Rami Hershkoviz

Voors, A. A., Davison, B. A., Felker, G. M., Ponikowski, P., Unemori, E., Cotter, G., Teerlink, J. R., Greenberg, B. H., Filippatos, G., Teichman, S. L., Metra, M., Teichman, S. L., Massie, B. M., Goldstein, S., Bohm, M., Francis, G., Davis, C. E., Boldueva, S., Moiseev, V. & Shogenov, Z. & 33 others, Ruda, M., Vishnevsky, A., Boyarkin, M., Simanenkov, V., Tereschenko, S., Shwartz, Y., Orlikova, O., Arkhipov, M., Libov, I., Sardinov, R., Suvorov, A., Marmor, A., Katz, A., Zimlichman, R., Omary, M., Hershkoviz, R., Goland, S., Keren, A., Aronson, D., Grzybowski, J., Musial, W., Apró, D., Lupkovics, G., Stamate, C., Salajan, A., Matei, A., Levy, P., Pang, P., Collins, S., Gupta, D., Van Mieghem, W., Muyldermans, L. & Vervoort, G., 1 Sep 2011, In: European Journal of Heart Failure. 13, 9, p. 961-967 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

102 Scopus citations

2009

The role of dendritic cells in the mechanism of action of a peptide that ameliorates lupus in murine models

Sela, U., Sharabi, A., Dayan, M., Hershkoviz, R. & Mozes, E., Sep 2009, In: Immunology. 128, 1 PART 2, p. e395-e405

Research output: Contribution to journal › Article › peer-review

Open Access

27 Scopus citations

2008

Allicin inhibits blood vessel growth and downregulates Akt phosphorylation and actin polymerization

Sela, U., Brill, A., Kalchenko, V., Dashevsky, O. & Hershkoviz, R., May 2008, In: Nutrition and Cancer. 60, 3, p. 412-420 9 p.

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

A peptide that ameliorates lupus up-regulates the diminished expression of early growth response factors 2 and 3

Sela, U., Dayan, M., Hershkoviz, R., Lider, O. & Mozes, E., 1 Feb 2008, In: Journal of Immunology. 180, 3, p. 1584-1591 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

24 Scopus citations

2006

The negative regulators Foxj1 and Foxo3a are up-regulated by a peptide that inhibits systemic lupus erythematosus-associated T cell responses

Sela, U., Dayan, M., Hershkoviz, R., Cahalon, L., Lider, O. & Mozes, E., Nov 2006, In: European Journal of Immunology. 36, 11, p. 2971-2980 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

39 Scopus citations

2005

Allicin, the active component of garlic, prevents immune-mediated, concanavalin A-induced hepatic injury in mice

Bruck, R., Aeed, H., Brazovsky, E., Noor, T. & Hershkoviz, R., Jun 2005, In: Liver International. 25, 3, p. 613-621 9 p.

Research output: Contribution to journal › Article › peer-review

69 Scopus citations

Down-regulation of stromal cell-derived factor-1α-induced T cell chemotaxis by a peptide based on the complementarity-determining region 1 of an anti-DNA autoantibody via up-regulation of TGF-β secretion

Sela, U., Hershkoviz, R., Cahalon, L., Lider, O. & Mozes, E., 1 Jan 2005, In: Journal of Immunology. 174, 1, p. 302-309 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

22 Scopus citations

Effect of Linomide on adhesion molecules, TNF-α, nitrogen oxide, and cell adhesion

Abdul-Hai, A., Hershkoviz, R., Weiss, L., Lider, O. & Slavin, S., Feb 2005, In: International Immunopharmacology. 5, 2, p. 231-239 9 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Heat shock protein 60 inhibits Th1-mediated hepatitis model via innate regulation of Th1/Th2 transcription factors and cytokines

Zanin-Zhorov, A., Bruck, R., Tal, G., Oren, S., Aeed, H., Hershkoviz, R., Cohen, I. R. & Lider, O., 15 Mar 2005, In: Journal of Immunology. 174, 6, p. 3227-3236 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

82 Scopus citations

The inhibition of autoreactive T cell functions by a peptide based on the CDR1 of an anti-DNA autoantibody is via TGF-β-mediated suppression of LFA-1 and CD44 expression and function

Sela, U., Mauermann, N., Hershkoviz, R., Zinger, H., Dayan, M., Cahalon, L., Liu, J. P., Mozes, E. & Lider, O., 1 Dec 2005, In: Journal of Immunology. 175, 11, p. 7255-7263 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

36 Scopus citations

2004

Allicin inhibits SDF-1α-induced T cell interactions with fibronectin and endothelial cells by down-regulating cytoskeleton rearrangement, Pyk-2 phosphorylation and VLA-4 expression

Sela, U., Ganor, S., Hecht, I., Brill, A., Miron, T., Rabinkov, A., Wilchek, M., Mirelman, D., Lider, O. & Hershkoviz, R., Apr 2004, In: Immunology. 111, 4, p. 391-399 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

54 Scopus citations

Allicin inhibits spontaneous and TNF-α induced secretion of proinflammatory cytokines and chemokines from intestinal epithelial cells

Lang, A., Lahav, M., Sakhnini, E., Barshack, I., Fidder, H. H., Avidan, B., Bardan, E., Hershkoviz, R., Bar-Meir, S. & Chowers, Y., Oct 2004, In: Clinical Nutrition. 23, 5, p. 1199-1208 10 p.

Research output: Contribution to journal › Article › peer-review

157 Scopus citations

CD44 and hyaluronic acid cooperate with SDF-1 in the trafficking of human CD34⁺ stem/progenitor cells to bone marrow

Avigdor, A., Goichberg, P., Shivtiel, S., Dar, A., Peled, A., Samira, S., Kollet, O., Hershkoviz, R., Alon, R., Hardan, I., Ben-Hur, H., Naor, D., Nagler, A. & Lapidot, T., 15 Apr 2004, In: Blood. 103, 8, p. 2981-2989 9 p.

Research output: Contribution to journal › Article › peer-review

448 Scopus citations

Enzymatically Quiescent Heparanase Augments T Cell Interactions with VCAM-1 and Extracellular Matrix Components under Versatile Dynamic Contexts

Sotnikov, I., Hershkoviz, R., Grabovsky, V., Ilan, N., Cahalon, L., Vlodavsky, I., Alon, R. & Lider, O., 1 May 2004, In: Journal of Immunology. 172, 9, p. 5185-5193 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

76 Scopus citations

Heparin-disaccharide affects T cells: Inhibition of NF-κB activation, cell migration, and modulation of intracellular signaling

Hecht, I., Hershkoviz, R., Shivtiel, S., Lapidot, T., Cohen, I. R., Lider, O. & Cahalon, L., Jun 2004, In: Journal of Leukocyte Biology. 75, 6, p. 1139-1146 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

31 Scopus citations

Induction of mast cell interactions with blood vessel wall components by direct contact with intact T cells or T cell membranes in vitro

Brill, A., Baram, D., Sela, U., Salamon, P., Mekori, Y. A. & Hershkoviz, R., Nov 2004, In: Clinical and Experimental Allergy. 34, 11, p. 1725-1731 7 p.

Research output: Contribution to journal › Article › peer-review

33 Scopus citations

2003

Comparison of inflammatory and neurohormonal activation in cardiogenic pulmonary edema secondary to ischemic versus nonischemic causes

Milo, O., Cotter, G., Kaluski, E., Brill, A., Blatt, A., Krakover, R., Vered, Z. & Hershkoviz, R., 15 Jul 2003, In: American Journal of Cardiology. 92, 2, p. 222-226 5 p.

Research output: Contribution to journal › Article › peer-review

88 Scopus citations

Enoxaparin induced skin necrosis

Scharf, Y. & Hershkoviz, R., Nov 2003, In: Harefuah. 142, 11, p. 742-743+807

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Fibronectin-Associated Fas Ligand Rapidly Induces Opposing and Time-Dependent Effects on the Activation and Apoptosis of T Cells

Zanin-Zhorov, A., Hershkoviz, R., Hecht, I., Cahalon, L. & Lider, O., 1 Dec 2003, In: Journal of Immunology. 171, 11, p. 5882-5889 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

14 Scopus citations

Glycine modulates cytokine secretion, inhibits hepatic damage and improves survival in a model of endotoxemia in mice

Bruck, R., Wardi, J., Aeed, H., Avni, Y., Shirin, H., Avinoach, I., Shahmurov, M. & Hershkoviz, R., 1 Aug 2003, In: Liver International. 23, 4, p. 276-282 7 p.

Research output: Contribution to journal › Article › peer-review

36 Scopus citations

Heterologous desensitization of T cell functions by CCR5 and CXCR4 ligands: Inhibition of cellular signaling, adhesion and chemotaxis

Hecht, I., Cahalon, L., Hershkoviz, R., Lahat, A., Franitza, S. & Lider, O., 1 Jan 2003, In: International Immunology. 15, 1, p. 29-38 10 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

43 Scopus citations

2002

Cutting edge: Anti-inflammatory properties of low levels of IFN-γ

Flaishon, L., Topilski, I., Shoseyov, D., Hershkoviz, R., Fireman, E., Levo, Y., Marmor, S. & Shachar, I., 15 Apr 2002, In: Journal of Immunology. 168, 8, p. 3707-3711 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

73 Scopus citations

IL-12 and IL-18 induce MAP kinase-dependent adhesion of T cells to extracellular matrix components

Ariel, A., Novick, D., Rubinstein, M., Dinarello, C. A., Lider, O. & Hershkoviz, R., 1 Jul 2002, In: Journal of Leukocyte Biology. 72, 1, p. 192-198 7 p.

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Invariant chain induces B cell maturation in a process that is independent of its chaperonic activity

Matza, D., Lantner, F., Bogoch, Y., Flaishon, L., Hershkoviz, R. & Shachar, I., 5 Mar 2002, In: Proceedings of the National Academy of Sciences of the United States of America. 99, 5, p. 3018-3023 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

62 Scopus citations

2001

Amelioration of experimental colitis by thalidomide

Kenet, G., Wardi, J., Avni, Y., Aeed, H., Shirin, H., Zaidel, L., Hershkoviz, R. & Bruck, R., 2001, In: Israel Medical Association Journal. 3, 9, p. 644-648 5 p.

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Augmentation of RANTES-induced extracellular signal-regulated kinase mediated signaling and T cell adhesion by elastase-treated fibronectin

Brill, A., Hershkoviz, R., Vaday, G. G., Chowers, Y. & Lider, O., 15 Jun 2001, In: Journal of Immunology. 166, 12, p. 7121-7127 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

16 Scopus citations

Cell surface-expressed moesin-like receptor regulates T cell interactions with tissue components and binds an adhesion-modulating IL-2 peptide generated by elastase

Ariel, A., Hershkoviz, R., Altbaum-Weiss, I., Ganor, S. & Lider, O., 1 Mar 2001, In: Journal of Immunology. 166, 5, p. 3052-3060 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

14 Scopus citations

Combinatorial signals by inflammatory cytokines and chemokines mediate leukocyte interactions with extracellular matrix

Vaday, G. G., Franitza, S., Schor, H., Hecht, I., Brill, A., Cahalon, L., Hershkoviz, R. & Lider, O., 2001, In: Journal of Leukocyte Biology. 69, 6, p. 885-892 8 p.

Research output: Contribution to journal › Article › peer-review

117 Scopus citations

Heparin and low-molecular-weight heparin (enoxaparin) significantly ameliorate experimental colitis in rats

Dotan, I., Hershkoviz, R., Karmeli, F., Brazowski, E., Peled, Y., Rachmilewitz, D. & Halpern, Z., 2001, In: Alimentary Pharmacology and Therapeutics. 15, 10, p. 1687-1697 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

23 Scopus citations

Human mast cells release metalloproteinase-9 on contact with activated T cells: Juxtacrine regulation by TNF-α

Baram, D., Vaday, G. G., Salamon, P., Drucker, I., Hershkoviz, R. & Mekori, Y. A., 1 Oct 2001, In: Journal of Immunology. 167, 7, p. 4008-4016 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

212 Scopus citations

Low-dose low-molecular weight heparin (enoxaparin) is effective as adjuvant treatment in active ulcerative colitis: An open trial

Dotan, I., Hallak, A., Arber, N., Santo, M., Alexandrowitz, A., Knaani, Y., Hershkoviz, R., Brazowski, E. & Halpern, Z., 2001, In: Digestive Diseases and Sciences. 46, 10, p. 2239-2244 6 p.

Research output: Contribution to journal › Article › peer-review

62 Scopus citations

Low Levels of IFN-γ Down-regulate the Integrin-dependent Adhesion of B Cells by Activating a Pathway That Interferes with Cytoskeleton Rearrangement

Flaishon, L., Lantner, F., Hershkoviz, R., Levo, Y. & Shachar, I., 14 Dec 2001, In: Journal of Biological Chemistry. 276, 50, p. 46701-46706 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

28 Scopus citations

Lupus-like syndrome with submassive hepatic necrosis associated with hepatitis A

Segev, A., Hadari, R., Zehavi, T., Schneider, M., Hershkoviz, R. & Mekori, Y. A., 2001, In: Journal of Gastroenterology and Hepatology (Australia). 16, 1, p. 112-114 3 p.

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Rapid and efficient homing of human CD34⁺CD38^-/lowCXCR4⁺ stem and progenitor cells to the bone marrow and spleen of NOD/SCID and NOD/SCID/B2m^null mice

Kollet, O., Spiegel, A., Peled, A., Petit, I., Byk, T., Hershkoviz, R., Guetta, E., Barkai, G., Magier, A. & Lapidot, T., 15 May 2001, In: Blood. 97, 10, p. 3283-3291 9 p.

Research output: Contribution to journal › Article › peer-review

270 Scopus citations

Regulation of T-cell interaction with fibronectin by transforming growth factor-β is associated with altered Pyk2 phosphorylation

Brill, A., Franitza, S., Lider, O. & Hershkoviz, R., 2001, In: Immunology. 104, 2, p. 149-156 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

2000

Autocrine secretion of interferon γ negatively regulates homing of immature B cells

Flaishon, L., Hershkoviz, R., Lantner, F., Lider, O., Alon, R., Levo, Y., Flavell, R. A. & Shachar, I., 6 Nov 2000, In: Journal of Experimental Medicine. 192, 9, p. 1381-1387 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

73 Scopus citations

Cytokine production and matrix metalloproteinase (MMP)-9 release by human mast cells following cell-to-cell contact with activated T cells.

Vaday, G. G., Baram, D., Salamon, P., Drucker, I., Hershkoviz, R. & Mekori, Y. A., Dec 2000, In: Israel Medical Association Journal. 2 Suppl, p. 26 1 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Diminished chemokine and cytokine-induced adhesion of CD4+T cells to extracellular matrix ligands in patients with end-stage renal failure

Zeltzer, E., Bernheim, J., Korzets, Z., Zeeli, D., Rathaus, M., Mekori, Y. A. & Hershkoviz, R., 2000, In: Israel Medical Association Journal. 2, 4, p. 282-286 5 p.

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Disaccharides generated from heparan sulphate or heparin modulate chemokine-induced T-cell adhesion to extracellular matrix

Hershkoviz, R., Schor, H., Ariel, A., Hecht, I., Cohen, I. R., Lider, O. & Cahalon, L., 2000, In: Immunology. 99, 1, p. 87-93 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

23 Scopus citations

Extracellular K⁺ and opening of voltage-gated potassium channels activate T cell integrin function: Physical and functional association between Kv1.3 channels and β1 integrins

Levite, M., Cahalon, L., Peretz, A., Hershkoviz, R., Sobko, A., Ariel, A., Desai, R., Attali, B. & Lider, O., 3 Apr 2000, In: Journal of Experimental Medicine. 191, 7, p. 1167-1176 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

197 Scopus citations

Fibronectin-bound TNF-α stimulates monocyte matrix metalloproteinase-9 expression and regulates chemotaxis

Vaday, G. G., Hershkoviz, R., Rahat, M. A., Lahat, N., Cahalon, L. & Lider, O., 2000, In: Journal of Leukocyte Biology. 68, 5, p. 737-747 11 p.

Research output: Contribution to journal › Article › peer-review

65 Scopus citations

Induction of interactions between CD44 and hyaluronic acid by a short exposure of human T cells to diverse pro-inflammatory mediators

Ariel, A., Lider, O., Brill, A., Cahalon, L., Savion, N., Varon, D. & Hershkoviz, R., 2000, In: Immunology. 100, 3, p. 345-351 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

43 Scopus citations

Non-peptidic analogs of the cell adhesion motif RGD prevent experimental liver injury

Bruck, R., Hershkoviz, R., Lider, O., Shirin, H., Aeed, H. & Halpern, Z., 2000, In: Israel Medical Association Journal. 2, SUPPL. JULY, p. 74-80 7 p.

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

TNF-α associated with extracellular matrix fibronectin provides a stop signal for chemotactically migrating T cells

Franitza, S., Hershkoviz, R., Kam, N., Lichtenstein, N., Vaday, G. G., Alon, R. & Lider, O., 1 Sep 2000, In: Journal of Immunology. 165, 5, p. 2738-2747 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

72 Scopus citations

1999

Specific inhibition of T-cell adhesion to extracellular matrix and proinflammatory cytokine secretion by human recombinant galectin-1

Rabinovich, G. A., Ariel, A., Hershkoviz, R., Hirabayashi, J., Kasai, K. I. & Lider, O., 1999, In: Immunology. 97, 1, p. 100-106 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

182 Scopus citations

Rami Hershkoviz

Research output

Search results