Research output per year
Research output per year
- 1 - 50 out of 53 results
Search results
-
2024
NLRP3 Deficiency in Nonimmune Cells Averts Obesity-Induced Fatty Liver Disease
Margalit Grigg, L., Abu Shrkihe, B., Efimova, I., Solodeev, I., Shteingard, Y., Shani, N., Zvibel, I. & Varol, C., Feb 2024, In: Laboratory Investigation. 104, 2, 100308.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Sortilin in Biliary Epithelial Cells Promotes Ductular Reaction and Fibrosis during Cholestatic Injury
Hubel, E., Neumann, A., Fishman, S., Schaffer, O., Erez, N., Shrkihe, B. A., Shteingard, Y., Gross, T., Shibolet, O., Varol, C. & Zvibel, I., Jun 2024, In: American Journal of Pathology. 194, 6, p. 941-957 17 p.Research output: Contribution to journal › Article › peer-review
-
2021
GIPR Signaling in Immune Cells Maintains Metabolically Beneficial Type 2 Immune Responses in the White Fat From Obese Mice
Efimova, I., Steinberg, I., Zvibel, I., Neumann, A., Mantelmacher, D. F., Drucker, D. J., Fishman, S. & Varol, C., 25 Feb 2021, In: Frontiers in Immunology. 12, 643144.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Repetitive amiodarone administration causes liver damage via adipose tissue ER stress-dependent lipolysis, leading to hepatotoxic free fatty acid accumulation
Hubel, E., Fishman, S., Holopainen, M., Kakel, R., Shaffer, O., Houri, I., Zvibel, I. & Shibolet, O., 2021, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 321, 3, p. G298-G307Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
2019
GIP regulates inflammation and body weight by restraining myeloid-cell-derived S100A8/A9
Mantelmacher, F. D., Zvibel, I., Cohen, K., Epshtein, A., Pasmanik-Chor, M., Vogl, T., Kuperman, Y., Weiss, S., Drucker, D. J., Varol, C. & Fishman, S., 1 Jan 2019, In: Nature Metabolism. 1, 1, p. 58-69 12 p.Research output: Contribution to journal › Article › peer-review
44 Scopus citations -
Incretin Hormones in the Control of Immunometabolism
Fishman, S., Zvibel, I. & Varol, C., 5 Jun 2019, In: Immunometabolism (United States). 1, 1, e190004.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
2017
Glucose-dependent insulinotropic polypeptide receptor deficiency leads to impaired bone marrow hematopoiesis
Mantelmacher, F. D., Fishman, S., Cohen, K., Chor, M. P., Yamada, Y., Zvibel, I. & Varol, C., 15 Apr 2017, In: Journal of Immunology. 198, 8, p. 3089-3098 10 p.Research output: Contribution to journal › Article › peer-review
Open Access23 Scopus citations -
Hepatic amiodarone lipotoxicity is ameliorated by genetic and pharmacological inhibition of endoplasmatic reticulum stress
Erez, N., Hubel, E., Avraham, R., Cohen, R., Fishman, S., Bantel, H., Manns, M., Tirosh, B., Zvibel, I. & Shibolet, O., 1 Oct 2017, In: Toxicological Sciences. 159, 2, p. 402-412 11 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Predictors for advanced fibrosis in morbidly obese nonalcoholic fatty liver patients
Zelber-Sagi, S., Shoham, D., Zvibel, I., Abu-Abeid, S., Shibolet, O. & Fishman, S., 2017, In: World Journal of Hepatology. 9, 2, p. 91-98 8 p.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Sortilin Deficiency Reduces Ductular Reaction, Hepatocyte Apoptosis, and Liver Fibrosis in Cholestatic-Induced Liver Injury
Hubel, E., Saroha, A., Park, W. J., Pewzner-Jung, Y., Lavoie, E. G., Futerman, A. H., Bruck, R., Fishman, S., Dranoff, J. A., Shibolet, O. & Zvibel, I., 1 Jan 2017, In: American Journal of Pathology. 187, 1, p. 122-133 12 p.Research output: Contribution to journal › Article › peer-review
Open Access27 Scopus citations -
2015
Sortilin deficiency improves the metabolic phenotype and reduces hepatic steatosis of mice subjected to diet-induced obesity
Rabinowich, L., Fishman, S., Hubel, E., Thurm, T., Park, W. J., Pewzner-Jung, Y., Saroha, A., Erez, N., Halpern, Z., Futerman, A. H. & Zvibel, I., 1 Jan 2015, In: Journal of Hepatology. 62, 1, p. 175-181 7 p.Research output: Contribution to journal › Article › peer-review
55 Scopus citations -
2014
Discriminatory metabolic and inflammatory parameters in serum and omental adipose tissue of obese patients with different insulin sensitivity
Khatib, M., Zvibel, I., Zelber-Sagi, S., Varol, C., Lahat, G., Abu-Abeid, S., Klausner, J. M., Halpern, Z. & Fishman, S., Sep 2014, In: Journal of Clinical and Translational Endocrinology. 1, 3, p. 115-119 5 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Long-acting glucose-dependent insulinotropic polypeptide ameliorates obesity-induced adipose tissue inflammation
Varol, C., Zvibel, I., Spektor, L., Mantelmacher, F. D., Vugman, M., Thurm, T., Khatib, M., Elmaliah, E., Halpern, Z. & Fishman, S., 15 Oct 2014, In: Journal of Immunology. 193, 8, p. 4002-4009 8 p.Research output: Contribution to journal › Article › peer-review
Open Access60 Scopus citations -
2013
Dipeptidyl peptidase 4-deficient rats have improved bile secretory function in high fat diet-induced steatosis
Shlomo, S. B., Zvibel, I., Rabinowich, L., Goldiner, I., Shlomai, A., Santo, E. M., Halpern, Z., Oren, R. & Fishman, S., Jan 2013, In: Digestive Diseases and Sciences. 58, 1, p. 172-178 7 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
Role of glucose-dependent insulinotropic polypeptide in adipose tissue inflammation of dipeptidylpeptidase 4-deficient rats
Ben-Shlomo, S., Zvibel, I., Varol, C., Spektor, L., Shlomai, A., Santo, E. M., Halpern, Z., Oren, R. & Fishman, S., Nov 2013, In: Obesity. 21, 11, p. 2331-2341 11 p.Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
Transcriptional profiling identifies genes induced by hepatocyte-derived extracellular matrix in metastatic human colorectal cancer cell lines
Zvibel, I., Wagner, A., Pasmanik-Chor, M., Varol, C., Oron-Karni, V., Santo, E. M., Halpern, Z. & Kariv, R., Feb 2013, In: Clinical and Experimental Metastasis. 30, 2, p. 189-200 12 p.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
2012
Perinephric and epididymal fat affect hepatic metabolism in rats
Ben-Shlomo, S., Einstein, F. H., Zvibel, I., Atias, D., Shlomai, A., Halpern, Z., Barzilai, N. & Fishman, S., Jan 2012, In: Obesity. 20, 1, p. 151-156 6 p.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
The association between adipocytokines and biomarkers for nonalcoholic fatty liver disease-induced liver injury: A study in the general population
Zelber-Sagi, S., Ratziu, V., Zvibel, I., Goldiner, I., Blendis, L., Morali, G., Halpern, Z. & Oren, R., Mar 2012, In: European Journal of Gastroenterology and Hepatology. 24, 3, p. 262-269 8 p.Research output: Contribution to journal › Article › peer-review
31 Scopus citations -
2011
Glucagon-like peptide-1 reduces hepatic lipogenesis via activation of AMP-activated protein kinase
Ben-Shlomo, S., Zvibel, I., Shnell, M., Shlomai, A., Chepurko, E., Halpern, Z., Barzilai, N., Oren, R. & Fishman, S., Jun 2011, In: Journal of Hepatology. 54, 6, p. 1214-1223 10 p.Research output: Contribution to journal › Article › peer-review
249 Scopus citations -
2010
Thyroid hormones induce activation of rat hepatic stellate cells through increased expression of p75 neurotrophin receptor and direct activation of Rho
Zvibel, I., Atias, D., Phillips, A., Halpern, Z. & Oren, R., May 2010, In: Laboratory Investigation. 90, 5, p. 674-684 11 p.Research output: Contribution to journal › Article › peer-review
Open Access27 Scopus citations -
2009
Additive inhibitory effect of experimentally induced hepatic cirrhosis by agonists of peroxisome proliferator activator receptor γ and retinoic acid receptor
Bruck, R., Weiss, S., Aeed, H., Pines, M., Halpern, Z. & Zvibel, I., Feb 2009, In: Digestive Diseases and Sciences. 54, 2, p. 292-299 8 p.Research output: Contribution to journal › Article › peer-review
25 Scopus citations -
Syndecan 1 (CD138) serum levels: A novel biomarker in predicting liver fibrosis stage in patients with hepatitis C
Zvibel, I., Halfon, P., Fishman, S., Penaranda, G., Leshno, M., Or, A. B., Halpern, Z. & Oren, R., 2009, In: Liver International. 29, 2, p. 208-212 5 p.Research output: Contribution to journal › Article › peer-review
21 Scopus citations -
2008
Role of leisure-time physical activity in nonalcoholic fatty liver disease: A population-based study
Zelber-Sagi, S., Nitzan-Kaluski, D., Goldsmith, R., Webb, M., Zvibel, I., Goldiner, I., Blendis, L., Halpern, Z. & Oren, R., 2008, In: Hepatology. 48, 6, p. 1791-1798 8 p.Research output: Contribution to journal › Article › peer-review
Open Access203 Scopus citations -
The effect of Ras inhibition on the proliferation, apoptosis and matrix metalloproteases activity in rat hepatic stellate cells
Zvibel, I., Bar-Zohar, D., Kloog, Y., Oren, R. & Reif, S., Apr 2008, In: Digestive Diseases and Sciences. 53, 4, p. 1048-1053 6 p.Research output: Contribution to journal › Article › peer-review
16 Scopus citations -
2007
Induced hypothyroidism accelerates the regression of liver fibrosis in rats
Bruck, R., Weiss, S., Traister, A., Zvibel, I., Aeed, H., Halpern, Z. & Oren, R., Dec 2007, In: Journal of Gastroenterology and Hepatology (Australia). 22, 12, p. 2189-2194 6 p.Research output: Contribution to journal › Article › peer-review
34 Scopus citations -
2006
Isolation, characterization and culture of Thy1-positive cells from fetal rat livers
Isabel, Z., Miri, B., Einav, H., Ella, B. L., Zamir, H. & Ran, O., 28 Jun 2006, In: World Journal of Gastroenterology. 12, 24, p. 3841-3847 7 p.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
2005
Nicotinamide induces apoptosis and reduces collagen I and pro-inflammatory cytokines expression in rat hepatic stellate cells
Traister, A., Breitman, I., Bar-Lev, E., Zvibel, I., Harel, A., Halpern, Z. & Oren, R., Oct 2005, In: Scandinavian Journal of Gastroenterology. 40, 10, p. 1226-1234 9 p.Research output: Contribution to journal › Article › peer-review
37 Scopus citations -
Whole fetal liver transplantation - A new approach to cell therapy
Oren, R., Breitman, Y., Gur, E., Traister, A., Zvibel, I., Brazovsky, E., Shafritz, D. A. & Halpern, Z., Aug 2005, In: Liver Transplantation. 11, 8, p. 929-933 5 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
2004
Chimeric molecule IL-6/soluble IL-6 receptor is a potent mitogen for fetal hepatocytes
Zvibel, I., Brill, S., Kariv, R., Traister, A., Colan, T., Chebath, J., Halpern, Z., Revel, M. & Oren, R., Aug 2004, In: Journal of Cellular Physiology. 200, 2, p. 245-252 8 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
2003
A novel method for liver repopulation: Heterografting of micro-liver slices in a rat model
Gur, E., Deckel, R., Zvibel, I., Brazovsky, E., Kariv, R., Brill, S., Halpern, Z. & Oren, R., 1 Apr 2003, In: Liver Transplantation. 9, 4, p. 421-424 4 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Gliotoxin ameliorates development of fibrosis and cirrhosis in a thioacetamide rat model
Dekel, R., Zvibel, I., Brill, S., Brazovsky, E., Halpern, Z. & Oren, R., 1 Aug 2003, In: Digestive Diseases and Sciences. 48, 8, p. 1642-1647 6 p.Research output: Contribution to journal › Article › peer-review
52 Scopus citations -
Triiodothyronine and interleukin-6 (IL-6) induce expression of HGF in an immortalized rat hepatic stellate cell line
Kariv, R., Enden, A., Zvibel, I., Rosner, G., Brill, S., Shafritz, D. A., Halpern, Z. & Oren, R., 1 Jun 2003, In: Liver International. 23, 3, p. 187-193 7 p.Research output: Contribution to journal › Article › peer-review
26 Scopus citations -
2002
Heparin-derived disaccharides modulate proliferation and erb-B2-mediated signal transduction in colon cancer cell lines
Fishman, S., Brill, S., Papa, M., Halpern, Z. & Zvibel, I., 10 May 2002, In: International Journal of Cancer. 99, 2, p. 179-184 6 p.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Stromal extracellular matrix reduces chemotherapy-induced apoptosis in colon cancer cell lines
Kouniavsky, G., Khaikin, M., Zvibel, I., Zippel, D., Brill, S., Halpern, Z. & Papa, M., 2002, In: Clinical and Experimental Metastasis. 19, 1, p. 55-60 6 p.Research output: Contribution to journal › Article › peer-review
40 Scopus citations -
The role of fetal and adult hepatocyte extracellular matrix in the regulation of tissue-specific gene expression in fetal and adult hepatocytes
Brill, S., Zvibel, I., Halpern, Z. & Oren, R., 2002, In: European Journal of Cell Biology. 81, 1, p. 43-50 8 p.Research output: Contribution to journal › Article › peer-review
45 Scopus citations -
2001
Soluble and matrix-associated heparan sulfate proteoglycans increase expression of erb-b2 and erb-b3 in colon cancer cell lines
Zvibel, I., Brill, S., Halpern, Z., Moskovitz, S., Yayon, A. & Papa, M., 1 Feb 2001, In: International Journal of Cancer. 91, 3, p. 316-321 6 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Synergies of heparin and second messengers pathways involved in tissue-specific gene expression in hepatocytes
Zvibel, I., Moshe, P., Zamir, H. & Shlomo, B., 2001, In: Digestive Diseases and Sciences. 46, 5, p. 1039-1045 7 p.Research output: Contribution to journal › Article › peer-review
-
2000
Amphiregulin and hepatocyte-derived extracellular matrix regulate proliferation and autocrine growth factor expression in colon cancer cell lines of varying liver-colonizing capability
Zvibel, I., Brill, S., Halpern, Z. & Papa, M., 1 Feb 2000, In: Journal of Cellular Biochemistry. 76, 2, p. 332-340 9 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Hepatocyte-derived soluble factors regulate proliferation and autocrine growth factor expression in colon cancer cell lines of varying liver- colonizing capability
Zvibel, I., Brill, S., Papa, M. & Halpern, Z., 2000, In: Tumor Biology. 21, 4, p. 187-196 10 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
1999
Expansion conditions for early hepatic progenitor cells from embryonal and neonatal rat livers
Brill, S., Zvibel, I. & Reid, L. M., 1999, In: Digestive Diseases and Sciences. 44, 2, p. 364-371 8 p.Research output: Contribution to journal › Article › peer-review
26 Scopus citations -
1998
Extracellular matrix modulates expression of growth factors and growth- factor receptors in liver-colonizing colon-cancer cell lines
Zvibel, I., Halpern, Z. & Papa, M., 1998, In: International Journal of Cancer. 77, 2, p. 295-301 7 p.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
Hepatocyte extracellular matrix modulates expression of growth factors and growth factor receptors in human colon cancer cells
Zvibel, I., Brill, S., Halpern, Z. & Papa, M., 25 Nov 1998, In: Experimental Cell Research. 245, 1, p. 123-131 9 p.Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
Phenotypic characterization of rat hepatoma cell lines and lineage-specific regulation of gene expression by differentiation agents
Zvibel, I., Fiorino, A. S., Brill, S. & Reid, L. M., 1998, In: Differentiation. 63, 4, p. 215-223 9 p.Research output: Contribution to journal › Article › peer-review
Open Access23 Scopus citations -
1996
Disruption of cell-cell adhesion in the presence of sodium butyrate activates expression of the 92 kDa type IV collagenase in MDCK cells
Fiorino, A. S. & Zvibel, I., Jul 1996, In: Cell Biology International. 20, 7, p. 489-499 11 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
1995
Insulin‐like growth factor II regulation of gene expression in rat and human hepatomas
Zvibel, I., Brill, S. & Reid, L. M., Jan 1995, In: Journal of Cellular Physiology. 162, 1, p. 36-43 8 p.Research output: Contribution to journal › Article › peer-review
16 Scopus citations -
Maturation-dependent changes in the regulation of liver-specific gene expression in embryonal versus adult primary liver cultures
Brill, S., Zvibel, I. & Reid, L. M., 1995, In: Differentiation. 59, 2, p. 95-102 8 p.Research output: Contribution to journal › Article › peer-review
29 Scopus citations -
1994
Characterization and enrichment of fetal rat hepatoblasts by immunoadsorption (“panning”) and fluorescence‐activated cell sorting
Sigal, S. H., Brill, S., Reid, L. M., Zvibel, I., Gupta, S., Hixson, D., Faris, R. & Holst, P. A., Apr 1994, In: Hepatology. 19, 4, p. 999-1006 8 p.Research output: Contribution to journal › Article › peer-review
Open Access48 Scopus citations -
1993
Hepatic Progenitor Populations in Embryonic, Neonatal, and Adult Liver
Brill, S., Holst, P., Sigal, S., Zvibel, I., Fiorino, A., Ochs, A., Somasundaran, U. & Reid, L. M., Dec 1993, In: Experimental Biology and Medicine. 204, 3, p. 261-269 9 p.Research output: Contribution to journal › Article › peer-review
76 Scopus citations -
Suramin Inhibits Growth and Yet Promotes Insulin-like Growth Factor II Expression in HepG2 Cells
Kraft, A., Reid, L. M. & Zvibel, I., Feb 1993, In: Cancer Research. 53, 3, p. 652-657 6 p.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
1991
Heparin and Hormonal Regulation of mRNA Synthesis and Abundance of Autocrine Growth Factors: Relevance to Clonal Growth of Tumors
Zvibel, I., Halay, E. & Reid, L. M., Jan 1991, In: Molecular and Cellular Biology. 11, 1, p. 108-116 9 p.Research output: Contribution to journal › Article › peer-review
Open Access49 Scopus citations