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Aldema Sas-Chen

Doctor

 https://orcid.org/0000-0002-0347-6173
20062025

Research activity per year

Personal profile

Research interests

Epitranscriptome, RNA modifications, non-coding RNA, transcription regulation, cancer, metastasis, human disease. We are investigating RNA based regulatory mechanisms involved in health and disease, focusing on roles of non-coding RNAs and the epitranscriptome

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  • A sequence-specific RNA acetylation catalyst

    Gamage, S. T., Manage, S. H., Sas-Chen, A., Nir, R., Burkhart, B. W., Jhulki, I., Link, C. N., Penikalapati, M. S., Jones, J. E., Iyer, L. M., Aravind, L., Santangelo, T. J., Schwartz, S. & Meier, J. L., 11 Apr 2025, In: Nucleic Acids Research. 53, 6, gkaf217.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1 Scopus citations

  • High-throughput detection of RNA modifications at single base resolution

    Ron, K., Kahn, J., Malka-Tunitsky, N. & Sas-Chen, A., Jan 2025, In: FEBS Letters. 599, 1, p. 19-32 14 p.

    Research output: Contribution to journal › Review article › peer-review

    Open Access
    2 Scopus citations

  • Role of RNA modifications in cancer metastasis

    Malka-Tunitsky, N. & Sas-Chen, A., Aug 2024, In: Current Opinion in Genetics and Development. 87, 102232.

    Research output: Contribution to journal › Review article › peer-review

    6 Scopus citations

  • A late-stage assembly checkpoint of the human mitochondrial ribosome large subunit

    Rebelo-Guiomar, P., Pellegrino, S., Dent, K. C., Sas-Chen, A., Miller-Fleming, L., Garone, C., Van Haute, L., Rogan, J. F., Dinan, A., Firth, A. E., Andrews, B., Whitworth, A. J., Schwartz, S., Warren, A. J. & Minczuk, M., Dec 2022, In: Nature Communications. 13, 1, 929.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    33 Scopus citations

  • Antisense pairing and SNORD13 structure guide RNA cytidine acetylation

    Gamage, S. T., Bortolin-Cavaillé, M. L., Link, C., Bryson, K., Sas-Chen, A., Schwartz, S., Cavaillé, J. & Meier, J. L., Dec 2022, In: RNA. 28, 12, p. 1582-1596 15 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    24 Scopus citations
View all 26 Research outputs