. & Mimouni, D., 1 Feb 2017, In: American Journal of Clinical Dermatology. 18, 1, p. 127-132 6 p.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Venous thromboembolism in patients with pemphigus: A cohort study

Leshem, Y. A., Atzmony, L., Dudkiewicz, I., Hodak, E. & Mimouni, D., Aug 2017, In: Journal of the American Academy of Dermatology. 77, 2, p. 256-260 5 p.

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

2016

A systematic review of Investigator Global Assessment (IGA) in atopic dermatitis (AD) trials: Many options, no standards

Futamura, M., Leshem, Y. A., Thomas, K. S., Nankervis, H., Williams, H. C. & Simpson, E. L., 1 Feb 2016, In: Journal of the American Academy of Dermatology. 74, 2, p. 288-294 7 p.

Research output: Contribution to journal › Article › peer-review

189 Scopus citations

Report from the fourth international consensus meeting to harmonize core outcome measures for atopic eczema/dermatitis clinical trials (HOME initiative)

Chalmers, J. R., Simpson, E., Apfelbacher, C. J., Thomas, K. S., von Kobyletzki, L., Schmitt, J., Singh, J. A., Svensson, Williams, H. C., Abuabara, K., Aoki, V., Ardeleanu, M., Awici-Rasmussen, M., Barbarot, S., Berents, T. L., Block, J., Bragg, A., Burton, T., Bjerring Clemmensen, K. K. & Creswell-Melville, A. & 46 others, Dinesen, M., Drucker, A., Eckert, L., Flohr, C., Garg, M., Gerbens, L. A. A., Graff, A. L. B., Hanifin, J., Heinl, D., Humphreys, R., Ishii, H. A., Kataoka, Y., Leshem, Y. A., Marquort, B., Massuel, M. A., Merhand, S., Mizutani, H., Murota, H., Murrell, D. F., Nakahara, T., Nasr, I., Nograles, K., Ohya, Y., Osterloh, I., Pander, J., Prinsen, C., Purkins, L., Ridd, M., Sach, T., Schuttelaar, M. L. A., Shindo, S., Smirnova, J., Sulzer, A., Synnøve Gjerde, E., Takaoka, R., Vestby Talmo, H., Tauber, M., Torchet, F., Volke, A., Wahlgren, C. F., Weidinger, S., Weisshaar, E., Wollenberg, A., Yamaga, K., Zhao, C. Y. & Spuls, P. I., 1 Jul 2016, In: British Journal of Dermatology. 175, 1, p. 69-79 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access