gerry Cohen

2011

Implications of the inability of Listeria monocytogenes EGD-e to grow anaerobically due to a deletion in the class III NrdD ribonucleotide reductase for its use as a model laboratory strain

Ofer, A., Kreft, J., Logan, D. T., Cohen, G., Borovok, I. & Aharonowitz, Y., Jun 2011, In: Journal of Bacteriology. 193, 12, p. 2931-2940 10 p.

Research output: Contribution to journal › Article › peer-review

2010

Staphylococcus aureus NrdH redoxin is a reductant of the class Ib ribonucleotide reductase

Rabinovitch, I., Yanku, M., Yeheskel, A., Cohen, G., Borovok, I. & Aharonowitz, Y., Oct 2010, In: Journal of Bacteriology. 192, 19, p. 4963-4972 10 p.

Research output: Contribution to journal › Article › peer-review

2009

Diamide triggers mainly S thiolations in the cytoplasmic proteomes of Bacillus subtilis and Staphylococcus aureus

Pöther, D. C., Liebeke, M., Hochgräfe, F., Antelmann, H., Becher, D., Lalk, M., Lindequist, U., Borovok, I., Cohen, G., Aharonowitz, Y. & Hecker, M., Dec 2009, In: Journal of Bacteriology. 191, 24, p. 7520-7530 11 p.

Research output: Contribution to journal › Article › peer-review

Functional analysis of the Streptomyces coelicolor NrdR ATP-cone domain: Role in nucleotide binding, oligomerization, and DNA interactions

Grinberg, I., Shteinberg, T., Hassan, Q., Aharonowitz, Y., Borovok, I. & Cohen, G., Feb 2009, In: Journal of Bacteriology. 191, 4, p. 1169-1179 11 p.

Research output: Contribution to journal › Article › peer-review

Identification and characterization of gshA, a gene encoding the glutamate-cysteine ligase in the halophilic archaeon Haloferax volcanii

Malki, L., Yanku, M., Borovok, I., Cohen, G., Mevarech, M. & Aharonowitz, Y., Aug 2009, In: Journal of Bacteriology. 191, 16, p. 5196-5204 9 p.

Research output: Contribution to journal › Article › peer-review

2007

NrdR controls differential expression of the Escherichia coli ribonucleotide reductase genes

Torrents, E., Grinberg, I., Gorovitz-Harris, B., Lundström, H., Borovok, I., Aharonowitz, Y., Sjöberg, B. M. & Cohen, G., Jul 2007, In: Journal of Bacteriology. 189, 14, p. 5012-5021 10 p.

Research output: Contribution to journal › Article › peer-review

Staphylococcus aureus ArcR controls expression of the arginine deiminase operon

Makhlin, J., Kofman, T., Borovok, I., Kohler, C., Engelmann, S., Cohen, G. & Aharonowitz, Y., Aug 2007, In: Journal of Bacteriology. 189, 16, p. 5976-5986 11 p.

Research output: Contribution to journal › Article › peer-review

2006

Coenzyme B12 controls transcription of the Streptomyces class Ia ribonucleotide reductase nrdABS operon via a riboswitch mechanism

Borovok, I., Gorovitz, B., Schreiber, R., Aharonowitz, Y. & Cohen, G., Apr 2006, In: Journal of Bacteriology. 188, 7, p. 2512-2520 9 p.

Research output: Contribution to journal › Article › peer-review

The Streptomyces NrdR transcriptional regulator is a Zn ribbon/ATP cone protein that binds to the promoter regions of class Ia and class II ribonucleotide reductase operons

Grinberg, I., Shteinberg, T., Gorovitz, B., Aharonowitz, Y., Cohen, G. & Borovok, I., Nov 2006, In: Journal of Bacteriology. 188, 21, p. 7635-7644 10 p.

Research output: Contribution to journal › Article › peer-review

2005

A multidomain fusion protein in Listeria monocytogenes catalyzes the two primary activities for glutathione biosynthesis

Gopal, S., Borovok, I., Ofer, A., Yanku, M., Cohen, G., Goebel, W., Kreft, J. & Aharonowitz, Y., Jun 2005, In: Journal of Bacteriology. 187, 11, p. 3839-3847 9 p.

Research output: Contribution to journal › Article › peer-review

Single chain antibody against the common epitope of mutant p53 restores wild-type activity to mutant p53 protein

Orgad, S., Goldfinger, N., Cohen, G., Rotter, V. & Solomon, B., 24 Oct 2005, In: FEBS Letters. 579, 25, p. 5609-5615 7 p.

Research output: Contribution to journal › Article › peer-review

2004

Alternative oxygen-dependent and oxygen-independent ribonucleotide reductases in Streptomyces: Cross-regulation and physiological role in response to oxygen limitation

Borovok, I., Gorovitz, B., Yanku, M., Schreiber, R., Gust, B., Chater, K., Aharonowitz, Y. & Cohen, G., Nov 2004, In: Molecular Microbiology. 54, 4, p. 1022-1035 14 p.

Research output: Contribution to journal › Article › peer-review

Role of a Cysteine Synthase in Staphylococcus aureus

Lithgow, J. K., Hayhurst, E. J., Cohen, G., Aharonowitz, Y. & Foster, S. J., Mar 2004, In: Journal of Bacteriology. 186, 6, p. 1579-1590 12 p.

Research output: Contribution to journal › Article › peer-review

Transcriptional Regulation of the Staphylococcus aureus Thioredoxin and Thioredoxin Reductase Genes in Response to Oxygen and Disulfide Stress

Uziel, O., Borovok, I., Schreiber, R., Cohen, G. & Aharonowitz, Y., Jan 2004, In: Journal of Bacteriology. 186, 2, p. 326-334 9 p.

Research output: Contribution to journal › Article › peer-review

2002

Streptomyces spp. contain class Ia and class II ribonucleotide reductases: Expression analysis of the genes in vegetative growth

Borovok, I., Kreisberg-Zakarin, R., Yanko, M., Schreiber, R., Myslovati, M., Åslund, F., Holmgren, A., Cohen, G. & Aharonowitz, Y., 2002, In: Microbiology. 148, 2, p. 391-404 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2001

Analysis of transcription of the Staphylococcus aureus aerobic class Ib and anaerobic class III ribonucleotide reductase genes in response to oxygen

Masalha, M., Borovok, I., Schreiber, R., Aharonowitz, Y. & Cohen, G., 2001, In: Journal of Bacteriology. 183, 24, p. 7260-7272 13 p.

Research output: Contribution to journal › Article › peer-review

Bacterial thiol-disulfide redox metabolism: A new target for rational drug design

Cohen, G., Borovok, I., Uziel, O., Schreiber, R. & Aharonowitz, Y., 2001, In: Periodicum Biologorum. 103, 2, p. 153-155 3 p.

Research output: Contribution to journal › Article › peer-review

Defining the disulphide stress response in Streptomyces coelicolor A3(2): Identification of the σ^R regulon

Paget, M. S. B., Molle, V., Cohen, G., Aharonowitz, Y. & Buttner, M. J., 2001, In: Molecular Microbiology. 42, 4, p. 1007-1020 14 p.

Research output: Contribution to journal › Article › peer-review

Single-chain antibody against the common epitope of mutant p53: Isolation and intracytosolic expression in mammalian cells

Govorko, D., Cohen, G. & Solomon, B., 1 Dec 2001, In: Journal of Immunological Methods. 258, 1-2, p. 169-181 13 p.

Research output: Contribution to journal › Article › peer-review

2000

Structure-function studies of the non-heme iron active site of isopenicillin N synthase: Some implications for catalysis

Kreisberg-Zakarin, R., Borovok, I., Yanko, M., Frolow, F., Aharonowitz, Y. & Cohen, G., 30 Aug 2000, In: Biophysical Chemistry. 86, 2-3, p. 109-118 10 p.

Research output: Contribution to journal › Article › peer-review

1999

Recent advances in the structure and function of isopenicillin N synthase

Kreisberg-Zakarin, R., Borovok, I., Yanko, M., Aharonowitz, Y. & Cohen, G., 1999, In: Antonie van Leeuwenhoek. 75, 1-2, p. 33-39 7 p.

Research output: Contribution to journal › Review article › peer-review

1998

Gene organization in the trxA/B-oriC region of the Streptomyces coelicolor chromosome and comparison with other eubacteria

Gal-Mor, O., Borovok, I., Av-Gay, Y., Cohen, G. & Aharonowitz, Y., 14 Sep 1998, In: Gene. 217, 1-2, p. 83-90 8 p.

Research output: Contribution to journal › Article › peer-review

1997

Biological significance of the genetic linkage between streptolysin s expression and riboflavin biosynthesis in Streptococcus pyogenes

Gargir, A., Liu, S., Sela, S., Cohen, G., Jadoun, J., Cheung, A. & Ofek, I., 1997, In: Advances in Experimental Medicine and Biology. 418, p. 987-989 3 p.

Research output: Contribution to journal › Article › peer-review

Insertional inactivation of streptolysin S expression is associated with altered riboflavin metabolism in Streptococcus pyogenes

Liu, S., Sela, S., Cohen, G., Jadoun, J., Cheung, A. & Ofek, I., Apr 1997, In: Microbial Pathogenesis. 22, 4, p. 227-234 8 p.

Research output: Contribution to journal › Article › peer-review

The glutamine ligand in the ferrous iron active site of isopenicillin N synthase of Streptomyces jumonjinensis is not essential for catalysis

Landman, O., Borovok, I., Aharonowitz, Y. & Cohen, G., 24 Mar 1997, In: FEBS Letters. 405, 2, p. 172-174 3 p.

Research output: Contribution to journal › Article › peer-review

1996

Distribution of thiols in microorganisms: Mycothiol is a major thiol in most actinomycetes

Newton, G. L., Arnold, K., Price, M. S., Sherrill, C., Delcardayre, S. B., Aharonowitz, Y., Cohen, G., Davies, J., Fahey, R. C. & Davis, C., Apr 1996, In: Journal of Bacteriology. 178, 7, p. 1990-1995 6 p.

Research output: Contribution to journal › Article › peer-review

Ferrous active site of isopenicillin N synthase: Genetic and sequence analysis of the endogenous ligands

Borovok, I., Landman, O., Kreisberg-Zakarin, R., Aharonowitz, Y. & Cohen, G., 13 Feb 1996, In: Biochemistry. 35, 6, p. 1981-1987 7 p.

Research output: Contribution to journal › Article › peer-review

The bacteriophage P1 lytic replicon: Directionality of replication and cis-acting elements

Cohen, G., Or, E., Minas, W. & Sternberg, N. L., 10 Oct 1996, In: Gene. 175, 1-2, p. 151-155 5 p.

Research output: Contribution to journal › Article › peer-review

1995

Dethiobiotin Synthetase: The Carbonylation of 7,8-Diaminononanoic Acid Proceeds Regiospecifically via the N7-Carbamate

Gibson, K. J., Lorimer, G. H., Rendina, A. R., Taylor, W. S., Cohen, G., Gatenby, A. A., Payne, W. G., Roe, D. C., Lockett, B. A., Nudelman, A., Marcovici, D., Nachum, A., Wexler, B. A., Marsilii, E. L., Turner, I. M., Howe, L. D., Kalbach, C. E. & Chi, H., Sep 1995, In: Biochemistry. 34, 35, p. 10976-10984 9 p.

Research output: Contribution to journal › Article › peer-review

Erratum: Dethiobiotin synthetase: The carbonylation of 7,8- diaminononanoic acid proceeds regiospecifically via the N7-carbamate (Biochemistry (September 5, 1995) 34:35 (10976-10984))

Gibson, K. J., Lorimer, G. H., Rendina, A. R., Taylor, W. S., Cohen, G., Gatenby, A. A., Payne, W. G., Roe, D. C., Lockett, B. A., Nudelman, A., Marcovici, D., Nachum, A., Wexler, B. A., Marsilii, E. L., Turner, I. M., Howe, L. D., Kalbach, C. E. & Chi, H., 1995, In: Biochemistry. 34, 48, p. 15880 1 p.

Research output: Contribution to journal › Comment/debate

The Structure of U17 Isolated from Streptomyces clavuligerus and its Properties as an Antioxidant Thiol

Newton, G. L., Bewley, C. A., Dwyer, T. J., Horn, R., Aharonowitz, Y., Cohen, G., Davies, J., Faulkner, D. J. & Fahey, R. C., Jun 1995, In: European Journal of Biochemistry. 230, 2, p. 821-825 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1994

Biotin Synthase: Purification, Characterization as a [2Fe-2S] Cluster Protein, and in Vitro Activity of the Escherichia coli bioB Gene Product

Sanyal, I., Flint, D. H. & Cohen, G., 1 Mar 1994, In: Biochemistry. 33, 12, p. 3625-3631 7 p.

Research output: Contribution to journal › Article › peer-review

The thioredoxin system of Penicillium chrysogenum and its possible role in penicillin biosynthesis

Cohen, G., Argaman, A., Schreiber, R., Mislovati, M. & Aharonowitz, Y., 1994, In: Journal of Bacteriology. 176, 4, p. 973-984 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1993

Characterization of a broad-range disulfide reductase from Streptomyces clavuligerus and its possible role in β-lactam antibiotic biosynthesis

Aharonowitz, Y., Av-Gay, Y., Schreiber, R. & Cohen, G., 1993, In: Journal of Bacteriology. 175, 3, p. 623-629 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Low-molecular-weight thiols in streptomycetes and their potential role as antioxidants

Newton, G. L., Fahey, R. C., Cohen, G. & Aharonowitz, Y., 1993, In: Journal of Bacteriology. 175, 9, p. 2734-2742 9 p.

Research output: Contribution to journal › Article › peer-review

Review

Aharonowitz, Y., Bergmeyer, J., Cantoral, J. M., Cohen, G., Demain, A. L., Fink, U., Kinghorn, J., Kleinkauf, H., MacCabe, A., Palissa, H., Pfeifer, E., Schwecke, T., van Liempt, H., von Döhren, H., Wolfe, S. & Zhang, J., Jul 1993, In: Bio/Technology. 11, 7, p. 807-810 4 p.

Research output: Contribution to journal › Article › peer-review

Thioredoxin-thioredoxin reductase system of Streptomyces clavuligerus: Sequences, expression, and organization of the genes

Cohen, G., Yanko, M., Mislovati, M., Argaman, A., Schreiber, R., Av-Gay, Y. & Aharonowitz, Y., 1993, In: Journal of Bacteriology. 175, 16, p. 5159-5167 9 p.

Research output: Contribution to journal › Article › peer-review

1992

Penicillin and cephalosporin biosynthetic genes: Structure, organization, regulation, and evolution

Aharonowitz, Y., Cohen, G. & Martin, J. F., 1992, In: Annual Review of Microbiology. 46, p. 461-495 35 p.

Research output: Contribution to journal › Review article › peer-review

Streptomyces contain a 7.0 KDa cold shock like protein

Av-gay, Y., Aharonowitz, Y. & Cohen, G., 25 Oct 1992, In: Nucleic Acids Research. 20, 20, p. 5478 1 p.

Research output: Contribution to journal › Article › peer-review

1991

High level expression in Escherichia coli of isopenicillin N synthase genes from Flavobacterium and Streptomyces, and recovery of active enzyme from inclusion bodies

Landman, O., Shiffman, D., Av-Gay, Y., Aharonowitz, Y. & Cohen, G., 1 Dec 1991, In: FEMS Microbiology Letters. 84, 3, p. 239-244 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1990

1989

Genetic analysis of the lytic replicon of bacteriophage P1. I. Isolation and partial characterization

Cohen, G. & Sternberg, N., 5 May 1989, In: Journal of Molecular Biology. 207, 1, p. 99-109 11 p.

Research output: Contribution to journal › Article › peer-review

Genetic analysis of the lytic replicon of bacteriophage P1. II. organization of replicon elements

Sternberg, N. & Cohen, G., 5 May 1989, In: Journal of Molecular Biology. 207, 1, p. 111-133 23 p.

Research output: Contribution to journal › Article › peer-review

1988

Cloning and comparative sequence analysis of the gene coding for isopenicillin N synthase in Streptomyces

Shiffman, D., Mevarech, M., Jensen, S. E., Cohen, G. & Aharonowitz, Y., Nov 1988, In: Molecular Genetics and Genomics. 214, 3, p. 562-569 8 p.

Research output: Contribution to journal › Article › peer-review

Isolation and characterization of a linear DNA plasmid from Streptomyces clavuligerus

Keen, C. L., Mendelovitz, S., Cohen, G., Aharonowitz, Y. & Roy, K. L., Apr 1988, In: Molecular Genetics and Genomics. 212, 1, p. 172-176 5 p.

Research output: Contribution to journal › Article › peer-review

1987

Construction of an ordered overlapping library of bacteriophage P1 DNA in phage vector λD69

O'Regan, G. T., Sternberg, N. L. & Cohen, G., 1987, In: Gene. 60, 1, p. 129-135 7 p.

Research output: Contribution to journal › Article › peer-review

1986

[13] Solid-Phase Assay for d-Biotin and Avidin on Cellulose Disks

Goldstein, L., Yankofsky, S. A. & Cohen, G., 1 Jan 1986, In: Methods in Enzymology. 122, C, p. 72-82 11 p.

Research output: Contribution to journal › Article › peer-review

1983

Electron microscopy study of early lytic replication forms of bacteriophage P1 DNA

Cohen, G., Nov 1983, In: Virology. 131, 1, p. 159-170 12 p.

Research output: Contribution to journal › Article › peer-review

gerry Cohen

Research output

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