Personal profile
Research interests
T cell engineering, Immunotherapy
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Dive into the research topics where Eric Shifrut is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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The role of the SLC25A15 transporter in the formation of liver metastasis in ESR1-mutated breast cancer
Taya, M., Fishman, D., Kanani, F., Zinger, L., Merenbakh-Lamin, K., Elfasi Sosner, S., Shendge, A. K., Klein Goldberg, A., Wolf, U., Winkler, G., Shifrut, E., Cohen, S., Wolf, I., Sekler, I. & Rubinek, T., 18 Feb 2026, In: Oncogene. 45, 5, p. 603-619 17 p.Research output: Contribution to journal › Article › peer-review
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Crosslinking of Ly6a metabolically reprograms CD8 T cells for cancer immunotherapy
Maliah, A., Santana-Magal, N., Parikh, S., Gordon, S., Reshef, K., Sade, Y., Khateeb, A., Richter, A., Gutwillig, A., Parikh, R., Golan, T., Krissi, M., Na, M., Binshtok, G., Manich, P., Elkoshi, N., Grisaru-Tal, S., Zemser-Werner, V., Brenner, R. & Vaknine, H. & 12 others, , Dec 2024, In: Nature Communications. 15, 1, 8354.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Method of moments framework for differential expression analysis of single-cell RNA sequencing data
Kim, M. C., Gate, R., Lee, D. S., Tolopko, A., Lu, A., Gordon, E., Shifrut, E., Garcia-Nieto, P. E., Marson, A., Ntranos, V. & Ye, C. J., 31 Oct 2024, In: Cell. 187, 22, p. 6393-6410.e16Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
TIM-3, LAG-3, or 2B4 gene disruptions increase the anti-tumor response of engineered T cells
Cianciotti, B. C., Magnani, Z. I., Ugolini, A., Camisa, B., Merelli, I., Vavassori, V., Potenza, A., Imparato, A., Manfredi, F., Abbati, D., Perani, L., Spinelli, A., Shifrut, E., Ciceri, F., Vago, L., Di Micco, R., Naldini, L., Genovese, P., Ruggiero, E. & Bonini, C., 2024, In: Frontiers in Immunology. 15, 1315283.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
High-yield genome engineering in primary cells using a hybrid ssDNA repair template and small-molecule cocktails
Shy, B. R., Vykunta, V. S., Ha, A., Talbot, A., Roth, T. L., Nguyen, D. N., Pfeifer, W. G., Chen, Y. Y., Blaeschke, F., Shifrut, E., Vedova, S., Mamedov, M. R., Chung, J. Y. J., Li, H., Yu, R., Wu, D., Wolf, J., Martin, T. G., Castro, C. E. & Ye, L. & 3 others, , Apr 2023, In: Nature Biotechnology. 41, 4, p. 521-531 11 p.Research output: Contribution to journal › Article › peer-review
Open Access148 Scopus citations