Human Molecular Genetics Biochemistry

2024

Characterizing Rare Dormant and Cycling Lineages Using the Watermelon System

Handly-Santana, A. & Oren, Y., 2024, Methods in Molecular Biology. Humana Press Inc., p. 165-175 11 p. (Methods in Molecular Biology; vol. 2811).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

2021

Activity-dependent neuroprotective protein (ADNP)-end-binding protein (EB) interactions regulate microtubule dynamics toward protection against tauopathy

Ivashko-Pachima, Y. & Gozes, I., Jan 2021, Molecular Biology of Neurodegenerative Diseases: Visions for the Future, Part B. Teplow, D. B. (ed.). Elsevier B.V., p. 65-90 26 p. (Progress in Molecular Biology and Translational Science; vol. 177).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

14 Scopus citations

The Allosteric Effect in Antibody-Antigen Recognition

Zhao, J., Nussinov, R. & Ma, B., 2021, Methods in Molecular Biology. Humana Press Inc., p. 175-183 9 p. (Methods in Molecular Biology; vol. 2253).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Open Access

4 Scopus citations

2020

Activity-dependent neuroprotective protein (ADNP)/NAP (CP201): Autism, schizophrenia, and Alzheimer’s disease

Gozes, I., 1 Jan 2020, Neuroprotection in Autism, Schizophrenia and Alzheimer's Disease. Elsevier, p. 3-20 18 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Perinatal lipid nutrition

Leikin-Frenkel, A. I., 1 Jan 2020, Molecular Nutrition: Mother and Infant. Elsevier, p. 337-359 23 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

4 Scopus citations

2019

Activity-dependent neuroprotective protein (ADNP)/NAP (CP201): Autism, schizophrenia, and Alzheimer's disease

Gozes, I., 16 Oct 2019, Neuroprotection in Autism, Schizophrenia and Alzheimer's disease. Elsevier, p. 3-20 18 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

2 Scopus citations

Dynamic protein allosteric regulation and disease

Nussinov, R., Tsai, C. J. & Jang, H., 2019, Advances in Experimental Medicine and Biology. Springer, p. 25-43 19 p. (Advances in Experimental Medicine and Biology; vol. 1163).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

16 Scopus citations

Interface-Based Structural Prediction of Novel Host-Pathogen Interactions

Guven-Maiorov, E., Tsai, C. J., Ma, B. & Nussinov, R., 2019, Methods in Molecular Biology. Humana Press Inc., p. 317-335 19 p. (Methods in Molecular Biology; vol. 1851).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Open Access

16 Scopus citations

Methods for Discovering and Targeting Druggable Protein-Protein Interfaces and Their Application to Repurposing

Ozdemir, E. S., Halakou, F., Nussinov, R., Gursoy, A. & Keskin, O., 2019, Methods in Molecular Biology. Humana Press Inc., p. 1-21 21 p. (Methods in Molecular Biology; vol. 1903).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Open Access

27 Scopus citations

2018

Experimental and computational protocols for studies of cross-seeding amyloid assemblies

Ren, B., Hu, R., Zhang, M., Liu, Y., Xu, L., Jiang, B., Ma, J., Ma, B., Nussinov, R. & Zheng, J., 2018, Methods in Molecular Biology. Humana Press Inc., p. 429-447 19 p. (Methods in Molecular Biology; vol. 1777).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Open Access

12 Scopus citations

Replica exchange molecular dynamics: A practical application protocol with solutions to common problems and a peptide aggregation and self-assembly example

Qi, R., Wei, G., Ma, B. & Nussinov, R., 2018, Methods in Molecular Biology. Humana Press Inc., p. 101-119 19 p. (Methods in Molecular Biology; vol. 1777).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Open Access

77 Scopus citations

2017

A protocol for the design of protein and peptide nanostructure self-assemblies exploiting synthetic amino acids

Haspel, N., Zheng, J., Aleman, C., Zanuy, D. & Nussinov, R., 2017, Methods in Molecular Biology. Humana Press Inc., p. 323-352 30 p. (Methods in Molecular Biology; vol. 1529).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Open Access

Computational tools for allosteric drug discovery: Site identification and focus library design

Huang, W., Nussinov, R. & Zhang, J., 2017, Methods in Molecular Biology. Humana Press Inc., p. 439-446 8 p. (Methods in Molecular Biology; vol. 1529).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Open Access

18 Scopus citations

Introduction

Gozes, I., 20 Jan 2017, Neuroprotection in Alzheimer's Disease. Elsevier Inc., p. 1-2 2 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Monitoring the ATM-mediated DNA damage response in the cerebellum using organotypic cultures

Tal, E. & Shiloh, Y., 2017, Methods in Molecular Biology. Humana Press Inc., p. 419-430 12 p. (Methods in Molecular Biology; vol. 1599).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

1 Scopus citations

Neuroprotective Drug Development: The Story of ADNP, NAP (Davunetide), and SKIP

Gozes, I., 20 Jan 2017, Neuroprotection in Alzheimer's Disease. Elsevier Inc., p. 253-270 18 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

6 Scopus citations

Plasma biomarker identification and quantification by microparticle proteomics

Harel, M. & Geiger, T., 2017, Methods in Molecular Biology. Humana Press Inc., p. 477-486 10 p. (Methods in Molecular Biology; vol. 1619).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

2 Scopus citations

Prediction of protein interactions by structural matching: Prediction of PPI networks and the effects of mutations on PPIs that combines sequence and structural information

Tuncbag, N., Keskin, O., Nussinov, R. & Gursoy, A., 2017, Methods in Molecular Biology. Humana Press Inc., p. 255-270 16 p. (Methods in Molecular Biology; vol. 1558).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Open Access

5 Scopus citations

Probing oligomerized conformations of defensin in the membrane

Gan, W., Schneidman, D., Zhang, N., Ma, B. & Nussinov, R., 2017, Methods in Molecular Biology. Humana Press Inc., p. 353-362 10 p. (Methods in Molecular Biology; vol. 1529).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Open Access

4 Scopus citations

RGS2 and SIRT1 Link Renin Angiotensin Aldosterone System to Alzheimer's Disease

Hadar, A., Gozes, I. & Gurwitz, D., 20 Jan 2017, Neuroprotection in Alzheimer's Disease. Elsevier Inc., p. 239-251 13 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

4 Scopus citations

The Slc26a4^loop mouse model for Pendred's syndrome and nonsyndromic deafness

Dror, A. A. & Avraham, K. B., 2 Mar 2017, The Role of Pendrin in Health and Disease: Molecular and Functional Aspects of the SLC26A4 Anion Exchanger. Springer International Publishing, p. 23-36 14 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

1 Scopus citations

2016

Computational methods for structural and functional studies of alzheimer’s amyloid ion channels

Jang, H., Teran Arce, F., Lee, J., Gillman, A. L., Ramachandran, S., Kagan, B. L., Lal, R. & Nussinov, R., 2016, Methods in Molecular Biology. Humana Press Inc., p. 251-268 18 p. (Methods in Molecular Biology; vol. 1345).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

5 Scopus citations

2015

Genomic Applications in Audiological Medicine

Karfunkel-Doron, D., Brownstein, Z. & Avraham, K. B., 1 Feb 2015, Genomic MedicinePrinciples and Practice. Oxford, UK: Oxford University Press

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

The ATM-mediated DNA-damage response

Shiloh, Y., 1 Jan 2015, Molecular Oncology: Causes of Cancer and Targets for Treatment. Cambridge University Press, p. 403-422 20 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

The INSR/IGF1R receptor family

Sarfstein, R. & Werner, H., 1 Jan 2015, Receptor Tyrosine Kinases: Family and Subfamilies. Springer International Publishing, p. 297-320 24 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

6 Scopus citations

2014

Design and application of super-SILAC for proteome quantification

Pozniak, Y. & Geiger, T., 2014, Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC): Methods and Protocols. Humana Press Inc., p. 281-291 11 p. (Methods in Molecular Biology; vol. 1188).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

10 Scopus citations

Human Gene Discovery for Understanding Development of the Inner Ear and Hearing Loss

Bhonker, Y., Ushakov, K. & Avraham, K. B., 2 Jun 2014, Development of Auditory and Vestibular Systems: Fourth Edition. Elsevier Inc., p. 107-127 21 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

2 Scopus citations

Stem Cells as a Source for Cell Therapy in Parkinson's Disease

Lescaudron, L. (Editor), Rossignol, J. (Editor), Dunbar, G. (Editor), Offen, D., Lev, N. & Ganz, J., 1 Mar 2014, Stem Cells and Neurodegenerative Diseases. CRC Press, 19 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

The NOTCH pathway in β-cell growth and differentiation

Bar, Y. & Efrat, S., 2014, Vitamins and Hormones. Academic Press Inc., p. 391-405 15 p. (Vitamins and Hormones; vol. 95).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

11 Scopus citations

2013

Activity-dependent neuroprotective protein (adnp) and davunetide (nap)

Gozes, I. & Baas, P. W., 2013, Handbook of Biologically Active Peptides. Elsevier Inc., p. 1611-1618 8 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

2 Scopus citations

Deafness gene discovery in the genomic era

Elkan-Miller, T. & Avraham, K. B., Jan 2013, Inner Ear Development and Hearing Loss. Nova Science Publishers, Inc., p. 127-142 16 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Molecular Etiology of Deafness and Cochlear Consequences

Brownstein, Z., Shivatzki, S. & Avraham, K. B., 2013, DEAFNESS. Vol. 47. p. 17-39 (Springer Handbook of Auditory Research).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Principles of Shape-Driven Nanostructure Design via Self-Assembly of Protein Building Blocks

Buch, I., Tsai, C. J., Alemán, C. & Nussinov, R., 27 Mar 2013, Peptide Materials: From Nanostructures to Applications. John Wiley and Sons, p. 171-189 19 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Recent Advances in ALS Research: Perspectives for Personalized Clinical Application

Benkler, C., Offen, D., Melamed, E., Amit, T., Mandel, S., Youdim, M. B. H. & Weinreb, O., 2013, New Strategies to Advance Pre/Diabetes Care: Integrative Approach by PPPM. Kluwer Academic Publishers, p. 235-274 40 p. (Advances in Predictive, Preventive and Personalised Medicine; vol. 3).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Structured crowding and its effects on enzyme catalysis

Ma, B. & Nussinov, R., 2013, Dynamics in Enzyme Catalysis. Klinman, J. & Hammes-Schiffer, S. (eds.). p. 123-138 16 p. (Topics in Current Chemistry; vol. 337).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Open Access

34 Scopus citations

Structure-Function Studies of Amyloid Pores in Alzheimer's Disease as a Case Example of Neurodegenerative Diseases

Arce, F. T., Jang, H., Connelly, L., Ramachandran, S., Kagan, B. L., Nussinov, R. & Lal, R., Nov 2013, Bio-nanoimaging: Protein Misfolding and Aggregation. Elsevier Inc., p. 397-408 12 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

1 Scopus citations

Tau Pathology: A Selected View on the Current Status

Gozes, I., 2013, New Strategies to Advance Pre/Diabetes Care: Integrative Approach by PPPM. Kluwer Academic Publishers, p. 69-92 24 p. (Advances in Predictive, Preventive and Personalised Medicine; vol. 3).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

The cytoskeleton as a pharmacological target in neurodegenerative diseases

Oz, S. & Gozes, I., 2013, The Cytoskeleton: Imaging, Isolation, and Interaction. Humana Press Inc., p. 151-169 19 p. (Neuromethods; vol. 79).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

2012

Analyzing the genomic integrity of stem cells

Ben-David, U. & Benvenisty, N., 10 Jun 2012, Stembook. The Stem Cell Research Community

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Cancer genes, tumor suppressors, and regulation of IGF1-R gene expression in cancer

Werner, H., Attias-Geva, Z., Bentov, I., Sarfstein, R., Schayek, H., Weinstein, D. & Bruchim, I., 1 Jan 2012, Insulin-like Growth Factors and Cancer: From Basic Biology to Therapeutics. Springer US, p. 159-177 19 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

1 Scopus citations

Expanding the conformational selection paradigm in protein-ligand docking

Kuzu, G., Keskin, O., Gursoy, A. & Nussinov, R., 2012, Computational Drug Discovery and Design. Baron, R. (ed.). p. 59-74 16 p. (Methods in Molecular Biology; vol. 819).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Open Access

10 Scopus citations

MicroRNAs in the inner ear: Implications for hearing loss

Friedman, L. M., Elkan-Miller, T., Rudnicki, A., Dror, A. A. & Avraham, K. B., 2012, Usher Syndrome: Pathogenesis, Diagnosis and Therapy. Nova Science Publishers, Inc., p. 179-197 19 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

2011

In-Vivo Functional Assessment of Engineered Human Insulin-Producing Cells

Russ, H. A. & Efrat, S., 2011, METHODS IN BIOENGINEERING: CELL TRANSPLANTATION. p. 35-46 (Artech House Methods in Bioengineering Series).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

2010

Beta-Cell Expansion in Vitro

Efrat, S., 2010, Stem Cell Therapy for Diabetes. Efrat, S. (ed.). New York: Humana Press, p. 123-133 (Stem Cell Biology and Regenerative Medicine).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

2008

Prism: Protein-protein interaction prediction by structural matching

Keskin, O., Nussinov, R. & Gursoy, A., 2008, Functional Proteomics: Methods and Protocols. Thompson, J. D., Ueffing, M. & Schaeffer-Reiss, C. (eds.). p. 505-521 17 p. (Methods in Molecular Biology; vol. 484).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Open Access

66 Scopus citations

Self-assembly of fused homo-oligomers to create nanotubes

Buch, I., Tsai, C. J., Wolfson, H. J. & Nussinov, R., 2008, Nanostructure Design: Methods and Protocols. Humana Press, p. 117-131 15 p. (Methods in Molecular Biology; vol. 474).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

1 Scopus citations

What can we learn from highly connected β-rich structures for structural interface design?

Emekli, U., Gunasekaran, K., Nussinov, R. & Haliloglu, T., 2008, Nanostructure Design: Methods and Protocols. Gazit, E., Nussinov, R. & Nussinov, R. (eds.). p. 235-253 19 p. (Methods in Molecular Biology; vol. 474).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

2 Scopus citations

2007

Algorithms for multiple protein structure alignment and structure-derived multiple sequence alignment

Shatsky, M., Nussinov, R. & Wolfson, H. J., 5 Oct 2007, Protein Structure Prediction, Second Edition. Humana Press, p. 125-146 22 p. (Methods in Molecular Biology; vol. 413).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

3 Scopus citations

Autotransplantation of bone marrow-derived stem cells as a therapy for neurodegenerative diseases

Kan, I., Melamed, E. & Offen, D., 2007, Bone Marrow-Derived Progenitors. Springer Science and Business Media, LLC, p. 219-242 24 p. (Handbook of Experimental Pharmacology; vol. 180).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

61 Scopus citations

Engineered cells for treatment of diabetes

Efrat, S., May 2007, Artificial Cells, Cell Engineering and Therapy. Elsevier Inc., p. 388-403 16 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Human Molecular Genetics Biochemistry

Research output

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