Gad Lavie

2014

Tellurium compound AS101 ameliorates experimental autoimmune encephalomyelitis by vla-4 inhibition and suppression of monocyte and T cell infiltration into the CNS

Lee, J. H., Halperin-Sheinfeld, M., Baatar, D., Mughal, M. R., Tae, H. J., Kim, J. W., Carter, A., Lustig, A., Snir, O., Lavie, G., Okun, E., Mattson, M. P., Sredni, B. & Taub, D. D., Jun 2014, In: NeuroMolecular Medicine. 16, 2, p. 292-307 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

14 Scopus citations

2013

Unique Anti-Glioblastoma Activities of Hypericin Are at the Crossroad of Biochemical and Epigenetic Events and Culminate in Tumor Cell Differentiation

Dror, N., Mandel, M. & Lavie, G., 16 Sep 2013, In: PLoS ONE. 8, 9, e73625.

Research output: Contribution to journal › Article › peer-review

Open Access

20 Scopus citations

2011

Degradation of HIF-1alpha under hypoxia combined with induction of Hsp90 polyubiquitination in cancer cells by hypericin: A unique cancer therapy

Barliya, T., Mandel, M., Livnat, T., Weinberger, D. & Lavie, G., 19 Sep 2011, In: PLoS ONE. 6, 9, e22849.

Research output: Contribution to journal › Article › peer-review

Open Access

46 Scopus citations

2009

Clone clusters in autoreactive CD4 T-cell lines from probable multiple sclerosis patients form disease-characteristic signatures

Mandel, M., Achiron, A., Tuller, T., Barliya, T., Rechavi, G., Amariglio, N., Loewenthal, R. & Lavie, G., Oct 2009, In: Immunology. 128, 2, p. 287-300 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

2008

Δ9-Tetrahydrocannabinol inhibits cell cycle progression by downregulation of E2F1 in human glioblastoma multiforme cells

Galanti, G., Fisher, T., Kventsel, I., Shoham, J., Gallily, R., Mechoulam, R., Lavie, G., Amariglio, N., Rechavi, G. & Toren, A., 2008, In: Acta Oncologica. 47, 6, p. 1062-1070 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

47 Scopus citations

2007

"Competitive quenching": A mechanism by which perihydroxylated perylenequinone photosensitizers can prevent adverse phototoxic damage caused by verteporfin during photodynamic therapy

Lavie, G., Barliya, T., Mandel, M., Blank, M., Ron, Y., Orenstein, A., Livnat, T., Friedman, N., Weiner, L., Sheves, M. & Weinberger, D., Sep 2007, In: Photochemistry and Photobiology. 83, 5, p. 1270-1277 8 p.

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Mechanisms operative in the antitumor activity of temozolomide in glioblastoma multiforme

Fisher, T., Galanti, G., Lavie, G., Jacob-Hirsch, J., Kventsel, I., Zeligson, S., Winkler, R., Simon, A. J., Amariglio, N., Rechavi, G. & Toren, A., Sep 2007, In: Cancer journal (Sudbury, Mass.). 13, 5, p. 335-344 10 p.

Research output: Contribution to journal › Article › peer-review

32 Scopus citations

2006

Effective prevention of microbial biofilm formation on medical devices by low-energy surface acoustic waves

Kazan, Z., Zumeris, J., Jacob, H., Raskin, H., Kratysh, G., Vishnia, M., Dror, N., Barliya, T., Mandel, M. & Lavie, G., Dec 2006, In: Antimicrobial Agents and Chemotherapy. 50, 12, p. 4144-4152 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

109 Scopus citations

G-CSF enhances the adhesion of encephalitogenic T cells to extracellular matrix components: A possible mechanism for exacerbation of multiple sclerosis

Snir, O., Lavie, G., Achiron, A., Bank, I., Ben-Aharon, T., Sredni, B., Cohen, I. R. & Mandel, M., Mar 2006, In: Journal of Neuroimmunology. 172, 1-2, p. 145-155 11 p.

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

2005

Anti-angiogenic activities of hypericin in vivo: Potential for ophthalmologic applications

Lavie, G., Mandel, M., Hazan, S., Barliya, T., Blank, M., Grunbaum, A., Meruelo, D. & Solomon, A., Mar 2005, In: Angiogenesis. 8, 1, p. 35-42 8 p.

Research output: Contribution to journal › Article › peer-review

32 Scopus citations

Anti-proliferative activity of haloperidol in B16 mouse and human SK-MEL-28 melanoma cell lines

Nordenberg, J., Perlmutter, I., Lavie, G., Beery, E., Uziel, O., Morgenstern, C., Fenig, E. & Weizman, A., Oct 2005, In: International Journal of Oncology. 27, 4, p. 1097-1103 7 p.

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Competitive quenching: A possible novel approach in protecting RPE cells from damage during PDT

Weinberger, D., Ron, Y., Lusky, M., Gaaton, D., Orenstein, A., Blank, M., Mandel, M., Livnat, T., Barliya, T. & Lavie, G., Apr 2005, In: Current Eye Research. 30, 4, p. 269-277 9 p.

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Unique gene expression patterns in human T-cell lines generated from multiple sclerosis patients by stimulation with a synthetic MOG peptide

Mandel, M., Gurevich, M., Lavie, G., Cohen, I. R. & Achiron, A., Sep 2005, In: Clinical and Developmental Immunology. 12, 3, p. 203-209 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

2004

Antimetastatic activity of the photodynamic agent hypericin in the dark

Blank, M., Lavie, G., Mandel, M., Hazan, S., Urenstein, A., Meruelo, D. & Keisari, Y., 10 Sep 2004, In: International Journal of Cancer. 111, 4, p. 596-603 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

53 Scopus citations

T cell vaccination in multiple sclerosis relapsing-remitting nonresponders patients

Achiron, A., Lavie, G., Kishner, I., Stern, Y., Sarova-Pinhas, I., Ben-Aharon, T., Barak, Y., Raz, H., Lavie, M., Barliya, T., Faibel, M., Cohen, I. R. & Mandel, M., Nov 2004, In: Clinical Immunology. 113, 2, p. 155-160 6 p.

Research output: Contribution to journal › Article › peer-review

46 Scopus citations

2003

Enhanced Ubiquitinylation of Heat Shock Protein 90 as a Potential Mechanism for Mitotic Cell Death in Cancer Cells Induced with Hypericin

Blank, M., Mandel, M., Keisari, Y., Meruelo, D. & Lavie, G., 1 Dec 2003, In: Cancer Research. 63, 23, p. 8241-8247 7 p.

Research output: Contribution to journal › Article › peer-review

81 Scopus citations

2002

Interaction of disease-related antigen-reactive T-cell lines from multiple sclerosis patients with type IV collagen: Role of integrin VLA-1 and effects of irradiation

Bank, I., Achiron, A., Lavie, G., Koltakov, A. & Mandel, M., 2002, In: Journal of Clinical Immunology. 22, 3, p. 153-163 11 p.

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Wavelength-dependent properties of photodynamic therapy using hypericin in vitro and in an animal model

Blank, M., Kostenich, G., Lavie, G., Kimel, S., Keisari, Y. & Orenstein, A., 1 Sep 2002, In: Photochemistry and Photobiology. 76, 3, p. 335-340 6 p.

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

2001

ANTI-cancer activities of hypericin in the dark

Blank, M., Mandel, M., Hazan, S., Keisari, Y. & Lavie, G., 1 Aug 2001, In: Photochemistry and Photobiology. 74, 2, p. 120-125 6 p.

Research output: Contribution to journal › Article › peer-review

45 Scopus citations

2000

Effects of photodynamic therapy with hypericin in mice bearing highly invasive solid tumors

Blank, M., Lavie, G., Mandel, M. & Keisari, Y., 2000, In: Oncology Research. 12, 9-10, p. 409-418 10 p.

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Inhibition of the CD8⁺ T cell-mediated cytotoxicity reaction by hypericin: Potential for treatment of T cell-mediated diseases

Lavie, G., Meruelo, D., Aroyo, K. & Mandel, M., 2000, In: International Immunology. 12, 4, p. 479-486 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

18 Scopus citations

Strategies for evaluation of enveloped virus inactivation in red cell concentrates using hypericin

Prince, A. M., Pascual, D., Meruelo, D., Liebes, L., Mazur, Y., Dubovi, E., Mandel, M. & Lavie, G., 1 Feb 2000, In: Photochemistry and Photobiology. 71, 2, p. 188-195 8 p.

Research output: Contribution to journal › Article › peer-review

59 Scopus citations

1999

A photodynamic pathway to apoptosis and necrosis induced by dimethyl tetrahydroxyhelianthrone and hypericin in leukaemic cells: Possible relevance to photodynamic therapy

Lavie, G., Kaplinsky, C., Toren, A., Aizman, I., Meruelo, D., Mazur, Y. & Mandel, M., 1999, In: British Journal of Cancer. 79, 3-4, p. 423-432 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

89 Scopus citations

1995

The chemical and biological properties of hypericina compound with a broad spectrum of biological activities

Lavie, G., Mazur, Y., Lavie, D. & Meruelo, D., Mar 1995, In: Medicinal Research Reviews. 15, 2, p. 111-119 9 p.

Research output: Contribution to journal › Article › peer-review

182 Scopus citations

1994

Acidic properties of hypericin and its octahydroxy analogue in the ground and excited states

Freeman, D., Frolow, F., Kapinus, E., Lavie, D., Lavie, G., Meruelo, D. & Mazur, Y., 1994, In: Chemical Communications. 7, p. 891-892 2 p.

Research output: Contribution to journal › Article › peer-review

82 Scopus citations

1993

Photodynamic inactivation of radiation leukemia virus produced from hypericin-treated cells

Degar, S., Lavie, G. & Meruelo, D., Dec 1993, In: Virology. 197, 2, p. 796-800 5 p., 71660.

Research output: Contribution to journal › Article › peer-review

Open Access

16 Scopus citations

1992

Inactivation of the Human Immunodeficiency Virus by Hypericin: Evidence for Photochemical Alterations of p24 and a Block in Uncoating

Degar, S., Prince, A. M., Pascual, D., Lavie, G., Levin, B., Mazur, Y., Lavie, D., Ehrlich, L. S., Carter, C. & Meruelo, D., Nov 1992, In: AIDS Research and Human Retroviruses. 8, 11, p. 1929-1936 8 p.

Research output: Contribution to journal › Article › peer-review

78 Scopus citations

1991

A method for the quantitation of hypericin, an antiviral agent, in biological fluids by high-performance liquid chromatography

Liebes, L., Mazur, Y., Freeman, D., Lavie, D., Lavie, G., Kudler, N., Mendoza, S., Levin, B., Hochster, H. & Meruelo, D., 15 May 1991, In: Analytical Biochemistry. 195, 1, p. 77-85 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

72 Scopus citations

1990

Hypericin as an Antiretroviral Agent: Mode of Action and Related Analogues

LAVIE, G., MAZUR, Y., LAVIE, D., LEVIN, B., ITTAH, Y. & MERUELO, D., Dec 1990, In: Annals of the New York Academy of Sciences. 616, 1, p. 556-562 7 p.

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

1989

Cell surface-associated proteinases in NK cell-mediated cytotoxicity: Enhancement of enzyme expression is unique to activation with interferon-α

Lavie, G. & Zucker-Franklin, D., Dec 1989, In: Cellular Immunology. 124, 2, p. 202-211 10 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Studies of the mechanisms of action of the antiretroviral agents hypericin and pseudohypericin

Lavie, G., Valentine, F., Levin, B., Mazur, Y., Gallo, G., Lavie, D., Weiner, D. & Meruelo, D., 1989, In: Proceedings of the National Academy of Sciences of the United States of America. 86, 15, p. 5963-5967 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

242 Scopus citations

1988

Therapeutic agents with dramatic antiretroviral activity and little toxicity at effective doses: Aromatic polycyclic diones hypericin and pseudohypericin

Meruelo, D., Lavie, G. & Lavie, D., 1988, In: Proceedings of the National Academy of Sciences of the United States of America. 85, 14, p. 5230-5234 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

450 Scopus citations

1987

Experience with bacillus Calmette-Guerin in patients with superficial bladder tumors. Value of monocyte activation in intravesical bacillus Calmette-Guerin therapy

Nissenkorn, I., Lavie, G., Keisari, Y., Leib, Z., Vilcovsky, E., Servadio, C. & Shachter, H., 1987, In: European Urology. 13, 4, p. 246-250 5 p.

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Human monoclonal antibodies derived from lymph nodes of a patient with breast carcinoma react with MuMTV polypeptides

Shoenfeld, Y., Hizi, A., Tal, R., Smorodinsky, N. I., Lavie, G., Mor, C., Schteren, S., Mammon, Z., Pinkhas, J. & Keydar, T., 1 Jan 1987, In: Cancer. 59, 1, p. 43-50 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

16 Scopus citations

Two Israeli patients with homozygous familial hypercholesterolemia treated by long-term plasma exchange

Lurie, Y., Lavie, G., Wysenbeek, A. J., Beigel, Y., Green, P., Schoenfeld, N. & Atsmon, A., 1987, In: Plasma Therapy and Transfusion Technology. 8, 3, p. 239-245 7 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

1986

Monoclonal anti-tuberculosis antibodies react with DNA, and monoclonal anti-DNA autoantibodies react with Mycobacterium tuberculosis

Shoenfeld, Y., Vilner, Y., Coates, A. R. M., Rauch, J., Lavie, G., Shaul, D. & Pinkhas, J., 1986, In: Clinical and Experimental Immunology. 66, 2, p. 255-261 7 p.

Research output: Contribution to journal › Article › peer-review

105 Scopus citations

The detection of a common idiotype of anti-DNA antibodies in the sera of patients with monoclonal gammopathies

Shoenfeld, Y., Ben-Yehuda, O., Napartstek, Y., Wilner, Y., Frolichman, R., Schattner, A., Lavie, G., Joshua, H., Pinkhas, J., Kennedy, R. C., Schwartz, R. S. & Pick, A. I., May 1986, In: Journal of Clinical Immunology. 6, 3, p. 194-204 11 p.

Research output: Contribution to journal › Article › peer-review

61 Scopus citations

The leukergy test in patients with ischemic heart disease

Berliner, S., Sclarovsky, S., Lavie, G., Pinkhas, J., Aronson, M. & Agmon, J., Jan 1986, In: American Heart Journal. 111, 1, p. 19-22 4 p.

Research output: Contribution to journal › Article › peer-review

44 Scopus citations

1985

Amphotericin B causes aggregation of neutrophils and enhances pulmonary leukostasis

Berliner, S., Weinberger, M., Ben-Bassat, M., Lavie, G., Giller, S. & Pinkhas, J., 1985, In: American Review of Respiratory Disease. 132, 3, p. 602-605 4 p.

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Human lupus monoclonal autoantibodies bind to Raji cells

Shoenfeld, Y., Smorodinsky, N. I., Lavie, G., Hazaz, B., Joshua, H. & Pinkhas, J., 1985, In: Immunology Letters. 11, 2, p. 121-126 6 p.

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Human monoclonal anti‐DNA antibodies react as lymphocytotoxic antibodies

Shoenfeld, Y., Zamir, R., Joshua, H., Lavie, G. & Pinkhas, J., 1985, In: European Journal of Immunology. 15, 10, p. 1024-1028 5 p.

Research output: Contribution to journal › Article › peer-review

54 Scopus citations

Stimulation of human monocyte oxidative burst and related cytotoxicity by tumor‐promoting and non‐tumorpromoting diterpene esters, indole alkaloids and polyacetate‐type agents

Keisari, Y., Geva, I., Flescher, E., Goldin, H. & Lavie, G., 15 Oct 1985, In: International Journal of Cancer. 36, 4, p. 467-472 6 p.

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

The leukergy test in rheumatic diseases. New implications for an old test

Berliner, S., Abramovitz, M., Kariv, N., Weinberger, A., Yaron, M., Lavie, G., Pinkhas, J. & Aronson, M., Aug 1985, In: Arthritis and Rheumatology. 28, 8, p. 899-903 5 p.

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

The mechanism of human NK cell-mediated cytotoxicity. Mode of action of surface-associated proteases in the early stages of the lytic reaction

Lavie, G., Leib, Z. & Servadio, C., 1985, In: Journal of Immunology. 135, 2, p. 1470-1476 7 p.

Research output: Contribution to journal › Article › peer-review

44 Scopus citations

1984

A “new” phenotype confirming a relationship between Cr^a and Tc^a

LEVENE, C., HAKEI, N., LAVIE, G., GKEENBEKG, S., LAIRD‐FRYER, B. & DANIELS, G. L., 1984, In: Transfusion. 24, 1, p. 13-15 3 p.

Research output: Contribution to journal › Article › peer-review

33 Scopus citations

1982

Homogeneous populations of macrophages from histiocytic lymphoma patients as a source for macrophage subpopulations which differ in immunoregulatory properties

Lavie, G., Shoenfeld, Y., Shaklai, M., Aderka, D., Pick, A. I. & Pinkhas, J., 1 Jul 1982, In: Cancer. 50, 1, p. 69-77 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

1981

Clinical and immunochemical studies of 20 patients with amyloidosis and plasma cell dyscrasia

Pick, A. I., Frohlichmann, R., Lavie, G., Duczyminer, M. & Skvaril, F., 1981, In: Unknown Journal. 66, 3, p. 154-167 14 p.

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Demonstration of membrane-bound proteolytic activity on the surface of mononuclear leukocytes

Zucker-Franklin, D., Lavie, G. & Franklin, E. C., 1981, In: Journal of Histochemistry and Cytochemistry. 29, 3 a Suppl., p. 451-456 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

27 Scopus citations

1980

Current concepts of the structure and pathogenesis of the amyloid diseases

Franklin, E. C., Lavie, G. & Zucker-Franklin, D., Jan 1980, In: Ricerca in Clinica e in Laboratorio. 10, 1, p. 3-7 5 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Elastase-type proteases on the surface of human blood monocytes: Possible role in amyloid formation

Lavie, G., Zucker-Franklin, D. & Franklin, E. C., 1980, In: Journal of Immunology. 125, 1, p. 175-180 6 p.

Research output: Contribution to journal › Article › peer-review

99 Scopus citations

Gad Lavie

Research output

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