Shoshana Bar-Nun

2020

ERdj8 governs the size of autophagosomes during the formation process

Yamamoto, Y. H., Kasai, A., Omori, H., Takino, T., Sugihara, M., Umemoto, T., Hamasaki, M., Hatta, T., Natsume, T., Morimoto, R. I., Arai, R., Waguri, S., Sato, M., Sato, K., Bar-Nun, S., Yoshimori, T., Noda, T. & Nagata, K., 3 Aug 2020, In: Journal of Cell Biology. 219, 8, e201903127.

Research output: Contribution to journal › Article › peer-review

Open Access

2018

C. elegans Eats Its Own Intestine to Make Yolk Leading to Multiple Senescent Pathologies

Ezcurra, M., Benedetto, A., Sornda, T., Gilliat, A. F., Au, C., Zhang, Q., van Schelt, S., Petrache, A. L., Wang, H., de la Guardia, Y., Bar-Nun, S., Tyler, E., Wakelam, M. J. & Gems, D., 20 Aug 2018, In: Current biology : CB. 28, 16, p. 2544-2556.e5

Research output: Contribution to journal › Article › peer-review

Open Access

2016

Water-transfer slows aging in Saccharomyces cerevisiae

Cohen, A., Weindling, E., Rabinovich, E., Nachman, I., Fuchs, S., Chuartzman, S., Gal, L., Schuldiner, M. & Bar-Nun, S., Feb 2016, In: PLoS ONE. 11, 2, e0148650.

Research output: Contribution to journal › Article › peer-review

Open Access

2015

Sir2 links the unfolded protein response and the heat shock response in a stress response network

Weindling, E. & Bar-Nun, S., 13 Feb 2015, In: Biochemical and Biophysical Research Communications. 457, 3, p. 473-478 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2014

Deteriorated stress response in stationary-phase yeast: Sir2 and Yap1 are essential for Hsf1 activation by heat shock and oxidative stress, respectively

Nussbaum, I., Weindling, E., Jubran, R., Cohen, A. & Bar-Nun, S., 30 Oct 2014, In: PLoS ONE. 9, 10, A2493.

Research output: Contribution to journal › Article › peer-review

2012

Aggregation of PolyQ Proteins Is Increased upon Yeast Aging and Affected by Sir2 and Hsf1: Novel Quantitative Biochemical and Microscopic Assays

Cohen, A., Ross, L., Nachman, I. & Bar-Nun, S., 6 Sep 2012, In: PLoS ONE. 7, 9, e44785.

Research output: Contribution to journal › Article › peer-review

Open Access

ATP Binding to p97/VCP D1 Domain Regulates Selective Recruitment of Adaptors to Its Proximal N-Domain

Chia, W. S., Chia, D. X., Rao, F., Bar Nun, S. & Geifman Shochat, S., 3 Dec 2012, In: PLoS ONE. 7, 12, e50490.

Research output: Contribution to journal › Article › peer-review

Open Access

2010

Ssz1 restores endoplasmic reticulum-associated protein degradation in cells expressing defective Cdc48-Ufd1-Npl4 complex by upregulating Cdc48

Bosis, E., Salomon, D., Ohayon, O., Sivan, G., Bar-Nun, S. & Rabinovich, E., Mar 2010, In: Genetics. 184, 3, p. 695-706 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2008

Alternative pathways of disulfide bond formation yield secretion-competent, stable and functional immunoglobulins

Elkabetz, Y., Ofir, A., Argon, Y. & Bar-Nun, S., Nov 2008, In: Molecular Immunology. 46, 1, p. 97-105 9 p.

Research output: Contribution to journal › Article › peer-review

A proteasomal ATPase contributes to dislocation of Endoplasmic Reticulum-associated Degradation (ERAD) substrates

Lipson, C., Alalouf, G., Bajorek, M., Rabinovich, E., Atir-Lande, A., Glickman, M. & Bar-Nun, S., 14 Mar 2008, In: Journal of Biological Chemistry. 283, 11, p. 7166-7175 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Endoplasmic reticulum glucosidase II is inhibited by its end products

Bosis, E., Nachliel, E., Cohen, T., Takeda, Y., Ito, Y., Bar-Nun, S. & Gutman, M., 14 Oct 2008, In: Biochemistry. 47, 41, p. 10970-10980 11 p.

Research output: Contribution to journal › Article › peer-review

2007

Distinguishing between retention signals and degrons acting in ERAD

Shapira, I., Charuvi, D., Elkabetz, Y., Hirschberg, K. & Bar-Nun, S., 15 Dec 2007, In: Journal of Cell Science. 120, 24, p. 4377-4387 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2006

Proteasome channel opening as a rate-limiting step in the ubiquitin-proteasome system

Rabinovich, E., Bajorek, M., Glickman, M. & Bar-Nun, S., 2006, In: Israel Journal of Chemistry. 46, 2, p. 219-224 6 p.

Research output: Contribution to journal › Article › peer-review

Quality control in the secretory pathway

Rabinovich, E., Bussi, D., Shapira, I., Alalouf, G., Lipson, C., Elkabetz, Y., Glickman, M., Bajorek, M. & Bar-Nun, S., Apr 2006, In: Israel Medical Association Journal. 8, 4, p. 238-242 5 p.

Research output: Contribution to journal › Article › peer-review

2005

Cysteines in C_H1 underlie retention of unassembled Ig heavy chains

Elkabetz, Y., Argon, Y. & Bar-Nun, S., 15 Apr 2005, In: Journal of Biological Chemistry. 280, 15, p. 14402-14412 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2004

Distinct steps in dislocation of luminal endoplasmic reticulum-associated degradation substrates. Roles of endoplasmic reticulum-bound p97/Cdc48p and proteasome

Elkabetz, Y., Shapira, I., Rabinovich, E. & Bar-Nun, S., 6 Feb 2004, In: Journal of Biological Chemistry. 279, 6, p. 3980-3989 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2003

Immunoglobulin light chains dictate vesicular transport-dependent and -independent routes for IgM degradation by the ubiquitin-proteasome pathway

Elkabetz, Y., Kerem, A., Tencer, L., Winitz, D., Kopito, R. R. & Bar-Nun, S., 23 May 2003, In: Journal of Biological Chemistry. 278, 21, p. 18922-18929 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2002

AAA-ATPase p97/Cdc48p, a cytosolic chaperone required for endoplasmic reticulum-associated protein degradation

Rabinovich, E., Kerem, A., Fröhlich, K. U., Diamant, N. & Bar-Nun, S., 2002, In: Molecular and Cellular Biology. 22, 2, p. 626-634 9 p.

Research output: Contribution to journal › Article › peer-review

1997

I _GM degradation in b cells: proteolysis, direct visualization and auxiliary proteins

Elkabetz, Y., Kerem, A., Fingrut, O., Penner, M., Winitz, D. & Bar-Nun, S., 1997, In: FASEB Journal. 11, 9, p. A930

Research output: Contribution to journal › Article › peer-review

I _GM Degradation in b cells: er and post-er in iitro localizations

Winitz, D., Kerem, A., Elkabetz, Y. & Bar-Nun, S., 1997, In: FASEB Journal. 11, 9, p. A930

Research output: Contribution to journal › Article › peer-review

1996

Degradation of distinct assembly forms of immunoglobulin M occurs in multiple sites in permeabilized B cells

Winitz, D., Shachar, I., Elkabetz, Y., Amitay, R., Samuelov, M. & Bar-Nun, S., 1996, In: Journal of Biological Chemistry. 271, 44, p. 27645-27651 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1994

Assemblies of free amino acids as possible prebiotic catalysts

Bar-Nun, A., Kochavi, E. & Bar-Nun, S., Aug 1994, In: Journal of Molecular Evolution. 39, 2, p. 116-122 7 p.

Research output: Contribution to journal › Article › peer-review

Thiol-reducing agents and calcium perturbants alter intracellular sorting of immunoglobulin M

Shachar, I., Rabinovich, E., Kerem, A. & Bar-Nun, S., 4 Nov 1994, In: Journal of Biological Chemistry. 269, 44, p. 27344-27350 7 p.

Research output: Contribution to journal › Article › peer-review

1993

Different assembly species of IgM are directed to distinct degradation sites along the secretory pathway

Rabinovich, E., Bar-Nun, S., Amitay, R., Shachar, I., Gur, B., Taya, M. & Haimovich, J., 1993, In: Journal of Biological Chemistry. 268, 32, p. 24145-24148 4 p.

Research output: Contribution to journal › Article › peer-review

Interrelations between assembly and secretion of recombinant human acetylcholinesterase

Kerem, A., Kronman, C., Bar-Nun, S., Shafferman, A. & Velan, B., 1993, In: Journal of Biological Chemistry. 268, 1, p. 180-184 5 p.

Research output: Contribution to journal › Article › peer-review

1992

Degradation of secretory immunoglobulin M in B lymphocytes occurs in a postendoplasmic reticulum compartment and is mediated by a cysteine protease

Amitay, R., Shachar, I., Rabinovich, E., Haimovich, J. & Bar-Nun, S., 1992, In: Journal of Biological Chemistry. 267, 29, p. 20694-20700 7 p.

Research output: Contribution to journal › Article › peer-review

Immunological evidence for eight spans in the membrane domain of 3- hydroxy-3-methylglutaryl coenzyme A reductase: Implications for enzyme degradation in the endoplasmic reticulum

Roitelman, J., Olender, E. H., Bar-Nun, S., Dunn, W. A. & Simoni, R. D., 1992, In: Journal of Cell Biology. 117, 5, p. 959-973 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Polymerization of secretory IgM in B lymphocytes is prevented by a prior targeting to a degradation pathway

Shachar, I., Amitay, R., Rabinovich, E., Haimovich, J. & Bar-Nun, S., 1992, In: Journal of Biological Chemistry. 267, 34, p. 24241-24247 7 p.

Research output: Contribution to journal › Article › peer-review

1991

Inhibition of degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in vivo by cysteine protease inhibitors

Inoue, S., Bar-Nun, S., Roitelman, J. & Simoni, R. D., 1991, In: Journal of Biological Chemistry. 266, 20, p. 13311-13317 7 p.

Research output: Contribution to journal › Article › peer-review

Involvement of calcium in the mevalonate-accelerated degradation of 3-hydroxy-3-methylglutaryl-CoA reductase

Roitelman, J., Bar-Nun, S., Inoue, S. & Simoni, R. D., 1991, In: Journal of Biological Chemistry. 266, 24, p. 16085-16091 7 p.

Research output: Contribution to journal › Article › peer-review

Post-translational regulation of IgM expression in B lymphocytes: Selective nonlysosomal degradation of assembled secretory IgM is temperature-dependent and occurs prior to the trans-golgi

Amitay, R., Bar-Nun, S., Haimovich, J., Rabinovich, E. & Shachar, I., 1991, In: Journal of Biological Chemistry. 266, 19, p. 12568-12573 6 p.

Research output: Contribution to journal › Article › peer-review

1990

The regulated degradation of 3-hydroxy-3-methylglutaryl-CoA reductase requires a short-lived protein and occurs in the endoplasmic reticulum

Chun, K. T., Bar-Nun, S. & Simoni, R. D., 1990, In: Journal of Biological Chemistry. 265, 35, p. 22004-22010 7 p.

Research output: Contribution to journal › Article › peer-review

1989

Simultaneous measurements of rates of protein de novo synthesis and its steady-state levels by immunoblotting

Oron, L. & Bar-Nun, S., Jun 1989, In: Analytical Biochemistry. 179, 2, p. 284-287 4 p.

Research output: Contribution to journal › Article › peer-review

1987

N-methylisatin-β-4',4'-diethylthiosemicarbazone, an inhibitor of moloney leukemia virus protein production: Characterization and in vitro translation of viral mRNA

Ronen, D., Sherman, L., Bar-Nun, S. & Teitz, Y., 1987, In: Antimicrobial Agents and Chemotherapy. 31, 11, p. 1798-1802 5 p.

Research output: Contribution to journal › Article › peer-review

1984

Evidence that 2-allyl-2-isopropylacetamide and phenobarbital induce the same cytochrome P-450 in cultured chick embryo hepatocytes

Oron, L. & Bar-Nun, S., 28 Dec 1984, In: Biochemical and Biophysical Research Communications. 125, 3, p. 1096-1102 7 p.

Research output: Contribution to journal › Article › peer-review

Immunological evidence for phenobarbital-stimulated synthesis of cytochrome P-450 in primary cultures of chick embryo hepatocytes

Oron, L. & Bar-Nun, S., 13 Nov 1984, In: BBA - Molecular Cell Research. 805, 3, p. 291-299 9 p.

Research output: Contribution to journal › Article › peer-review

1983

G-418, an elongation inhibitor of 80 S ribosomes

Bar-Nun, S., Shneyour, Y. & Beckmann, J. S., 13 Oct 1983, In: BBA - Gene Structure and Expression. 741, 1, p. 123-127 5 p.

Research output: Contribution to journal › Article › peer-review

1981

Mechanism of induction of cytochrome P-450 by phenobarbital

Adesnik, M., Bar-Nun, S., Maschio, F., Zunich, M., Lippman, A. & Bard, E., 1981, In: Journal of Biological Chemistry. 256, 20, p. 10340-10345 6 p.

Research output: Contribution to journal › Article › peer-review

Precursor of rat liver α_2u-globulin: Partial amino acid sequence determination of its signal peptide

Ikehara, Y., Oda, K., Rosenfeld, M. G., Bar-nun, S. & Kreibich, G., Oct 1981, In: Journal of Biochemistry. 90, 6, p. 1833-1836 4 p.

Research output: Contribution to journal › Article › peer-review

1980

[34] Chloroplast Membrane Polypeptides

Bar-Nun, S. & Ohad, I., 1 Jan 1980, In: Methods in Enzymology. 69, C, p. 363-374 12 p.

Research output: Contribution to journal › Article › peer-review

Synthesis and insertion of cytochrome P-450 into endoplasmic reticulum membranes.

Bar-Nun, S., Kreibich, G., Adesnik, M., Alterman, L., Negishi, M. & Sabatini, D. D., Feb 1980, In: Proceedings of the National Academy of Sciences of the United States of America. 77, 2, p. 965-969 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1977

Appearance and composition of chlorophyll-protein complexes I and II during chloroplast membrane biogenesis in Chlamydomonas reinhardi y-1

Bar-Nun, S., Schantz, R. & Ohad, I., 11 Mar 1977, In: Biochimica et Biophysica Acta - Bioenergetics. 459, 3, p. 451-467 17 p.

Research output: Contribution to journal › Article › peer-review

1975

Proceedings: Fractionation of photosynthetic membranes of Chlamydomonas reinhardi by preparative acrylamide gel electrophoresis in sodium dodecyl sulfate.

Bar-Nun, S., Schantz, R. & Ohad, I., Nov 1975, In: Israel Journal of Medical Sciences. 11, 11, p. 1191 1 p.

Research output: Contribution to journal › Article › peer-review

1972

Biogenesis of chloroplast membranes IX. Development of photophosphorylation and proton pump activities in greening Chlamydomonas reinhardi y-1 as measured with an open-cell preparation

Wallach, D., Bar-Nun, S. & Ohad, I., 20 Apr 1972, In: Biochimica et Biophysica Acta - Bioenergetics. 267, 1, p. 125-137 13 p.

Research output: Contribution to journal › Article › peer-review

Biogenesis of chloroplast membranes X. Changes in the photosynthetic specific activity and the relationship between the light harvesting system and photosynthetic electron transfer chain during greening of Chlamydomonas reinhardi y-1 cells

Bar-Nun, S., Wallach, D. & Ohad, I., 20 Apr 1972, In: Biochimica et Biophysica Acta - Bioenergetics. 267, 1, p. 138-148 11 p.

Research output: Contribution to journal › Article › peer-review

Shoshana Bar-Nun

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