Research output per year
Research output per year
- 1 - 50 out of 52 results
Search results
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2012
Molecular alterations associated with the NMDA preconditioning-induced neuroprotective mechanism against glutamate cytotoxicity
Sragovich, S., Bromberg, Y., Sperling, O. & Zoref-Shani, E., Jul 2012, In: Journal of Molecular Neuroscience. 47, 3, p. 519-532 14 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Neuroprotection by NMDA preconditioning against glutamate cytotoxicity is mediated through activation of ERK 1/2, inactivation of JNK, and by prevention of glutamate-induced CREB inactivation
Navon, H., Bromberg, Y., Sperling, O. & Shani, E., Feb 2012, In: Journal of Molecular Neuroscience. 46, 1, p. 100-108 9 p.Research output: Contribution to journal › Article › peer-review
23 Scopus citations -
2009
Involvement of Src tyrosine kinases (SFKs) and of focal adhesion kinase (FAK) in the injurious mechanism in rat primary neuronal cultures exposed to chemical ischemia
Shani, V., Bromberg, Y., Sperling, O. & Zoref-Shani, E., Jan 2009, In: Journal of Molecular Neuroscience. 37, 1, p. 50-59 10 p.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
2007
Identification and characterization of the first mutation (Arg776Cys) in the C-terminal domain of the Human Molybdenum Cofactor Sulfurase (HMCS) associated with type II classical xanthinuria
Peretz, H., Naamati, M. S., Levartovsky, D., Lagziel, A., Shani, E., Horn, I., Shalev, H. & Landau, D., May 2007, In: Molecular Genetics and Metabolism. 91, 1, p. 23-29 7 p.Research output: Contribution to journal › Article › peer-review
50 Scopus citations -
2006
Molecular, biochemical, and genetic characterization of a female patient with Lesch-Nyhan disease
Rinat, C., Zoref-Shani, E., Ben-Neriah, Z., Bromberg, Y., Becker-Cohen, R., Feinstein, S., Sperling, O. & Frishberg, Y., Mar 2006, In: Molecular Genetics and Metabolism. 87, 3 SPEC. ISS., p. 249-252 4 p.Research output: Contribution to journal › Article › peer-review
22 Scopus citations -
The neuroprotective adenosine-activated signal transduction pathway involves activation of phospholipase C
Rogel, A., Bromberg, Y., Sperling, O. & Zoref-Shani, E., 1 Jun 2006, In: Nucleosides, Nucleotides and Nucleic Acids. 25, 9-11, p. 1283-1286 4 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
2005
Oxidative stress activates transcription factor Nf-κB-mediated protective signaling in primary rat neuronal cultures
Kratsovnik, E., Bromberg, Y., Sperling, O. & Zoref-Shani, E., May 2005, In: Journal of Molecular Neuroscience. 26, 1, p. 27-32 6 p.Research output: Contribution to journal › Article › peer-review
63 Scopus citations -
Phospholipase C is involved in the adenosine-activated signal transduction pathway conferring protection against iodoacetic acid-induced injury in primary rat neuronal cultures
Rogel, A., Bromberg, Y., Sperling, O. & Zoref-Shani, E., 20 Jan 2005, In: Neuroscience Letters. 373, 3, p. 218-221 4 p.Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
2004
Clinical and biochemical manifestations and molecular characterization of the mutation HPRT Jerusalem
Zoref-Shani, E., Bromberg, Y., Hirsch, J., Feinstein, S., Frishberg, Y. & Sperling, O., 2004, In: Nucleosides, Nucleotides and Nucleic Acids. 23, 8-9, p. 1165-1168 4 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
2003
A novel point mutation (I137T) in the conserved 5-phosphoribosyl-1-pyrophosphate binding motif of hypoxanthine-guanine phosphoribosyltransferase (HPRTJerusalem) in a variant of Lesch-Nyhan syndrome
Zoref-Shani, E., Bromberg, Y., Hirsch, J., Feinstein, S., Frishberg, Y. & Sperling, O., 1 Feb 2003, In: Molecular Genetics and Metabolism. 78, 2, p. 158-161 4 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
Protein kinase C-ε is involved in the adenosine-activated signal transduction pathway conferring protection against ischemia-reperfusion injury in primary rat neuronal cultures
Di-Capua, N., Sperling, O. & Zoref-Shani, E., Jan 2003, In: Journal of Neurochemistry. 84, 2, p. 409-412 4 p.Research output: Contribution to journal › Article › peer-review
Open Access59 Scopus citations -
Reactive oxygen species play an important role in iodoacetate-induced neurotoxicity in primary rat neuronal cultures and in differentiated PC12 cells
Sperling, O., Bromberg, Y., Oelsner, H. & Zoref-Shani, E., 20 Nov 2003, In: Neuroscience Letters. 351, 3, p. 137-140 4 p.Research output: Contribution to journal › Article › peer-review
29 Scopus citations -
2002
Activated macrophages for treating skin ulceration: Gene expression in human monocytes after hypo-osmotic shock
Frenkel, O., Shani, E., Ben-Bassat, I., Brok-Simoni, F., Rozenfeld-Granot, G., Kajakaro, G., Rechavi, G., Amariglio, N., Shinar, E. & Danon, D., 2002, In: Clinical and Experimental Immunology. 128, 1, p. 59-66 8 p.Research output: Contribution to journal › Article › peer-review
Open Access27 Scopus citations -
2001
Activation of human monocytes/macrophages by hypo-osmotic shock
Frenkel, O., Shani, E., Ben-Bassat, I., Brok-Simoni, F., Shinar, E. & Danon, D., 2001, In: Clinical and Experimental Immunology. 124, 1, p. 103-109 7 p.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
Decelerated rate of dendrite outgrowth from dopaminergic neurons in primary cultures from brains of hypoxanthine phosphoribosyltransferase-deficient knockout mice
Boer, P., Brosh, S., Wasserman, L., Hammel, I., Zoref-Shani, E. & Sperling, O., 27 Apr 2001, In: Neuroscience Letters. 303, 1, p. 45-48 4 p.Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
Purine nucleosides protect injured neurons and stimulate neuronal regeneration by intracellular and membrane receptor-mediated mechanisms
Di Iorio, P., Caciagli, F., Giuliani, P., Ballerini, P., Ciccarelli, R., Sperling, O., Zoref-Shani, E., Benowitz, L., Traversa, U., Bombi, G., Florio, T., Virgilio, A., Andrew, C. M., Crocker, C. E., Werstiuk, E. S., Middlemiss, P. J. & Rathbone, M. P., 2001, In: Drug Development Research. 52, 1-2, p. 303-315 13 p.Research output: Contribution to journal › Article › peer-review
25 Scopus citations -
Purine nucleotide metabolism in cultured neurons and astroglia from HPRT-deficient knockout mice
Shani, E., Boer, P., Brosh, S., Pelled, D., Bromberg, Y. & Sperling, O., Mar 2001, In: Italian Journal of Biochemistry. 50, 1-2, p. 9-13 5 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
2000
Elevated UTP and CTP content in cultured neurons from HPRT-deficient transgenic mice
Brosh, S., Boer, P., Sperling, O. & Zoref-Shani, E., 2000, In: Journal of Molecular Neuroscience. 14, 1-2, p. 87-91 5 p.Research output: Contribution to journal › Article › peer-review
16 Scopus citations -
Ischemic tolerance conferred to cultured rat neurons by heat shock is not mediated by opening of adenosine triphosphate-sensitive potassium channels
Reshef, A., Capua, N. D., Sperling, O. & Zoref-Shani, E., 30 Jun 2000, In: Neuroscience Letters. 287, 3, p. 223-226 4 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
Kelley-Seegmiller syndrome due to a unique variant of hypoxanthine-guanine phosphoribosyltransferase: Reduced affinity for 5-phosphoribosyl-1-pyrophosphate manifested only at low, physiological substrate concentrations
Zoref-Shani, E., Feinstein, S., Frishberg, Y., Bromberg, Y. & Sperling, O., 21 Feb 2000, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1500, 2, p. 197-203 7 p.Research output: Contribution to journal › Article › peer-review
Open Access27 Scopus citations -
Opening of K(ATP) channels is mandatory for acquisition of ischemic tolerance by adenosine
Reshef, A., Sperling, O. & Zoref-Shani, E., 2000, In: NeuroReport. 11, 3, p. 463-465 3 p.Research output: Contribution to journal › Article › peer-review
31 Scopus citations -
Role of KATP channels in the induction of ischemic tolerance by the 'adenosine mechanism' in neuronal cultures
Reshef, A., Sperling, O. & Zoref-Shani, E., 2000, In: Advances in Experimental Medicine and Biology. 486, p. 217-221 5 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
The adenosine-induced mechanism for the acquisition of ischemic tolerance in primary rat neuronal cultures
Reshef, A., Sperling, O. & Zoref-Shani, E., Aug 2000, In: Pharmacology and Therapeutics. 87, 2-3, p. 151-159 9 p.Research output: Contribution to journal › Article › peer-review
27 Scopus citations -
1999
Abnormal purine and pyrimidine nucleotide content in primary astroglia cultures from hypoxanthine-guanine phosphoribosyltransferase-deficient transgenic mice
Pelled, D., Sperling, O. & Zoref-Shani, E., 1999, In: Journal of Neurochemistry. 72, 3, p. 1139-1145 7 p.Research output: Contribution to journal › Article › peer-review
35 Scopus citations -
1998
Adenosine-induced preconditioning of rat neuronal cultures against ischemia-reperfusion injury
Reshef, A., Sperling, O. & Zoref-Shani, E., 1998, In: Advances in Experimental Medicine and Biology. 431, p. 365-368 4 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
Antiproliferative and differentiating effects of benzodiazepine receptor ligands on B16 melanoma cells
Landau, M., Weizman, A., Zoref-Shani, E., Beery, E., Wasseman, L., Landau, O., Gavish, M., Brenner, S. & Nordenberg, J., 15 Oct 1998, In: Biochemical Pharmacology. 56, 8, p. 1029-1034 6 p.Research output: Contribution to journal › Article › peer-review
67 Scopus citations -
Opening of ATP-sensitive potassium channels by cromakalim confers tolerance against chemical ischemia in rat neuronal cultures
Reshef, A., Sperling, O. & Zoref-Shani, E., 19 Jun 1998, In: Neuroscience Letters. 250, 2, p. 111-114 4 p.Research output: Contribution to journal › Article › peer-review
52 Scopus citations -
1997
Activation and inhibition of protein kinase C protect rat neuronal cultures against ischemia-reperfusion insult
Reshef, A., Sperling, O. & Zoref-Shani, E., 28 Nov 1997, In: Neuroscience Letters. 238, 1-2, p. 37-40 4 p.Research output: Contribution to journal › Article › peer-review
24 Scopus citations -
1996
Adenine nucleotide metabolism in primary rat neuronal cultures
Brosh, S., Zoref-Shani, E., Danziger, E., Bromberg, Y., Sperling, O. & Sidi, Y., Mar 1996, In: International Journal of Biochemistry and Cell Biology. 28, 3, p. 319-328 10 p.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
Preconditioning of primary rat neuronal cultures against ischemic injury: Characterization of the 'time window of protection'
Reshef, A., Sperling, O. & Zoref-Shani, E., 25 Nov 1996, In: Brain Research. 741, 1-2, p. 252-257 6 p.Research output: Contribution to journal › Article › peer-review
41 Scopus citations -
1995
Developmental changes in purine nucleotide metabolism in cultured rat astroglia
Zoref-Shani, E., Bromberg, Y., Lilling, G., Gozes, I., Brosh, S., Sidi, Y. & Sperling, O., Dec 1995, In: International Journal of Developmental Neuroscience. 13, 8, p. 887-896 10 p.Research output: Contribution to journal › Article › peer-review
30 Scopus citations -
1994
Effects of differentiation-inducing agents on purine nucleotide metabolism in an ovarian cancer cell line
Zoref-Shani, E., Lavie, R., Bromberg, Y., Beery, E., Sidi, Y., Sperling, O. & Nordenberg, J., Dec 1994, In: Journal of Cancer Research and Clinical Oncology. 120, 12, p. 717-722 6 p.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
The GDP-bound form of the small G protein Rac1 p21 is a potent activator of the superoxide-forming NADPH oxidase of macrophages
Bromberg, Y., Shani, E., Joseph, G., Gorzalczany, Y., Sperling, O. & Pick, E., 1994, In: Journal of Biological Chemistry. 269, 10, p. 7055-7058 4 p.Research output: Contribution to journal › Article › peer-review
59 Scopus citations -
1993
Characterization of the Alterations in Purine Nucleotide Metabolism in Hypoxanthine‐Guardne Phosphoribosyltransferase‐Deficient Rat Neuroma Cell Line
Zoref‐Shani, E., Bromberg, Y., Brosh, S., Sidi, Y. & Sperling, O., Aug 1993, In: Journal of Neurochemistry. 61, 2, p. 457-463 7 p.Research output: Contribution to journal › Article › peer-review
38 Scopus citations -
1992
Metabolic fate of hypoxanthine and inosine in cultured cardiomyocytes
Zoref-Shani, E., Bromberg, Y., Shirin, C., Sidi, Y. & Sperling, O., Feb 1992, In: Journal of Molecular and Cellular Cardiology. 24, 2, p. 183-189 7 p.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
1991
Hypoxanthine and inosine metabolism in cultured rat cardiomyocytes
Zoref-Shani, E., Bromberg, Y., Shirin, C., Sidi, Y. & Sperling, O., 1991, In: Advances in Experimental Medicine and Biology. 309, Part A, p. 321-325 5 p.Research output: Contribution to journal › Article › peer-review
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1989
AMP catabolism in primary rat cardiomyocyte cultures.
Zoref-Shani, E., Kessler-Icekson, G. & Sperling, O., 1989, In: Advances in Experimental Medicine and Biology. 253 A, p. 359-362 4 p.Research output: Contribution to journal › Article › peer-review
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Prenatal diagnosis of Lesch‐Nyhan syndrome: Experience with three fetuses at risk
Zoref‐Shani, E., Bromberg, Y., Goldman, B., Shaki, R., Barkai, G., Legum, C. & Sperling, O., Sep 1989, In: Prenatal Diagnosis. 9, 9, p. 657-661 5 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
1988
Pathways of adenine nucleotide catabolism in primary rat cardiomyocyte cultures
Zoref-Shani, E., Kessler-Icekson, G. & Sperling, O., Jan 1988, In: Journal of Molecular and Cellular Cardiology. 20, 1, p. 23-33 11 p.Research output: Contribution to journal › Article › peer-review
31 Scopus citations -
1987
Pathways of adenine nucleotide catabolism in primary rat muscle cultures
Zoref-Shani, E., Shainberg, A. & Sperling, O., 7 Dec 1987, In: Biochimica et Biophysica Acta - General Subjects. 926, 3, p. 287-295 9 p.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
1986
Production and degradation of AMP in cultured rat skeletal and heart muscle: a comparative study.
Zoref-Shani, E., Shainberg, A., Kessler-Icekson, G. & Sperling, O., 1986, In: Advances in Experimental Medicine and Biology. 195 Pt B, p. 485-491 7 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
1984
Characterization of purine nucleotide metabolism in primary rat cardiomyocyte cultures
Zoref-Shani, E., Kessler-Icekson, G., Wasserman, L. & Sperling, O., 19 Jun 1984, In: BBA - Molecular Cell Research. 804, 2, p. 161-168 8 p.Research output: Contribution to journal › Article › peer-review
29 Scopus citations -
Lesch-Nyhan syndrome: Biochemical characterization of a case with attenuated behavioral manifestation
Fattal, A., Spirer, Z., Zoref-Shani, E. & Sperling, O., 1984, In: Enzyme. 31, 1, p. 55-60 6 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
Purine nucleotide metabolism in primary rat skeletal muscle cultures.
Zoref-Shani, E., Shainberg, A. & Sperling, O., 1984, In: Advances in Experimental Medicine and Biology. 165 Pt B, p. 425-429 5 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
1983
Alterations in purine nucleotide metabolism during muscle differentiation in vitro
Zoref-Shani, E., Shainberg, A. & Sperling, O., 31 Oct 1983, In: Biochemical and Biophysical Research Communications. 116, 2, p. 507-512 6 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
1982
Characterization of purine nucleotide metabolism in primary rat muscle cultures
Zoref-Shani, E., Shainberg, A. & Sperling, O., 16 Jun 1982, In: Biochimica et Biophysica Acta - General Subjects. 716, 3, p. 324-330 7 p.Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
De novo purine synthesis in skeletal muscle
Brosh, S., Boer, P., Zoref-Shani, E. & Sperling, O., 12 Jan 1982, In: Biochimica et Biophysica Acta - General Subjects. 714, 1, p. 181-183 3 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
Juvenile metabolic gout caused by chronic compensated hemolytic syndrome
Liberman, U. A., Samuel, R., Halabe, A., Joshua, H., Lubin, E., Zoref‐Shani, E. & Sperling, O., Oct 1982, In: Arthritis and Rheumatology. 25, 10, p. 1264-1266 3 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Lesch-Nyhan syndrome in an Arab family. Detection and biochemical manifestation of heterozygosity
Shaltiel, A., Katzuni, E., Boer, P., Zoref-Shani, E. & Sperling, O., 1982, In: Israel Journal of Medical Sciences. 17, 12, p. 1169-1173 5 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
1980
Characterization of purine nucleotide metabolism in cultured fibroblasts with deficiency of hypoxanthine-guanine phosphoribosyltransferase and with superactivity of phosphoribosylpyrophosphate synthetase
Zoref-Shani, E. & Sperling, O., 1980, In: Enzyme. 25, 6, p. 413-418 6 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations