Avishay Stark

2006

Astrocyte control of fetal cortical neuron glutathione homeostasis: Up-regulation by ethanol

Rathinam, M. L., Watts, L. T., Stark, A. A., Mahimainathan, L., Stewart, J., Schenker, S. & Henderson, G. I., Mar 2006, In: Journal of Neurochemistry. 96, 5, p. 1289-1300 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

53 Scopus citations

2005

Threat assessment of mycotoxins as weapons: Molecular mechanisms of acute toxicity

Stark, A. A., Jun 2005, In: Journal of Food Protection. 68, 6, p. 1285-1293 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

32 Scopus citations

2003

The role of γ-glutamyl transpeptidase in the biosynthesis of glutathione

Stark, A. A., Porat, N., Volohonsky, G., Komlosh, A., Bluvshtein, E., Tubi, C. & Steinberg, P., 2003, In: BioFactors. 17, 1-4, p. 139-149 11 p.

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

2002

A spectrophotometric assay of γ-glutamylcysteine synthetase and glutathione synthetase in crude extracts from tissues and cultured mammalian cells

Volohonsky, G., Tuby, C. N. Y. H., Porat, N., Wellman-Rousseau, M., Visvikis, A., Leroy, P., Rashi, S., Steinberg, P. & Stark, A. A., 20 Apr 2002, In: Chemico-Biological Interactions. 140, 1, p. 49-65 17 p.

Research output: Contribution to journal › Article › peer-review

34 Scopus citations

gamma-Glutamyl transpeptidase and glutathione biosynthesis in non-tumorigenic and tumorigenic rat liver oval cell lines.

Komlosh, A., Volohonsky, G., Porat, N., Tuby, C., Bluvshtein, E., Steinberg, P., Oesch, F. & Stark, A. A., Apr 2002, In: Carcinogenesis. 23, 4, p. 671-678 8 p.

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

2001

High-performance liquid chromatographic assay of hydroxyl free radical using salicylic acid hydroxylation during in vitro experiments involving thiols

Diez, L., Livertoux, M. H., Stark, A. A., Wellman-Rousseau, M. & Leroy, P., 5 Nov 2001, In: Journal of Chromatography B: Biomedical Sciences and Applications. 763, 1-2, p. 185-193 9 p.

Research output: Contribution to journal › Article › peer-review

107 Scopus citations

γ-glutamyl transpeptidase and glutathione biosynthesis in non-tumorigenic and tumorigenic rat liver oval cell lines

Komlosh, A., Volohonsky, G., Porat, N., Tuby, C., Bluvshtein, E., Steinberg, P., Oesch, F. & Stark, A. A., 2001, In: Carcinogenesis. 22, 12, p. 2009-2016 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

1999

Inhibition of the hydrolytic and transpeptidase activities of rat kidney γ-glutamyl transpeptidase by specific monoclonal antibodies

Bluvshtein, E., Glass, G. A., Volohonsky, G., Yaakubowitz, M., Harness, E., Smorodinsky, N. I., Seidel, A., Frank, H., Steinberg, P. & Stark, A. A., 15 Mar 1999, In: European Journal of Biochemistry. 260, 3, p. 844-854 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

1998

Transient appearance of the mutator phenotype during carcinogenesis as a possible explanation for the lack of mini/microsatellite instability in many late stage tumors

Stark, A. A., 3 Nov 1998, In: Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 421, 2, p. 221-225 5 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

γ-Glutamyl transpeptidase-dependent mutagenicity and cytotoxicity of γ-Glutamyl derivatives: A model for biochemical targeting of chemotherapeutic agents

Keren, R. & Stark, A. A., 1998, In: Environmental and Molecular Mutagenesis. 32, 4, p. 377-386 10 p.

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

1997

Promotion of glutathione-γ-glutumyl transpeptidase-dependent lipid peroxidation by copper and ceruloplasmin: The requirement for iron and the effects of antioxidants and antioxidant enzymes

Glass, G. A. & Stark, A. A., 1997, In: Environmental and Molecular Mutagenesis. 29, 1, p. 73-80 8 p.

Research output: Contribution to journal › Article › peer-review

39 Scopus citations

Role of copper and ceruloplasmin in oxidative mutogenesis induced by the glutathione-γ-glutamyl transpeptidase system and by other thiols

Stark, A. A. & Glass, G. A., 1997, In: Environmental and Molecular Mutagenesis. 29, 1, p. 63-72 10 p.

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

1996

Structure-activity relationships in the mutagenicity and cytotoxicity of putative metabolites and related analogs of benzene derived from the valence tautomers benzene oxide and oxepin

Stark, A. A. & Rastetter, W. H., 1996, In: Environmental and Molecular Mutagenesis. 28, 3, p. 284-293 10 p.

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

The role of chelators in the catalysis of glutathione-γ-glutamyl transpeptidase-dependent lipid peroxidation by transition metals

Zalit, I., Glass, G. A. & Stark, A. A., Dec 1996, In: Biochemistry and Molecular Biology International. 40, 6, p. 1123-1133 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

1994

Detection of conformational changes in rat kidney gamma-glutamyl transpeptidase by an antibody against a synthetic peptide belonging to part of the reactive centre of the enzyme

Glass, G. A., Bluvshtein, E., Gur, Y., Sfez, S., Simovich, V. & Stark, A. A., 1994, In: Biochemistry and Molecular Biology International. 33, 3, p. 505-513 9 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Localization of oxidative damage by a glutathione-γ-glutamyl transpeptidase system in preneoplastic lesions in sections of livers from carcinogen-treated rats

Stark, A. A., Russell, J. J., Langenbach, R., Pagano, D. A., Zeiger, E. & Huberman, E., Feb 1994, In: Carcinogenesis. 15, 2, p. 343-348 6 p.

Research output: Contribution to journal › Article › peer-review

73 Scopus citations

The effects of antioxidants and enzymes involved in glutathione metabolism in mutagenesis by glutathione and l-cysteine

Stark, A. A., Pagano, D. A., Glass, G., Kamin-Belsky, N. & Zeiger, E., 16 Jul 1994, In: Mutation Research Regular Papers. 308, 2, p. 215-222 8 p.

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

1993

Glutathione metabolism by γ-glutamyltranspeptidase leads to lipid peroxidation: Characterization of the system and relevance to hepatocarcinogenesis

Stark, A. A., Zeiger, E. & Pagano, D. A., Feb 1993, In: Carcinogenesis. 14, 2, p. 183-189 7 p.

Research output: Contribution to journal › Article › peer-review

112 Scopus citations

1991

Synergism between aflatoxins in covalent binding to DNA and in mutagenesis in the photoactivation system

Stark, A. A. & Liberman, D. F., Mar 1991, In: Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 247, 1, p. 77-86 10 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

1990

Autoxidation and mutagenicity of sodium bisulfite

Pagano, D. A., Zeiger, E. & Stark, A. A., Jan 1990, In: Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 228, 1, p. 89-96 8 p.

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

Human cytochrome p450iia3: Cdna sequence role of the enzyme in the metabolic of promutagens comparison to nitrosamine activation by human cytochrome p450iie1

Crespi, C. L., Penman, B. W., Leakey, J. A. E., Arlotto, M. P., Stark, A., Parkinson, A., Turner, T., Steimel, D. T., Rudo, K., Davies, R. L. & Langenbach, R., Aug 1990, In: Carcinogenesis. 11, 8, p. 1293-1300 8 p.

Research output: Contribution to journal › Article › peer-review

161 Scopus citations

Involvement of singlet oxygen in photoactivation of aflatoxins B₁ and B₂ to DNA-binding forms in vitro

Stark, A. A., Gal, Y. & Shaulsky, G., Apr 1990, In: Carcinogenesis. 11, 4, p. 529-534 6 p.

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Properties of aflatoxin-DNA adducts formed by photoactivation and characterization of the major photoadduct as aflatoxin-N⁷-guanine

Shaulsky, G., Johnson, R. L., Shockcor, J. P., Taylor, L. C. E. & Stark, A. A., Apr 1990, In: Carcinogenesis. 11, 4, p. 519-527 9 p.

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Structure-activity relationships in mutagenicity and in nucleophilic ring opening of N-(arylmethy)phenanthrene 9, 10-imines

Roll, M., Shtelzer, S., Stark, A. A. & Blum, J., Jan 1990, In: Mutagenesis. 5, 1, p. 25-30 6 p.

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

1989

Effect of pH on mutagenesis by thiols in Salmonella typhimurium TA102

Stark, A. A., Arad, A., Siskindovich, S., Pagano, D. A. & Zeiger, E., Sep 1989, In: Mutation Research - Genetic Toxicology Testing and Biomonitoring of Environmental or Occupational Exposure. 224, 1, p. 89-94 6 p.

Research output: Contribution to journal › Article › peer-review

45 Scopus citations

1988

DNA Strand Scission and Apurinic Sites Induced by Photoactivated Aflatoxins

Stark, A. A., Malca-Mor, L., Herman, Y. & Liberman, D. F., 1988, In: Cancer Research. 48, 11, p. 3070-3076 7 p.

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Glutathione mutagenesis in salmonella typhimurium is a γ-glutamyltranspeptidase-enhanced process involving active oxygen species

Stark, A. A., Zeiger, E. & Pagano, D. A., May 1988, In: Carcinogenesis. 9, 5, p. 771-777 7 p.

Research output: Contribution to journal › Article › peer-review

55 Scopus citations

1987

Glutathione mutagenesis in Salmonella typhimurium TA100: Dependence on a single enzyme, γ-glutamyltranspeptidase

Stark, A. A., Zeiger, E. & Pagano, D. A., Mar 1987, In: Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 177, 1, p. 45-52 8 p.

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

1986

Structure-activity relationships in the mutagenicity of N-substituted derivatives of phenanthrene-9,10-imine

Stark, A. A., Zeiger, E., Shtelzer, S., Sheradsky, T., Lifshitz, Y. & Blum, J., 1986, In: Mutagenesis. 1, 1, p. 35-39 5 p.

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

γ-glutamyltranspeptidase in murine lymphomas

Stark, A. A., Hochman, J., Levy, E., Barr-Nea, L., Goldschmied-Reouven, A. & Amizur, M., Jan 1986, In: European Journal of Cancer and Clinical Oncology. 22, 1, p. 77-87 11 p.

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

1984

Comparative Aflatoxin B₁ Mutagenesis of Salmonella typhimurium TA100 in Metabolic and Photoactivation Systems

Israel-Kalinsky, H., Malca-Mor, L. & Stark, A. A., 1 May 1984, In: Cancer Research. 44, 5, p. 1831-1839 9 p.

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

1983

Genetic transformation of obligately chemolithotrophic thiobacilli

Yankofsky, S. A., Gurevich, R., Grimland, N. & Stark, A. A., 1983, In: Journal of Bacteriology. 153, 2, p. 652-657 6 p.

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Mutagenesis in Streptococcus pneumoniae (Pneumococcus) by transformation with DNA modified by the carcinogen-mutagen, aflatoxin B₁

Stark, A. A. & Giroux, C. N., Jan 1983, In: Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 107, 1, p. 23-32 10 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

1982

Mutagenicity and cytotoxicity of the carcinogen-mutagen aflatoxin B₁ in Streptococcus pneumoniae (Pneumococcus) and Salmonella typhimurium: dependence on DNA repair functions

Stark, A. A. & Giroux, C. N., Dec 1982, In: Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 106, 2, p. 195-208 14 p.

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Mutagenicity and toxicity of carcinogenic and other hydrazine derivatives: Correlation between toxic potency in animals and toxic potency in Salmonella typhimurium TA1538

Malca-Mor, L. & Stark, A. A., 1982, In: Applied and Environmental Microbiology. 44, 4, p. 801-808 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

28 Scopus citations

Mutagenicity of anthraquinone and hydroxylated anthraquinones in the Ames/Salmonella microsome system

Liberman, D. F., Fink, R. C., Schaefer, F. L., Mulcahy, R. J. & Stark, A. A., 1982, In: Unknown Journal. 43, 6, p. 1354-1359 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

39 Scopus citations

Photoactivated aflatoxins are mutagens to salmonella typhimurium and bind covalently to DNA in vitro

Israel-kalinsky, H., Tuch, J., Roitelman, J. & Stark, A. A., 1982, In: Carcinogenesis. 3, 4, p. 423-429 7 p.

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

1981

Active transport of amino acids in Thiobacillus thioparus is a low-affinity process

Stark, A. A. & Yankofsky, S. A., 1981, In: Journal of Bacteriology. 148, 3, p. 956-965 10 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Regulation of amino acid transport in Thiobacillus thioparus

Stark, A. A. & Yankofsky, S. A., 1981, In: Journal of Bacteriology. 148, 3, p. 966-972 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

1979

Aflatoxin B₁ mutagenesis, DNA binding, and adduct formation in Salmonella typhimurium

Stark, A. A., Essigmann, J. M. & Demain, A. L., 1979, In: Proceedings of the National Academy of Sciences of the United States of America. 76, 3, p. 1343-1347 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

58 Scopus citations

Plate diffusion assay as a rapid method for dosimetry of mutagens

Awerbuch, T. E. & Stark, A. A., 1979, In: Applied and Environmental Microbiology. 38, 6, p. 1127-1131 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

1978

Mollicellins: Mutagenic and antibacterial mycotoxins

Stark, A. A., Kobbe, B., Matsuo, K., Büchi, G., Wogan, G. N. & Demain, A. L., 1978, In: Unknown Journal. 36, 3, p. 412-420 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

16 Scopus citations

Mutagenicity and antibacterial activity of mycotoxins produced by Penicillium islandicum Sopp and Penicillium rugulosum

Stark, A. A., Townsend, J. M., Wogan, G. N., Demain, A. L., Manmade, A. & Ghosh, A. C., 1978, In: Unknown Journal. 2, 2, p. 313-324 12 p.

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Avishay Stark

Research output

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