Human Molecular Genetics Biochemistry

2025

A compendium of Amplification-Related Gain Of Sensitivity genes in human cancer

Rendo, V., Schubert, M., Khuu, N., Suarez Peredo Rodriguez, M. F., Whyte, D., Ling, X., van den Brink, A., Huang, K., Swift, M., He, Y., Zerbib, J., Smith, R., Raaijmakers, J., Bandopadhayay, P., Guenther, L. M., Hwang, J. H., Iniguez, A., Moody, S., Seo, J. H. & Stover, E. H. & 9 others, Garraway, L., Hahn, W. C., Stegmaier, K., Medema, R. H., Chowdhury, D., Colomé-Tatché, M., Ben-David, U., Beroukhim, R. & Foijer, F., Dec 2025, In: Nature Communications. 16, 1, 1077.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Allosteric modulation of NF1 GAP: Differential distributions of catalytically competent populations in loss-of-function and gain-of-function mutants

Xu, L., Jang, H. & Nussinov, R., Feb 2025, In: Protein Science. 34, 2, e70042.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

A new class of type VI secretion system effectors can carry two toxic domains and are recognized through the WHIX motif for export

Fridman, C. M., Keppel, K., Rudenko, V., Altuna-Alvarez, J., Albesa-Jové, D., Bosis, E. & Salomon, D., Mar 2025, In: PLoS Biology. 23, 3 March, e3003053.

Research output: Contribution to journal › Article › peer-review

Open Access

Broad repression of DNA repair genes in senescent cells identified by integration of transcriptomic data

Frey, Y., Haj, M., Ziv, Y., Elkon, R. & Shiloh, Y., 13 Jan 2025, In: Nucleic Acids Research. 53, 1, gkae1257.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Copy Number Variation and Haplotype Analysis of 17q21.31 Reveals Increased Risk Associated with Progressive Supranuclear Palsy and Gene Expression Changes in Neuronal Cells

PSP Genetics Study Group, 2025, (Accepted/In press) In: Movement Disorders.

Research output: Contribution to journal › Article › peer-review

Open Access

DeepDrug as an expert guided and AI driven drug repurposing methodology for selecting the lead combination of drugs for Alzheimer’s disease

Li, V. O. K., Han, Y., Kaistha, T., Zhang, Q., Downey, J., Gozes, I. & Lam, J. C. K., Dec 2025, In: Scientific Reports. 15, 1, 2093.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Deep learning-based cell-specific gene regulatory networks inferred from single-cell multiome data

Xu, J., Lu, C., Jin, S., Meng, Y., Fu, X., Zeng, X., Nussinov, R. & Cheng, F., 24 Mar 2025, In: Nucleic Acids Research. 53, 5, gkaf138.

Research output: Contribution to journal › Article › peer-review

Open Access

Distinct Allosteric Networks in CDK4 and CDK6 in the Cell Cycle and in Drug Resistance

Zhang, W., Bradburn, D., Heidebrink, G., Liu, Y., Jang, H., Nussinov, R. & Kõivomägi, M., 2025, (Accepted/In press) In: Journal of Molecular Biology. 169121.

Research output: Contribution to journal › Article › peer-review

Open Access

Enhancing cognitive function after traumatic brain injury in male mice: The benefits of running regardless of intervention timing

Tseitlin, L., Schreiber, S., Richmond-Hacham, B., Bikovski, L. & Pick, C. G., Feb 2025, In: Experimental Neurology. 384, 115069.

Research output: Contribution to journal › Article › peer-review

Epidemiology and Trends of Cutaneous Fungal Infections (2019–2022) in Israel: A Single Tertiary-Center Study

Galili, E., Taieb, A., Shemer, A., Leor, G., Lyakhovitsky, A., Barzilai, A. & Baum, S., Apr 2025, In: Journal of Fungi. 11, 4, 320.

Research output: Contribution to journal › Article › peer-review

Open Access

ERK Allosteric Activation: The Importance of Two Ordered Phosphorylation Events

Regev, C., Jang, H. & Nussinov, R., 2025, (Accepted/In press) In: Journal of Molecular Biology. 169130.

Research output: Contribution to journal › Article › peer-review

Extremely Low-Frequency and Low-Intensity Electromagnetic Field Technology (ELF-EMF) Sculpts Microtubules

Lobyntseva, A., Ganaiem, M., Ivashko-Pachima, Y., Barnstable, C., Weisinger, B., Parabucki, A., Segal, Y., Shohami, E. & Gozes, I., Feb 2025, In: European Journal of Neuroscience. 61, 4, e70023.

Research output: Contribution to journal › Article › peer-review

Open Access

High CDC20 levels increase sensitivity of cancer cells to MPS1 inhibitors

Zheng, S., Raz, L., Zhou, L., Cohen-Sharir, Y., Tian, R., Ippolito, M. R., Gianotti, S., Saad, R., Wardenaar, R., Broekhuis, M., Rodriguez, M. S. P., Wobben, S., van den Brink, A., Bakker, P., Santaguida, S., Foijer, F. & Ben-David, U., 24 Feb 2025, In: EMBO Reports. 26, 4, p. 1036-1061 26 p.

Research output: Contribution to journal › Article › peer-review

Open Access

HMCN1 variants aggravate epidermolysis bullosa simplex phenotype

Bergson, S., Sarig, O., Giladi, M., Mohamad, J., Mogezel-Salem, M., Smorodinsky-Atias, K., Sade, O., Manori, B., Assaf, S., Malovitski, K., Feller, Y., Pavlovsky, M., Hainzl, S., Kocher, T., Hummel, J. I., Eretz Kdosha, N., Khair, L. G., Zauner, R., Pinon Hofbauer, J. & Shalom-Feuerstein, R. & 7 others, Wally, V., Koller, U., Samuelov, L., Haitin, Y., Ashery, U., Rubinstein, R. & Sprecher, E., 5 May 2025, In: Journal of Experimental Medicine. 222, 5

Research output: Contribution to journal › Article › peer-review

Open Access

Mesenchymal stem cell-derived exosomes mitigate amyloid β-induced retinal toxicity: Insights from rat model and cellular studies

Qarawani, A., Naaman, E., Ben-Zvi Elimelech, R., Harel, M., Sigal-Dror, S., Ben-Zur, T., Ziv, T., Offen, D. & Zayit-Soudry, S., Jan 2025, In: Journal of Extracellular Biology. 4, 1, e70024.

Research output: Contribution to journal › Article › peer-review

Open Access

mTOR Variants Activation Discovers PI3K-like Cryptic Pocket, Expanding Allosteric, Mutant-Selective Inhibitor Designs

Liu, Y., Zhang, W., Jang, H. & Nussinov, R., 27 Jan 2025, In: Journal of Chemical Information and Modeling. 65, 2, p. 966-980 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Patterns of expression and prognostic implication of glycoprotein nonmetastatic protein B (GPNMB) expression in sentinel lymph nodes of melanoma patients

Beitner, A., Abu-Abeid, A., Dayan, D., Gat, A., Miodovnik, M., Levy, C. & Nizri, E., 2025, (Accepted/In press) In: Melanoma Research. 10.1097/CMR.0000000000001019.

Research output: Contribution to journal › Article › peer-review

Re-epithelialization of cancer cells increases autophagy and DNA damage: Implications for breast cancer dormancy and relapse

Drago-Garcia, D., Giri, S., Chatterjee, R., Simoni-Nieves, A., Abedrabbo, M., Genna, A., Uribe Rios, M. L., Lindzen, M., Sekar, A., Gupta, N., Aharoni, N., Bhandari, T., Mayalagu, A., Schwarzmüller, L., Tarade, N., Zhu, R., Mohan-Raju, H. R., Karatekin, F., Roncato, F. & Eyal-Lubling, Y. & 22 others, Keidar, T., Nof, Y., Nataraj, N. B., Bernshtein, K. S., Wagner, B., Nair, N. U., Sanghvi, N., Alon, R., Seger, R., Pikarsky, E., Donzelli, S., Blandino, G., Wiemann, S., Lev, S., Prywes, R., Barkan, D., Rueda, O. M., Caldas, C., Ruppin, E., Shiloh, Y., Dahlhoff, M. & Yarden, Y., 22 Apr 2025, In: Science Signaling. 18, 883, eado3473.

Research output: Contribution to journal › Article › peer-review

Small molecule modulation of p75^NTR engages the autophagy-lysosomal pathway and reduces huntingtin aggregates in cellular and mouse models of Huntington's disease

Simmons, D. A., Alexander, N., Cao, G., Rippin, I., Lugassy, Y., Eldar-Finkelman, H. & Longo, F. M., Mar 2025, In: Neurotherapeutics. 22, 2, e00495.

Research output: Contribution to journal › Article › peer-review

Open Access

The cGAS–STING, p38 MAPK, and p53 pathways link genome instability to accelerated cellular senescence in ATM-deficient murine lung fibroblasts

Haj, M., Frey, Y., Levon, A., Maliah, A., Ben-Yishay, T., Slutsky, R., Smoom, R., Tzfati, Y., Ben-David, U., Levy, C., Elkon, R., Ziv, Y. & Shiloh, Y., 14 Jan 2025, In: Proceedings of the National Academy of Sciences of the United States of America. 122, 2, e2419196122.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

The lactate receptor HCAR1 drives the recruitment of immunosuppressive PMN-MDSCs in colorectal cancer

He, J., Chai, X., Zhang, Q., Wang, Y., Wang, Y., Yang, X., Wu, J., Feng, B., Sun, J., Rui, W., Ze, S., Fu, Y., Zhao, Y., Zhang, Y., Zhang, Y., Liu, M., Liu, C., She, M., Hu, X. & Ma, X. & 18 others, Yang, H., Li, D., Zhao, S., Li, G., Zhang, Z., Tian, Z., Ma, Y., Cao, L., Yi, B., Li, D., Nussinov, R., Eng, C., Chan, T. A., Ruppin, E., Gutkind, J. S., Cheng, F., Liu, M. & Lu, W., Mar 2025, In: Nature Immunology. 26, 3, p. 391-403 13 p., eabi8602.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

2024

271st ENMC international workshop: Towards a unifying effort to fight Kennedy's disease. 20-22 October 2023, Hoofddorp, Netherlands

KD Consortium, May 2024, In: Neuromuscular Disorders. 38, p. 8-19 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

ADNP dysregulates methylation and mitochondrial gene expression in the cerebellum of a Helsmoortel–Van der Aa syndrome autopsy case

D’Incal, C., Van Dijck, A., Ibrahim, J., De Man, K., Bastini, L., Konings, A., Elinck, E., Gozes, L., Marusic, Z., Anicic, M., Vukovic, J., Van der Aa, N., Mateiu, L., Vanden Berghe, W. & Kooy, R. F., Dec 2024, In: Acta neuropathologica communications. 12, 1, 62.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

ADNP is essential for sex-dependent hippocampal neurogenesis, through male unfolded protein response and female mitochondrial gene regulation

Shapira, G., Karmon, G., Hacohen-Kleiman, G., Ganaiem, M., Shazman, S., Theotokis, P., Grigoriadis, N., Shomron, N. & Gozes, I., 2024, (Accepted/In press) In: Molecular Psychiatry. e1166.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

A Foundation Model Identifies Broad-Spectrum Antimicrobial Peptides against Drug-Resistant Bacterial Infection

Li, T., Ren, X., Luo, X., Wang, Z., Li, Z., Luo, X., Shen, J., Li, Y., Yuan, D., Nussinov, R., Zeng, X., Shi, J. & Cheng, F., Dec 2024, In: Nature Communications. 15, 1, 7538.

Research output: Contribution to journal › Article › peer-review

Open Access

16 Scopus citations

Allosteric Activation of RhoA Complexed with p115-RhoGEF Deciphered by Conformational Dynamics

Haspel, N., Jang, H. & Nussinov, R., 12 Feb 2024, In: Journal of Chemical Information and Modeling. 64, 3, p. 862-873 12 p.

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

A molecular video-derived foundation model for scientific drug discovery

Xiang, H., Zeng, L., Hou, L., Li, K., Fu, Z., Qiu, Y., Nussinov, R., Hu, J., Rosen-Zvi, M., Zeng, X. & Cheng, F., Dec 2024, In: Nature Communications. 15, 1, 9696.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

A network-based method for associating genes with autism spectrum disorder

Zadok, N., Ast, G. & Sharan, R., 2024, In: Frontiers in Bioinformatics. 4, 1295600.

Research output: Contribution to journal › Article › peer-review

Open Access

A p62-dependent rheostat dictates micronuclei catastrophe and chromosome rearrangements

Martin, S., Scorzoni, S., Cordone, S., Mazzagatti, A., Beznoussenko, G. V., Gunn, A. L., Di Bona, M., Eliezer, Y., Leor, G., Ben-Yishay, T., Loffreda, A., Cancila, V., Rainone, M. C., Ippolito, M. R., Martis, V., Bedin, F., Garrè, M., Vaites, L. P., Vasapolli, P. & Polo, S. & 9 others, Parazzoli, D., Tripodo, C., Mironov, A. A., Cuomo, A., Ben-David, U., Bakhoum, S. F., Hatch, E. M., Ly, P. & Santaguida, S., 30 Aug 2024, In: Science. 385, 6712, p. eadj7446

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Application of the international criteria for optic neuritis in the Acute Optic Neuritis Network

Klyscz, P., Asseyer, S., Alonso, R., Bereuter, C., Bialer, O., Bick, A., Carta, S., Chen, J. J., Cohen, L., Cohen-Tayar, Y., Carnero Contentti, E., Dale, R. C., Flanagan, E. P., Gernert, J. A., Haas, J., Havla, J., Heesen, C., Hellmann, M., Levin, N. & Lopez, P. & 31 others, Lotan, I., Luis, M. B., Mariotto, S., Mayer, C., Vergara, A. J. M., Ocampo, C., Ochoa, S., Oertel, F. C., Olszewska, M., Uribe, J. L. P., Sastre-Garriga, J., Scocco, D., Ramanathan, S., Rattanathamsakul, N., Shi, F. D., Shifa, J., Simantov, I., Siritho, S., Tiosano, A., Tisavipat, N., Torres, I., Dembinsky, A. V., Vidal-Jordana, A., Wilf-Yarkoni, A., Wu, T., Zamir, S., Zarco, L. A., Zimmermann, H. G., Petzold, A., Paul, F. & Stiebel-Kalish, H., Sep 2024, In: Annals of Clinical and Translational Neurology. 11, 9, p. 2473-2484 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

ATF3 characterizes aggressive drug-tolerant persister cells in HGSOC

Böpple, K., Oren, Y., Henry, W. S., Dong, M., Weller, S., Thiel, J., Kleih, M., Gaißler, A., Zipperer, D., Kopp, H. G., Aylon, Y., Oren, M., Essmann, F., Liang, C. & Aulitzky, W. E., Apr 2024, In: Cell Death and Disease. 15, 4, 290.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

ATM germ line pathogenic variants affect outcomes in children with ataxia-telangiectasia and hematological malignancies

Elitzur, S., Shiloh, R., Loeffen, J. L. C., Pastorczak, A., Takagi, M., Bomken, S., Baruchel, A., Lehrnbecher, T., Tasian, S. K., Abla, O., Arad-Cohen, N., Astigarraga, I., Ben-Harosh, M., Bodmer, N., Brozou, T., Ceppi, F., Chugaeva, L., Dalla Pozza, L., Ducassou, S. & Escherich, G. & 33 others, Farah, R., Gibson, A., Hasle, H., Hoveyan, J., Jacoby, E., Jazbec, J., Junk, S., Kolenova, A., Lazic, J., Lo Nigro, L., Mahlaoui, N., Miller, L., Papadakis, V., Pecheux, L., Pillon, M., Sarouk, I., Stary, J., Stiakaki, E., Strullu, M., Tran, T. H., Ussowicz, M., Verdu-Amoros, J., Wakulinska, A., Zawitkowska, J., Stoppa-Lyonnet, D., Taylor, A. M., Shiloh, Y., Izraeli, S., Minard-Colin, V., Schmiegelow, K., Nirel, R., Attarbaschi, A. & Borkhardt, A., 12 Sep 2024, In: Blood. 144, 11, p. 1193-1205 13 p.

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Beneficial islet inflammation in health depends on pericytic TLR/MyD88 signaling

Schonblum, A., Naser, D. A., Ovadia, S., Egbaria, M., Puyesky, S., Epshtein, A., Wald, T., Mercado-Medrez, S., Ashery-Padan, R. & Landsman, L., 15 Jul 2024, In: Journal of Clinical Investigation. 134, 14, e179335.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Binding Modalities and Phase-Specific Regulation of Cyclin/Cyclin-Dependent Kinase Complexes in the Cell Cycle

Bergman, M. T., Zhang, W., Liu, Y., Jang, H. & Nussinov, R., 3 Oct 2024, In: Journal of Physical Chemistry B. 128, 39, p. 9315-9326 12 p.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Cancer drug-tolerant persister cells: from biological questions to clinical opportunities

Russo, M., Chen, M., Mariella, E., Peng, H., Rehman, S. K., Sancho, E., Sogari, A., Toh, T. S., Balaban, N. Q., Batlle, E., Bernards, R., Garnett, M. J., Hangauer, M., Leucci, E., Marine, J. C., O’Brien, C. A., Oren, Y., Patton, E. E., Robert, C. & Rosenberg, S. M. & 2 others, Shen, S. & Bardelli, A., Oct 2024, In: Nature Reviews Cancer. 24, 10, p. 694-717 24 p.

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Cannabidiol-enriched oil for adult patients with drug-resistant epilepsy: Prospective clinical and electrophysiological study

Glatt, S., Shohat, S., Yam, M., Goldstein, L., Maidan, I. & Fahoum, F., Aug 2024, In: Epilepsia. 65, 8, p. 2270-2279 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Capturing Autoinhibited PDK1 Reveals the Linker’s Regulatory Role, Informing Innovative Inhibitor Design

Xu, L., Jang, H. & Nussinov, R., 14 Oct 2024, In: Journal of Chemical Information and Modeling. 64, 19, p. 7709-7724 16 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

CDK2 and CDK4: Cell Cycle Functions Evolve Distinct, Catalysis-Competent Conformations, Offering Drug Targets

Zhang, W., Liu, Y., Jang, H. & Nussinov, R., 27 May 2024, In: JACS Au. 4, 5, p. 1911-1927 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Chromosome 7 Gain Compensates for Chromosome 10 Loss in Glioma

Nair, N. U., Schäffer, A. A., Michael Gertz, E., Cheng, K., Zerbib, J., Sahu, A. D., Leor, G., Shulman, E. D., Aldape, K. D., Ben-David, U. & Ruppin, E., 15 Oct 2024, In: Cancer Research. 84, 20, p. 3464-3477 14 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

CKAP5 stabilizes CENP-E at kinetochores by regulating microtubule-chromosome attachments

Lakshmi, R. B., Nayak, P., Raz, L., Sarkar, A., Saroha, A., Kumari, P., Nair, V. M., Kombarakkaran, D. P., Sajana, S., Sanusha, M. G., Agasti, S. S., Paul, R., Ben-David, U. & Manna, T. K., 12 Apr 2024, In: EMBO Reports. 25, 4, p. 1909-1935 27 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Crosslinking of Ly6a metabolically reprograms CD8 T cells for cancer immunotherapy

Maliah, A., Santana-Magal, N., Parikh, S., Gordon, S., Reshef, K., Sade, Y., Khateeb, A., Richter, A., Gutwillig, A., Parikh, R., Golan, T., Krissi, M., Na, M., Binshtok, G., Manich, P., Elkoshi, N., Grisaru-Tal, S., Zemser-Werner, V., Brenner, R. & Vaknine, H. & 12 others, Nizri, E., Moyal, L., Amitay-Laish, I., Rosemberg, L., Munitz, A., Kronfeld-Schor, N., Shifrut, E., Kobiler, O., Madi, A., Geiger, T., Carmi, Y. & Levy, C., Dec 2024, In: Nature Communications. 15, 1, 8354.

Research output: Contribution to journal › Article › peer-review

Open Access

Davunetide sex-dependently boosts memory in prodromal Alzheimer's disease

Gozes, I., Blatt, J. & Lobyntseva, A., 2 Oct 2024, In: Translational Psychiatry. 14, 1, p. 412 1 p.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

Disruption of Ca²⁺/calmodulin:KSR1 interaction lowers ERK activation

Thines, L., Jang, H., Li, Z., Sayedyahossein, S., Maloney, R., Nussinov, R. & Sacks, D. B., May 2024, In: Protein Science. 33, 5, e4982.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Efficacy of therapy by MK-28 PERK activation in the Huntington's disease R6/2 mouse model

Shacham, T., Offen, D. & Lederkremer, G. Z., Mar 2024, In: Neurotherapeutics. 21, 2, e00335.

Research output: Contribution to journal › Article › peer-review

Open Access

Extended phenotypic characterization of a novel Helsmoortel-van der Aa syndrome case series

Pascolini, G., Di Zenzo, G., Panebianco, A., Didona, B. & Gozes, I., May 2024, In: American Journal of Medical Genetics, Part A. 194, 5, e63539.

Research output: Contribution to journal › Article › peer-review

Open Access

Feeder-free culture of human pluripotent stem cells drives MDM4-mediated gain of chromosome 1q

Stavish, D., Price, C. J., Gelezauskaite, G., Alsehli, H., Leonhard, K. A., Taapken, S. M., McIntire, E. M., Laing, O., James, B. M., Riley, J. J., Zerbib, J., Baker, D., Harding, A. L., Jestice, L. H., Eleveld, T. F., Gillis, A. J. M., Hillenius, S., Looijenga, L. H. J., Gokhale, P. J. & Ben-David, U. & 2 others, Ludwig, T. E. & Barbaric, I., 13 Aug 2024, In: Stem Cell Reports. 19, 8, p. 1217-1232 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Gilteritinib with or without venetoclax for relapsed/refractory FLT3-mutated acute myeloid leukaemia

Kugler, E., Cohen, I., Amitai, I., Ram, R., Frisch, A., Nachmias, B., Canaani, J., Moshe, Y., Krayem, B., Aumann, S., Henig, I., Vainstein, V., Shargian, L., Ganzel, C., Yeshurun, M., Levi, I., Raanani, P., Akria, L., Ofran, Y. & Shimony, S. & 1 others, Wolach, O., Sep 2024, In: British Journal of Haematology. 205, 3, p. 932-941 10 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Human aneuploid cells depend on the RAF/MEK/ERK pathway for overcoming increased DNA damage

Zerbib, J., Ippolito, M. R., Eliezer, Y., De Feudis, G., Reuveni, E., Savir Kadmon, A., Martin, S., Viganò, S., Leor, G., Berstler, J., Muenzner, J., Mülleder, M., Campagnolo, E. M., Shulman, E. D., Chang, T., Rubolino, C., Laue, K., Cohen-Sharir, Y., Scorzoni, S. & Taglietti, S. & 9 others, Ratti, A., Stossel, C., Golan, T., Nicassio, F., Ruppin, E., Ralser, M., Vazquez, F., Ben-David, U. & Santaguida, S., Dec 2024, In: Nature Communications. 15, 1, 7772.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

IGF1R inhibition and PD-1 blockade improve anti-tumor immune response in epithelial ovarian cancer

Somri-Gannam, L., Meisel-Sharon, S., Hantisteanu, S., Bar-Noy, T., Sigal, E., Groisman, G., Hallak, M., Werner, H. & Bruchim, I., 2024, In: Frontiers in Oncology. 14, 1410447.

Research output: Contribution to journal › Article › peer-review

Open Access

Increased RNA and Protein Degradation Is Required for Counteracting Transcriptional Burden and Proteotoxic Stress in Human Aneuploid Cells

Ippolito, M. R., Zerbib, J., Eliezer, Y., Reuveni, E., Viganò, S., De Feudis, G., Shulman, E. D., Kadmon, A. S., Slutsky, R., Chang, T., Campagnolo, E. M., Taglietti, S., Scorzoni, S., Gianotti, S., Martin, S., Muenzner, J., Mülleder, M., Rozenblum, N., Rubolino, C. & Ben-Yishay, T. & 9 others, Laue, K., Cohen-Sharir, Y., Vigorito, I., Nicassio, F., Ruppin, E., Ralser, M., Vazquez, F., Santaguida, S. & Ben-David, U., 1 Dec 2024, In: Cancer Discovery. 14, 12, p. 2532-2553 22 p.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

Human Molecular Genetics Biochemistry

Research output

Search results