Jacob Schachter

2024

Evaluating the core processes of a hybrid trauma-informed acceptance and commitment therapy intervention for college students

Schachter, J., Ajayi, A. A. & Delgado, J. E., Oct 2024, In: Journal of Contextual Behavioral Science. 34, 100852.

Research output: Contribution to journal › Article › peer-review

Exploring the clinical significance of specific immune-related adverse events in melanoma patients undergoing immune checkpoint inhibitor therapy

Asher, N., Bar-Hai, N., Ben-Betzalel, G., Stoff, R., Grynberg, S., Schachter, J. & Frommer-Shapira, R., 1 Oct 2024, In: Melanoma Research. 34, 5, p. 439-449 11 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Final Results for Adjuvant Dabrafenib plus Trametinib in Stage III Melanoma.

Long, G. V., Hauschild, A., Santinami, M., Kirkwood, J. M., Atkinson, V., Mandala, M., Merelli, B., Sileni, V. C., Nyakas, M., Haydon, A., Dutriaux, C., Robert, C., Mortier, L., Schachter, J., Schadendorf, D., Lesimple, T., Plummer, R., Larkin, J., Tan, M. & Adnaik, S. B. & 3 others, Burgess, P., Jandoo, T. & Dummer, R., 7 Nov 2024, In: New England Journal of Medicine. 391, 18, p. 1709-1720 12 p.

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Neoadjuvant BRAF-targeted therapy for ameloblastoma of the mandible: an organ preservation approach

Grynberg, S., Vered, M., Shapira-Frommer, R., Asher, N., Ben-Betzalel, G., Stoff, R., Steinberg, Y., Amariglio, N., Greenberg, G., Barshack, I., Toren, A., Yahalom, R., Schachter, J., Rechavi, G., Hirschhorn, A. & Abebe Campino, G., 1 Apr 2024, In: Journal of the National Cancer Institute. 116, 4, p. 539-546 8 p.

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Pembrolizumab versus ipilimumab for advanced melanoma: 10-year follow-up of the phase III KEYNOTE-006 study

Long, G. V., Carlino, M. S., McNeil, C., Ribas, A., Gaudy-Marqueste, C., Schachter, J., Nyakas, M., Kee, D., Petrella, T. M., Blaustein, A., Lotem, M., Arance, A. M., Daud, A. I., Hamid, O., Larkin, J., Yao, L., Singh, R., Lal, R. & Robert, C., 2024, (Accepted/In press) In: Annals of Oncology.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

2023

Adjuvant Therapy of Nivolumab Combined with Ipilimumab Versus Nivolumab Alone in Patients with Resected Stage IIIB-D or Stage IV Melanoma (CheckMate 915)

Weber, J. S., Schadendorf, D., Del Vecchio, M., Larkin, J., Atkinson, V., Schenker, M., Pigozzo, J., Gogas, H., Dalle, S., Meyer, N., Ascierto, P. A., Sandhu, S., Eigentler, T., Gutzmer, R., Hassel, J. C., Robert, C., Carlino, M. S., Di Giacomo, A. M., Butler, M. O. & Muñoz-Couselo, E. & 16 others, Brown, M. P., Rutkowski, P., Haydon, A., Grob, J. J., Schachter, J., Queirolo, P., De La Cruz-Merino, L., Van Der Westhuizen, A., Menzies, A. M., Re, S., Bas, T., De Pril, V., Braverman, J., Tenney, D. J., Tang, H. & Long, G. V., 20 Jan 2023, In: Journal of Clinical Oncology. 41, 3, p. 517-527 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

79 Scopus citations

Better Late Than Never: The Impact of Steroidal Treatment on the Outcome of Melanoma Patients Treated with Immunotherapy

Bar-Hai, N., Ben-Betzalel, G., Stoff, R., Grynberg, S., Schachter, J., Shapira-Frommer, R. & Asher, N., Jun 2023, In: Cancers. 15, 11, 3041.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

Health-Related Quality of Life with Pembrolizumab in Patients with Locally Advanced or Recurrent or Metastatic Cutaneous Squamous Cell Carcinoma: KEYNOTE-629

Bratland, Å., Munoz-Couselo, E., Mortier, L., Roshdy, O., González, R., Schachter, J., Arance, A. M., Grange, F., Meyer, N., Joshi, A. J., Billan, S., Hughes, B. G. M., Grob, J. J., Ramakrishnan, K., Ge, J., Gumuscu, B., Swaby, R. F. & Gutzmer, R., Dec 2023, In: Dermatology and Therapy. 13, 12, p. 3165-3180 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Incidence and Outcome of Neurologic Immune-Related Adverse Events Associated With Immune Checkpoint Inhibitors in Patients With Melanoma

Pepys, J., Stoff, R., Ramon-Gonen, R., Ben-Betzalel, G., Grynberg, S., Frommer, R. S., Schachter, J., Asher, N., Taliansky, A., Nikitin, V., Dori, A. & Shelly, S., 12 Dec 2023, In: Neurology. 101, 24, p. E2472-E2482

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

MYC Induces Immunotherapy and IFNg Resistance Through Downregulation of JAK2

Markovits, E., Harush, O., Baruch, E. N., Shulman, E. D., Debby, A., Itzhaki, O., Anafi, L., Danilevsky, A., Shomron, N., Ben-Betzalel, G., Asher, N., Shapira-Frommer, R., Schachter, J., Barshack, I., Geiger, T., Elkon, R., Besser, M. J. & Markel, G., 1 Jul 2023, In: Cancer immunology research. 11, 7, p. 909-924 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Overall survival with first-line atezolizumab in combination with vemurafenib and cobimetinib in BRAF^V600 mutation-positive advanced melanoma (IMspire150): second interim analysis of a multicentre, randomised, phase 3 study

Ascierto, P. A., Stroyakovskiy, D., Gogas, H., Robert, C., Lewis, K., Protsenko, S., Pereira, R. P., Eigentler, T., Rutkowski, P., Demidov, L., Zhukova, N., Schachter, J., Yan, Y., Caro, I., Hertig, C., Xue, C., Kusters, L., McArthur, G. A. & Gutzmer, R., Jan 2023, In: The Lancet Oncology. 24, 1, p. 33-44 12 p.

Research output: Contribution to journal › Article › peer-review

54 Scopus citations

PET-CT underestimates the true pathological extent of disease at lymphadenectomy for melanoma patients after systemic therapy

Mor, E., Schtrechman, G., Nizri, E., Shimonovitz, M., Asher, N., Ben-Betzalel, G., Grynberg, S., Stoff, R., Miodovnik, M., Adileh, M., Ben-Yaacov, A., Steinberg, Y., Shapira, R., Schachter, J., Lahat, G., Nissan, A., Zippel, D. & Laks, S., Oct 2023, In: European Journal of Surgical Oncology. 49, 10, 106950.

Research output: Contribution to journal › Article › peer-review

Real world evidence of Lenvatinib + anti PD-1 as an advanced line for metastatic melanoma

Stoff, R., Asher, N., Laks, S., Steinberg, Y., Schachter, J., Shapira-Frommer, R., Grynberg, S. & Ben-Betzalel, G., 2023, In: Frontiers in Oncology. 13, 1180988.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

Seven-Year Follow-Up of the Phase III KEYNOTE-006 Study: Pembrolizumab Versus Ipilimumab in Advanced Melanoma

Robert, C., Carlino, M. S., McNeil, C., Ribas, A., Grob, J. J., Schachter, J., Nyakas, M., Kee, D., Petrella, T. M., Blaustein, A., Lotem, M., Arance, A., Daud, A. I., Hamid, O., Larkin, J., Anderson, J., Krepler, C., Grebennik, D. & Long, G. V., 20 Aug 2023, In: Journal of Clinical Oncology. 41, 24, p. 3998-4003 6 p.

Research output: Contribution to journal › Article › peer-review

34 Scopus citations

2022

Adenosine-Deaminase-Acting-on-RNA-1 Facilitates T-cell Migration toward Human Melanoma Cells

Margolis, N., Moalem, H., Meirson, T., Galore-Haskel, G., Markovits, E., Baruch, E. N., Vizel, B., Yeffet, A., Kanterman-Rifman, J., Debby, A., Besser, M. J., Schachter, J. & Markel, G., Sep 2022, In: Cancer immunology research. 10, 9, p. 1127-1140 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

Antitumor activity of ipilimumab or BRAF ± MEK inhibition after pembrolizumab treatment in patients with advanced melanoma: analysis from KEYNOTE-006

Long, G. V., Arance, A., Mortier, L., Lorigan, P., Blank, C., Mohr, P., Schachter, J., Grob, J. J., Lotem, M., Middleton, M. R., Neyns, B., Steven, N., Ribas, A., Walpole, E., Carlino, M. S., Lebbe, C., Sznol, M., Jensen, E., Leiby, M. A. & Ibrahim, N. & 1 others, Robert, C., Feb 2022, In: Annals of Oncology. 33, 2, p. 204-215 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

Efficacy and toxicity of Ipilimumab-Nivolumab combination therapy in elderly metastatic melanoma patients

Stoff, R., Grynberg, S., Asher, N., Laks, S., Steinberg, Y., Schachter, J., Shapira-Frommer, R. & Ben-Betzalel, G., 7 Nov 2022, In: Frontiers in Oncology. 12, 1020058.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

Molecular and Functional Signatures Associated with CAR T Cell Exhaustion and Impaired Clinical Response in Patients with B Cell Malignancies

Beider, K., Itzhaki, O., Schachter, J., Grushchenko-Polaq, A. H., Voevoda-Dimenshtein, V., Rosenberg, E., Ostrovsky, O., Devillers, O., Frommer, R. S., Zeltzer, L. A., Toren, A., Jacoby, E., Shimoni, A., Avigdor, A., Nagler, A. & Besser, M. J., 1 Apr 2022, In: Cells. 11, 7, 1140.

Research output: Contribution to journal › Article › peer-review

Open Access

13 Scopus citations

Radiotherapy may augment response to immunotherapy in metastatic uveal melanoma patients

Grynberg, S., Stoff, R., Asher, N., Shapira-Frommer, R., Schachter, J., Haisraely, O., Lawrence, Y. & Ben-Betzalel, G., 2022, In: Therapeutic Advances in Medical Oncology. 14

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

The efficacy of immune checkpoint blockade for melanoma in-transit with or without nodal metastases – A multicenter cohort study

Holmberg, C. J., Ny, L., Hieken, T. J., Block, M. S., Carr, M. J., Sondak, V. K., Örtenwall, C., Katsarelias, D., Dimitriou, F., Menzies, A. M., Saw, R. P., Rogiers, A., Straker, R. J., Karakousis, G., Applewaite, R., Pallan, L., Han, D., Vetto, J. T., Gyorki, D. E. & Tie, E. N. & 25 others, Vitale, M. G., Ascierto, P. A., Dummer, R., Cohen, J., Hui, J. Y., Schachter, J., Asher, N., Helgadottir, H., Chai, H., Kroon, H., Coventry, B., Rothermel, L. D., Sun, J., Carlino, M. S., Duncan, Z., Broman, K., Weber, J., Lee, A. Y., Berman, R. S., Teras, J., Ollila, D. W., Long, G. V., Zager, J. S., van Akkooi, A. & Olofsson Bagge, R., Jul 2022, In: European Journal of Cancer. 169, p. 210-222 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

18 Scopus citations

The increasing role of abdominal metastesectomy for malignant melanoma in the era of modern therapeutics

Mor, E., Laks, S., Assaf, D., Asher, N., Ben-Betzalel, G., Grynberg, S., Stoff, R., Adileh, M., Steinberg-Silman, Y., Shapira-Frommer, R., Schachter, J., Nissan, A. & Zippel, D., Sep 2022, In: Surgical Oncology. 44, 101808.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

The Moderating and Mediating Roles of Mindfulness and Rumination on COVID-19 Stress and Depression: A Longitudinal Study of Young Adults

Schachter, J., Ajayi, A. A. & Nguyen, P. L., 23 Jun 2022, In: Journal of Counseling Psychology. 69, 5, p. 732-744 13 p.

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Tilsotolimod Exploits the TLR9 Pathway to Promote Antigen Presentation and Type 1 IFN Signaling in Solid Tumors: A Multicenter International Phase I/II Trial (ILLUMINATE-101)

Babiker, H., Borazenci, E., Subbiah, V., Agarwala, S., Algazi, A., Schachter, J., Lotem, M., Maurice-Dror, C., Hendler, D., Rahimian, S., Minderman, H., Haymaker, C., Mahadevan, D., Bernatchez, C., Murthy, R., Hultsch, R., Kaplan, N., Woodhead, G., Hennemeyer, C. & Chunduru, S. & 3 others, Anderson, P. M., Diab, A. & Puzanov, I., 1 Dec 2022, In: Clinical Cancer Research. 28, 23, p. 5079-5087 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

2021

Adjuvant pembrolizumab versus placebo in resected stage III melanoma (EORTC 1325-MG/KEYNOTE-054): health-related quality-of-life results from a double-blind, randomised, controlled, phase 3 trial

EORTC Melanoma Group, May 2021, In: The Lancet Oncology. 22, 5, p. 655-664 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

49 Scopus citations

Adjuvant pembrolizumab versus placebo in resected stage III melanoma (EORTC 1325-MG/KEYNOTE-054): distant metastasis-free survival results from a double-blind, randomised, controlled, phase 3 trial

EORTC Melanoma Group, May 2021, In: The Lancet Oncology. 22, 5, p. 643-654 12 p.

Research output: Contribution to journal › Article › peer-review

264 Scopus citations

Comparison of non-myeloablative lymphodepleting preconditioning regimens in patients undergoing adoptive T cell therapy

Nissani, A., Lev-Ari, S., Meirson, T., Jacoby, E., Asher, N., Ben-Betzalel, G., Itzhaki, O., Shapira-Frommer, R., Schachter, J., Markel, G. & Besser, M. J., 14 May 2021, In: Journal for ImmunoTherapy of Cancer. 9, 5, e001743.

Research output: Contribution to journal › Article › peer-review

Open Access

33 Scopus citations

Fecal microbiota transplant promotes response in immunotherapy-refractory melanoma patients

Baruch, E. N., Youngster, I., Ben-Betzalel, G., Ortenberg, R., Lahat, A., Katz, L., Adler, K., Dick-Necula, D., Raskin, S., Bloch, N., Rotin, D., Anafi, L., Avivi, C., Melnichenko, J., Steinberg-Silman, Y., Mamtani, R., Harati, H., Asher, N., Shapira-Frommer, R. & Brosh-Nissimov, T. & 12 others, Eshet, Y., Ben-Simon, S., Ziv, O., Khan, M. A. W., Amit, M., Ajami, N. J., Barshack, I., Schachter, J., Wargo, J. A., Koren, O., Markel, G. & Boursi, B., 5 Feb 2021, In: Science. 371, 6529, p. 602-609 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

892 Scopus citations

Genetic Modification of Tumor-Infiltrating Lymphocytes via Retroviral Transduction

Weinstein-Marom, H., Gross, G., Levi, M., Brayer, H., Schachter, J., Itzhaki, O. & Besser, M. J., 7 Jan 2021, In: Frontiers in Immunology. 11, 584148.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Health-Related Quality of Life of Patients with Recurrent or Metastatic Cutaneous Squamous Cell Carcinoma Treated with Pembrolizumab in KEYNOTE-629

Hughes, B. G. M., Mendoza, R. G., Basset-Seguin, N., Vornicova, O., Schachter, J., Joshi, A., Meyer, N., Grange, F., Piulats, J. M., Bauman, J. R., Chirovsky, D., Zhang, P., Gumuscu, B., Swaby, R. F. & Grob, J. J., Oct 2021, In: Dermatology and Therapy. 11, 5, p. 1777-1790 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

Identification of bacteria-derived HLA-bound peptides in melanoma

Kalaora, S., Nagler, A., Nejman, D., Alon, M., Barbolin, C., Barnea, E., Ketelaars, S. L. C., Cheng, K., Vervier, K., Shental, N., Bussi, Y., Rotkopf, R., Levy, R., Benedek, G., Trabish, S., Dadosh, T., Levin-Zaidman, S., Geller, L. T., Wang, K. & Greenberg, P. & 33 others, Yagel, G., Peri, A., Fuks, G., Bhardwaj, N., Reuben, A., Hermida, L., Johnson, S. B., Galloway-Peña, J. R., Shropshire, W. C., Bernatchez, C., Haymaker, C., Arora, R., Roitman, L., Eilam, R., Weinberger, A., Lotan-Pompan, M., Lotem, M., Admon, A., Levin, Y., Lawley, T. D., Adams, D. J., Levesque, M. P., Besser, M. J., Schachter, J., Golani, O., Segal, E., Geva-Zatorsky, N., Ruppin, E., Kvistborg, P., Peterson, S. N., Wargo, J. A., Straussman, R. & Samuels, Y., 1 Apr 2021, In: Nature. 592, 7852, p. 138-143 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

227 Scopus citations

Immunotherapy discontinuation in metastatic melanoma: Lessons from real-life clinical experience

Asher, N., Israeli-Weller, N., Shapira-Frommer, R., Ben-Betzalel, G., Schachter, J., Meirson, T. & Markel, G., 2 Jun 2021, In: Cancers. 13, 12, 3074.

Research output: Contribution to journal › Article › peer-review

Open Access

20 Scopus citations

Long-term outcomes in patients with advanced melanoma who had initial stable disease with pembrolizumab in KEYNOTE-001 and KEYNOTE-006

Hamid, O., Robert, C., Daud, A., Carlino, M. S., Mitchell, T. C., Hersey, P., Schachter, J., Long, G. V., Hodi, F. S., Wolchok, J. D., Arance, A., Grob, J. J., Joshua, A. M., Weber, J. S., Mortier, L., Jensen, E., Diede, S. J., Moreno, B. H. & Ribas, A., Nov 2021, In: European Journal of Cancer. 157, p. 391-402 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

18 Scopus citations

Long-term safety of pembrolizumab monotherapy and relationship with clinical outcome: A landmark analysis in patients with advanced melanoma

Robert, C., Hwu, W. J., Hamid, O., Ribas, A., Weber, J. S., Daud, A. I., Hodi, F. S., Wolchok, J. D., Mitchell, T. C., Hersey, P., Dronca, R., Joseph, R. W., Boutros, C., Min, L., Long, G. V., Schachter, J., Puzanov, I., Dummer, R., Lin, J. & Ibrahim, N. & 3 others, Diede, S. J., Carlino, M. S. & Joshua, A. M., Feb 2021, In: European Journal of Cancer. 144, p. 182-191 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

65 Scopus citations

microRNA expression patterns in tumor infiltrating lymphocytes are strongly associated with response to adoptive cell transfer therapy

Galore-Haskel, G., Greenberg, E., Yahav, I., Markovits, E., Ortenberg, R., Shapira-Fromer, R., Itzhaki, O., Schachter, J., Besser, M. J. & Markel, G., Jun 2021, In: Cancer Immunology, Immunotherapy. 70, 6, p. 1541-1555 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

Pembrolizumab for locally advanced and recurrent/metastatic cutaneous squamous cell carcinoma (KEYNOTE-629 study): an open-label, nonrandomized, multicenter, phase II trial

Hughes, B. G. M., Munoz-Couselo, E., Mortier, L., Bratland, Gutzmer, R., Roshdy, O., González Mendoza, R., Schachter, J., Arance, A., Grange, F., Meyer, N., Joshi, A., Billan, S., Zhang, P., Gumuscu, B., Swaby, R. F. & Grob, J. J., Oct 2021, In: Annals of Oncology. 32, 10, p. 1276-1285 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

103 Scopus citations

Role of tumor-infiltrating B cells in clinical outcome of patients with melanoma treated with dabrafenib plus trametinib

Brase, J. C., Walter, R. F. H., Savchenko, A., Gusenleitner, D., Garrett, J., Schimming, T., Varaljai, R., Castelletti, D., Kim, J., Dakappagari, N., Schultz, K., Robert, C., Long, G. V., Nathan, P. D., Ribas, A., Flaherty, K. T., Karaszewska, B., Schachter, J., Sucker, A. & Schmid, K. W. & 5 others, Zimmer, L., Livingstone, E., Gasal, E., Schadendorf, D. & Roesch, A., 15 Aug 2021, In: Clinical Cancer Research. 27, 16, p. 4500-4510 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

The efficacy of immunotherapy for in-transit metastases of melanoma: An analysis of randomized controlled trials

Olofsson Bagge, R., Ny, L., Ascierto, P. A., Hodi, F. S., Larkin, J., Robert, C., Schachter, J., Weber, J. S., Long, G. V. & Van Akkooi, A. C. J., 1 Apr 2021, In: Melanoma Research. 31, 2, p. 181-185 5 p.

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

2020

Association of BRAF V600E/K Mutation Status and Prior BRAF/MEK Inhibition with Pembrolizumab Outcomes in Advanced Melanoma: Pooled Analysis of 3 Clinical Trials

Puzanov, I., Ribas, A., Robert, C., Schachter, J., Nyakas, M., Daud, A., Arance, A., Carlino, M. S., O'day, S. J., Long, G. V., Margolin, K. A., Dummer, R., Schadendorf, D., Lutzky, J., Ascierto, P. A., Tarhini, A., Lin, J., Mogg, R., Homet Moreno, B. & Ibrahim, N. & 1 others, Hamid, O., Aug 2020, In: JAMA Oncology. 6, 8, p. 1256-1264 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

51 Scopus citations

Comprehensive single institute experience with melanoma TIL: Long term clinical results, toxicity profile, and prognostic factors of response

Besser, M. J., Itzhaki, O., Ben-Betzalel, G., Zippel, D. B., Zikich, D., Kubi, A., Brezinger, K., Nissani, A., Levi, M., Zeltzer, L. A., Ben-Nun, A., Asher, N., Shimoni, A., Nagler, A., Markel, G., Shapira-Frommer, R. & Schachter, J., 1 Jul 2020, In: Molecular Carcinogenesis. 59, 7, p. 736-744 9 p.

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Five-Year Analysis of Adjuvant Dabrafenib plus Trametinib in Stage III Melanoma

Dummer, R., Hauschild, A., Santinami, M., Atkinson, V., MandalÃ, M., Kirkwood, J. M., Sileni, V. C., Larkin, J., Nyakas, M., Dutriaux, C., Haydon, A., Robert, C., Mortier, L., Schachter, J., Lesimple, T., Plummer, R., Dasgupta, K., Gasal, E., Tan, M. & Long, G. V. & 1 others, Schadendorf, D., 17 Sep 2020, In: New England Journal of Medicine. 383, 12, p. 1139-1148 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

296 Scopus citations

Gamma-Delta CAR-T Cells Show CAR-Directed and Independent Activity Against Leukemia

Rozenbaum, M., Meir, A., Aharony, Y., Itzhaki, O., Schachter, J., Bank, I., Jacoby, E. & Besser, M. J., 2 Jul 2020, In: Frontiers in Immunology. 11, 1347.

Research output: Contribution to journal › Article › peer-review

Open Access

166 Scopus citations

Head-to-head comparison of in-house produced CD19 CAR-T cell in ALL and NHL patients

Itzhaki, O., Jacoby, E., Nissani, A., Levi, M., Nagler, A., Kubi, A., Brezinger, K., Brayer, H., Zeltzer, L. A., Rozenbaum, M., Vernitsky, H., Markel, G., Toren, A., Avigdor, A., Schachter, J. & Besser, M. J., 8 Mar 2020, In: Journal for ImmunoTherapy of Cancer. 8, 1, e000148.

Research output: Contribution to journal › Article › peer-review

Open Access

37 Scopus citations

Immune co-culture cell microarray–a feasible tool for high-throughput functional investigation of lymphocyte–cancer interactions

Baruch, E. N., Ortenberg, R., Avivi, C., Anafi, L., Dick-Necula, D., Stossel, C., Moshkovits, Y., Itzhaki, O., Besser, M. J., Schachter, J., Barshack, I. & Markel, G., 1 Jan 2020, In: OncoImmunology. 9, 1, 1741267.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

KEYNOTE-022 part 3: A randomized, double-blind, phase 2 study of pembrolizumab, dabrafenib, and trametinib in BRAF-mutant melanoma

Ferrucci, P. F., Di Giacomo, A. M., Del Vecchio, M., Atkinson, V., Schmidt, H., Schachter, J., Queirolo, P., Long, G. V., Stephens, R., Svane, I. M., Lotem, M., Abu-Amna, M., Gasal, E., Ghori, R., Diede, S. J., Croydon, E. S., Ribas, A. & Ascierto, P. A., 24 Dec 2020, In: Journal for ImmunoTherapy of Cancer. 8, 2, e001806.

Research output: Contribution to journal › Article › peer-review

Open Access

130 Scopus citations

Pembrolizumab monotherapy for recurrent or metastatic cutaneous squamous cell carcinoma: A single-arm phase II trial (KEYNOTE-629)

Grob, J. J., Gonzalez, R., Basset-Seguin, N., Vornicova, O., Schachter, J., Joshi, A., Meyer, N., Grange, F., Piulats, J. M., Bauman, J. R., Zhang, P., Gumuscu, B., Swaby, R. F. & Hughes, B. G. M., 2020, In: Journal of Clinical Oncology. 38, 25, p. 2916-2925 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

185 Scopus citations

Real world outcomes of ipilimumab and nivolumab in patients with metastatic melanoma

Asher, N., Ben-Betzalel, G., Lev-Ari, S., Shapira-Frommer, R., Steinberg-Silman, Y., Gochman, N., Schachter, J., Meirson, T. & Markel, G., Aug 2020, In: Cancers. 12, 8, p. 1-18 18 p., 2329.

Research output: Contribution to journal › Article › peer-review

Open Access

45 Scopus citations

The non-responding adrenal metastasis in melanoma: The case for minimally invasive adrenalectomy in the age of modern therapies

Zippel, D., Yalon, T., Nevo, Y., Markel, G., Asher, N., Schachter, J., Goitein, D., Segal, T. A., Nissan, A. & Hazzan, D., Aug 2020, In: American Journal of Surgery. 220, 2, p. 349-353 5 p.

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

2019

An open-label, multicentre safety study of vemurafenib in patients with BRAF^V600-mutant metastatic melanoma: final analysis and a validated prognostic scoring system

Larkin, J., Brown, M. P., Arance, A. M., Hauschild, A., Queirolo, P., Vecchio, M. D., Ascierto, P. A., Krajsová, I., Schachter, J., Neyns, B., Garbe, C., Sileni, V. C., Mandalà, M., Gogas, H., Espinosa, E., Hospers, G., Lorigan, P., Nyakas, M., Guminski, A. & Liszkay, G. & 5 others, Rutkowski, P., Miller, W., Donica, M., Makrutzki, M. & Blank, C., Jan 2019, In: European Journal of Cancer. 107, p. 175-185 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

13 Scopus citations

Dabrafenib, trametinib and pembrolizumab or placebo in BRAF-mutant melanoma

Ascierto, P. A., Ferrucci, P. F., Fisher, R., Del Vecchio, M., Atkinson, V., Schmidt, H., Schachter, J., Queirolo, P., Long, G. V., Di Giacomo, A. M., Svane, I. M., Lotem, M., Bar-Sela, G., Couture, F., Mookerjee, B., Ghori, R., Ibrahim, N., Moreno, B. H. & Ribas, A., 1 Jun 2019, In: Nature Medicine. 25, 6, p. 941-946 6 p.

Research output: Contribution to journal › Article › peer-review

248 Scopus citations

Early and late hematologic toxicity following CD19 CAR-T cells

Fried, S., Avigdor, A., Bielorai, B., Meir, A., Besser, M. J., Schachter, J., Shimoni, A., Nagler, A., Toren, A. & Jacoby, E., 1 Oct 2019, In: Bone Marrow Transplantation. 54, 10, p. 1643-1650 8 p.

Research output: Contribution to journal › Article › peer-review

291 Scopus citations

Jacob Schachter

Research output

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