Research output per year
Research output per year
- 1 - 50 out of 273 results
Search results
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2025
BECC-engineered live-attenuated Shigella vaccine candidates display reduced endotoxicity with robust immunogenicity in mice
Sherman, M. E., Michalski, J., Das, S., Yang, H., Chandrasekaran, L., O'Meara, T. R., Dowling, D. J., Levy, O., Barnoy, S., Venkatesan, M. & Ernst, R. K., 19 Mar 2025, In: Vaccine. 50, 126779.Research output: Contribution to journal › Article › peer-review
Open Access -
Biomarkers of vaccine safety and efficacy in vulnerable populations: Lessons from the fourth international precision vaccines conference
On behalf of IPVC 2023 Speakers' group, 1 Jan 2025, In: Vaccine. 43, 126477.Research output: Contribution to journal › Article › peer-review
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Correction to: Respiratory infection- and asthma-prone, low vaccine responder children demonstrate distinct mononuclear cell DNA methylation pathways (Clinical Epigenetics, (2024), 16, 1, (85), 10.1186/s13148-024-01703-0)
in association with the IDEAL Consortium, Dec 2025, In: Clinical Epigenetics. 17, 1, 53.Research output: Contribution to journal › Comment/debate
Open Access -
Fostering Collaboration Across Nations: Report of the 6th International Neonatal and Maternal Immunization Symposium (INMIS), Costa Rica, 2024
Muñoz, F. M., Avila Aguero, M. L., Cutland, C. L., Dinleyici, E. C., Eckert, L. O., Giles, M. L., Holder, B., Jones, C. E., Kampmann, B., Kollman, T. R., Levy, O., Marchant, A., Maertens, K., Marshall, H. S., Sadarangani, M., Gutierrez, R. U., Van Damme, P. & Heath, P. T., 1 Feb 2025, In: Pediatric Infectious Disease Journal. 44, 2, p. S2-S8Research output: Contribution to journal › Article › peer-review
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Host-microbe multiomic profiling identifies distinct COVID-19 immune dysregulation in solid organ transplant recipients
IMPACC Network, Dec 2025, In: Nature Communications. 16, 1, 586.Research output: Contribution to journal › Article › peer-review
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Network analysis reveals protein modules associated with childhood respiratory diseases
Prince, N., Begum, S., Mendez, K. M., Ramirez, L. G., Chen, Y., Chen, Q., Chu, S. H., Kachroo, P., Levy, O., Diray-Arce, J., Palma, P., Litonjua, A. A., Weiss, S. T., Kelly, R. S. & Lasky-Su, J. A., 2025, (Accepted/In press) In: Journal of Allergy and Clinical Immunology.Research output: Contribution to journal › Article › peer-review
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Pre-vaccination immune markers predict response to BNT162b2 mRNA vaccine in vulnerable groups – The CONVERS project, report from a pediatric tertiary hospital
CONVERS Study Team, 7 Mar 2025, In: Vaccine. 49, 126778.Research output: Contribution to journal › Article › peer-review
Open Access -
Product and trial design considerations on the path towards a vaccine to combat opioid overdose
Angelidou, A., Koster, J. A., Sherman, A. C., McLoughlin, C., Lalwani, P., Kelly, A., Saeed, A., McEnaney, K., Baden, L. R., Brogna, M., Weitzman, E. R., Levy, S., Dowling, D. J. & Levy, O., Dec 2025, In: npj Vaccines. 10, 1, 35.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Social complexity of a fentanyl vaccine to prevent opioid overdose conference proceedings: Radcliffe Institute for Advanced Study conference proceedings
The Opioid Vaccine Radcliffe Conference Meeting Group, 12 Jan 2025, In: Vaccine. 44, 126324.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Vaccinology: Getting our modernization act together
Levy, O., 5 May 2025, In: Journal of Experimental Medicine. 222, 5Research output: Contribution to journal › Article › peer-review
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2024
Adjuvantation of a SARS-CoV-2 mRNA vaccine with controlled tissue-specific expression of an mRNA encoding IL-12p70
Brook, B., Duval, V., Barman, S., Speciner, L., Sweitzer, C., Khanmohammed, A., Menon, M., Foster, K., Ghosh, P., Abedi, K., Koster, J., Nanishi, E., Baden, L. R., Levy, O., VanCott, T., Micol, R. & Dowling, D. J., 24 Jul 2024, In: Science Translational Medicine. 16, 757, eadm845.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
Author Correction: Co-adjuvanting DDA/TDB liposomes with a TLR7 agonist allows for IgG2a/c class-switching in the absence of Th1 cells (npj Vaccines, (2023), 8, 1, (189), 10.1038/s41541-023-00781-0)
Zimmermann, J., van Haren, S. D., Diray-Arce, J., Adriawan, I. R., Wørzner, K., Krog, R. T., Guleed, S., Hu, T., Mortensen, R., Dietrich, J., Solbak, S. M. Ø., Levy, O., Christensen, D. & Pedersen, G. K., Dec 2024, In: npj Vaccines. 9, 1, 13.Research output: Contribution to journal › Comment/debate
Open Access -
Breastfeeding and Neonatal Age Influence Neutrophil-Driven Ontogeny of Blood Cell Populations in the First Week of Human Life
Montante, S., Ben-Othman, R., Amenyogbe, N., Angelidou, A., Van Den Biggelaar, A., Cai, B., Chen, Y., Darboe, A., Diray-Arce, J., Ford, R., Idoko, O., Lee, A., Lo, M., McEnaney, K., Malek, M., Martino, D., Masiria, G., Odumade, O. A., Pomat, W. & Shannon, C. & 9 others, , 2024, In: Journal of Immunology Research. 2024, 1117796.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Developmental Immunology and Role of Host Defenses in Fetal and Neonatal Susceptibility to Infection
Lewis, D. B., Weitkamp, J. H. & Levy, O., 1 Jan 2024, Remington and Klein's Infectious Diseases of the Fetus and Newborn Infant, Ninth Edition. Elsevier, p. 73-159.e14Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
2 Scopus citations -
DNA Methylation signatures underpinning blood neutrophil to lymphocyte ratio during first week of human life
the EPIC-HIPC consortium, Dec 2024, In: Nature Communications. 15, 1, 8167.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Early inflammation as a footprint of increased mortality risk in infants living with HIV from three African countries
EPIICAL Consortium, Dec 2024, In: Scientific Reports. 14, 1, 25792.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Editorial: Precision vaccinology for infectious diseases
Rahman, M., Adeli, M., Schellhorn, H. E., Jithesh, P. V. & Levy, O., 2024, In: Frontiers in Immunology. 15, 1400443.Research output: Contribution to journal › Editorial
Open Access1 Scopus citations -
Features of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study
IMPACC Network, IMPACC Steering Committee, Clinical Data Coordinating Center (CDCC), IMPACC Data Analysis Group, IMPACC Site Investigators, IMPACC Core Laboratory & IMPACC Clinical Study Team, Jan 2024, In: Nature Communications. 15, 1, 216.Research output: Contribution to journal › Article › peer-review
27 Scopus citations -
From hit to vial: Precision discovery and development of an imidazopyrimidine TLR7/8 agonist adjuvant formulation
Soni, D., Borriello, F., Scott, D. A., Feru, F., DeLeon, M., Brightman, S. E., Cheng, W. K., Melhem, G., Smith, J. A., Ramirez, J. C., Barman, S., Cameron, M., Kelly, A., Walker, K., Nanishi, E., van Haren, S. D., Phan, T., Qi, Y., Kinsey, R. & Raczy, M. M. & 6 others, , Jul 2024, In: Science advances. 10, 27, adg3747.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Heterologous SARS-CoV-2 booster vaccine for individuals with hematological malignancies after a primary SARS-CoV-2 mRNA vaccine series
Sherman, A. C., van Haren, S. D., Borberg, E., Swank, Z., Aleissa, M., Tong, A., Rooks, R., Kanwal, U., Levine, H., Yates, B., Izaguirre, N., Ryff, K., Thomas, S., Parisi, L., Li, X., Walt, D. R., Levy, O., Walsh, S. R., Issa, N. C. & Baden, L. R., 17 Sep 2024, In: Vaccine. 42, 22, 126054.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Host-microbe multiomic profiling reveals age-dependent immune dysregulation associated with COVID-19 immunopathology
IMPACC Network, 2024, In: Science Translational Medicine. 16, 743, eadj5154.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
Human In vitro Modeling Identifies Adjuvant Combinations that Unlock Antigen Cross-presentation and Promote T-helper 1 Development in Newborns, Adults and Elders
Thomas, S., Pak, J., Doss-Gollin, S., Ryff, K., Beijnen, E., Pedersen, G. K., Christensen, D., Levy, O. & van Haren, S. D., 15 Feb 2024, In: Journal of Molecular Biology. 436, 4, 168446.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
IgM N-glycosylation correlates with COVID-19 severity and rate of complement deposition
IMPACC Data Analysis Group, IMPACC Site Investigators, IMPACC Core Laboratory, IMPACC Clinical Study Team, IMPACC Network, IMPACC Steering Committee & Clinical & Data Coordinating Center (CDCC), Dec 2024, In: Nature Communications. 15, 1, 404.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
Immune profiling of age and adjuvant-specific activation of human blood mononuclear cells in vitro
Schüller, S. S., Barman, S., Mendez-Giraldez, R., Soni, D., Daley, J., Baden, L. R., Levy, O. & Dowling, D. J., Dec 2024, In: Communications Biology. 7, 1, 709.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Integrated longitudinal multiomics study identifies immune programs associated with acute COVID-19 severity and mortality
IMPACC Network, 1 May 2024, In: Journal of Clinical Investigation. 134, 9, e17664.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Longitudinal plasma proteomic analysis of 1117 hospitalized patients with COVID-19 identifies features associated with severity and outcomes
IMPACC Network, 24 May 2024, In: Science advances. 10, 21, 5762.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Modeling human immune responses to vaccination in vitro
Morrocchi, E., van Haren, S., Palma, P. & Levy, O., Jan 2024, In: Trends in Immunology. 45, 1, p. 32-47 16 p.Research output: Contribution to journal › Review article › peer-review
14 Scopus citations -
Need for strategic communications and stakeholder engagement to advance acceptability of an overdose preventing vaccine targeting fentanyl
Weitzman, E. R., Pierce, S. E., Blakemore, L. M., Murdock, A., Angelidou, A., Dowling, D. J., Levy, O. & Levy, S., 24 Oct 2024, In: Vaccine. 42, 24, 126082.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Plasma adenosine deaminase-1 and -2 activities are lower at birth in Papua New Guinea than in The Gambia but converge over the first weeks of life
the EPIC Consortium, 2024, In: Frontiers in Immunology. 15, 1425349.Research output: Contribution to journal › Article › peer-review
Open Access -
Precision adjuvants for pediatric vaccines
Singh, A., Boggiano, C., Yin, D. E., Polakowski, L., Majji, S. P., Leitner, W. W., Levy, O. & De Paris, K., 4 Sep 2024, In: Science Translational Medicine. 16, 763, eabq7378.Research output: Contribution to journal › Short survey › peer-review
1 Scopus citations -
Predictive gene expression signature diagnoses neonatal sepsis before clinical presentation
EPIC Consortium, Dec 2024, In: EBioMedicine. 110, 105411.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Protocol for measuring anti-fentanyl antibodies in mouse serum by enzyme-linked immunosorbent assay
Koster, J. A., Prevost-Reilly, A., Soni, D., Kelly, A., Walker, K., Norton, E. B., Levy, O., Haile, C. N. & Dowling, D. J., 20 Dec 2024, In: STAR Protocols. 5, 4, 103402.Research output: Contribution to journal › Article › peer-review
Open Access -
Respiratory infection- and asthma-prone, low vaccine responder children demonstrate distinct mononuclear cell DNA methylation pathways
in association with the IDEAL Consortium, Dec 2024, In: Clinical Epigenetics. 16, 1, 85.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
The BNT162b2 mRNA vaccine demonstrates reduced age-associated TH1 support in vitro and in vivo
Brook, B., Checkervarty, A. K., Barman, S., Sweitzer, C., Bosco, A. N., Sherman, A. C., Baden, L. R., Morrocchi, E., Sanchez-Schmitz, G., Palma, P., Nanishi, E., O'Meara, T. R., McGrath, M. E., Frieman, M. B., Soni, D., van Haren, S. D., Ozonoff, A., Diray-Arce, J., Steen, H. & Dowling, D. J. & 1 others, , 15 Nov 2024, In: iScience. 27, 11, 111055.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
2023
A protocol for high-throughput screening for immunomodulatory compounds using human primary cells
Chew, K., Lee, B., Ozonoff, A., Smith, J. A., Levy, O., Dowling, D. J. & Van Haren, S., 15 Sep 2023, In: STAR Protocols. 4, 3, 102405.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
A simple, time- and cost-effective, high-throughput depletion strategy for deep plasma proteomics
Viode, A., van Zalm, P., Smolen, K. K., Fatou, B., Stevenson, D., Jha, M., Levy, O., Steen, J. & Steen, H., 29 Mar 2023, In: Science advances. 9, 13, eadf9717.Research output: Contribution to journal › Article › peer-review
Open Access38 Scopus citations -
Carbohydrate fatty acid monosulphate: oil-in-water adjuvant enhances SARS-CoV-2 RBD nanoparticle-induced immunogenicity and protection in mice
Nanishi, E., Borriello, F., Seo, H. S., O’Meara, T. R., McGrath, M. E., Saito, Y., Chen, J., Diray-Arce, J., Song, K., Xu, A. Z., Barman, S., Menon, M., Dong, D., Caradonna, T. M., Feldman, J., Hauser, B. M., Schmidt, A. G., Baden, L. R., Ernst, R. K. & Dillen, C. & 11 others, , Dec 2023, In: npj Vaccines. 8, 1, 18.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Co-adjuvanting DDA/TDB liposomes with a TLR7 agonist allows for IgG2a/c class-switching in the absence of Th1 cells
Zimmermann, J., van Haren, S. D., Arce, J., Adriawan, I. R., Wørzner, K., Krog, R. T., Guleed, S., Hu, T., Mortensen, R., Dietrich, J., Solbak, S. M. Ø., Levy, O., Christensen, D. & Pedersen, G. K., Dec 2023, In: npj Vaccines. 8, 1, 189.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Corrigendum to “Phenotypes of disease severity in a cohort of hospitalized COVID-19 patients: results from the IMPACC study” [eBioMedicine 83 (2022) 104208] (eBioMedicine (2022) 83, (S2352396422003905), (10.1016/j.ebiom.2022.104208))
the IMPACC study group members, Dec 2023, In: EBioMedicine. 98, 104860.Research output: Contribution to journal › Comment/debate
Open Access -
Early cellular and molecular signatures correlate with severity of West Nile virus infection
Lee, H. J., Zhao, Y., Fleming, I., Mehta, S., Wang, X., Wyk, B. V., Ronca, S. E., Kang, H., Chou, C. H., Fatou, B., Smolen, K. K., Levy, O., Clish, C. B., Xavier, R. J., Steen, H., Hafler, D. A., Love, J. C., Shalek, A. K., Guan, L. & Murray, K. O. & 2 others, , 15 Dec 2023, In: iScience. 26, 12, 108387.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Effective early antiretroviral therapy in perinatal-HIV infection reduces subsequent plasma inflammatory profile
on the behalf of the EPIICAL Consortium, Nov 2023, In: Pediatric Research. 94, 5, p. 1667-1674 8 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Elevated third trimester corticosteroid levels are associated with fewer offspring infections
Prince, N., Kelly, R. S., Chu, S. H., Kachroo, P., Chen, Y., Mendez, K. M., Begum, S., Bisgaard, H., Bønnelykke, K., Kim, M., Levy, O., Litonjua, A. A., Wheelock, C. E., Weiss, S. T., Chawes, B. L. & Lasky-Su, J. A., Dec 2023, In: Scientific Reports. 13, 1, 10461.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Human in vitro modeling of adjuvant formulations demonstrates enhancement of immune responses to SARS-CoV-2 antigen
Doss-Gollin, S., Thomas, S., Brook, B., Abedi, K., Lebas, C., Auderset, F., Lugo-Rodriguez, Y., Sanchez-Schmitz, G., Dowling, D. J., Levy, O. & van Haren, S. D., Dec 2023, In: npj Vaccines. 8, 1, 163.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Immunology of the Fetus and Newborn
Weitkamp, J. H., Lewis, D. B. & Levy, O., 1 Jan 2023, Avery's Diseases of the Newborn. Elsevier, p. 409-438.e8Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
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Integrative systems biology characterizes immune-mediated neurodevelopmental changes in murine Zika virus microcephaly
Fujimura, K., Guise, A. J., Nakayama, T., Schlaffner, C. N., Meziani, A., Kumar, M., Cheng, L., Vaughan, D. J., Kodani, A., Van Haren, S., Parker, K., Levy, O., Durbin, A. F., Bosch, I., Gehrke, L., Steen, H., Mochida, G. H. & Steen, J. A., 21 Jul 2023, In: iScience. 26, 7, 106909.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Multi-omic longitudinal study reveals immune correlates of clinical course among hospitalized COVID-19 patients
IMPACC Network, 20 Jun 2023, In: Cell Reports Medicine. 4, 6, 101079.Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
Precision Vaccinology Approaches for the Development of Adjuvanted Vaccines Targeted to Distinct Vulnerable Populations
Lee, B., Nanishi, E., Levy, O. & Dowling, D. J., Jun 2023, In: Pharmaceutics. 15, 6, 1766.Research output: Contribution to journal › Review article › peer-review
Open Access6 Scopus citations -
Publisher Correction: Carbohydrate fatty acid monosulphate: oil-in-water adjuvant enhances SARS-CoV-2 RBD nanoparticle-induced immunogenicity and protection in mice (npj Vaccines, (2023), 8, 1, (18), 10.1038/s41541-023-00610-4)
Nanishi, E., Borriello, F., Seo, H. S., O’Meara, T. R., McGrath, M. E., Saito, Y., Chen, J., Diray-Arce, J., Song, K., Xu, A. Z., Barman, S., Menon, M., Dong, D., Caradonna, T. M., Feldman, J., Hauser, B. M., Schmidt, A. G., Baden, L. R., Ernst, R. K. & Dillen, C. & 11 others, , Dec 2023, In: npj Vaccines. 8, 1, 30.Research output: Contribution to journal › Comment/debate
Open Access -
Reduced SARS-CoV-2 mRNA vaccine immunogenicity and protection in mice with diet-induced obesity and insulin resistance
O'Meara, T. R., Nanishi, E., McGrath, M. E., Barman, S., Dong, D., Dillen, C., Menon, M., Seo, H. S., Dhe-Paganon, S., Ernst, R. K., Levy, O., Frieman, M. B. & Dowling, D. J., Nov 2023, In: Journal of Allergy and Clinical Immunology. 152, 5, p. 1107-1120.e6Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Relationship of Heterologous Virus Responses and Outcomes in Hospitalized COVID-19 Patients
IMPACC Network, 15 Oct 2023, In: Journal of Immunology. 211, 8, p. 1224-1231 8 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations