Human Molecular Genetics Biochemistry

Research output

Research output per year 1962 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2022

• 165230 Citations
• 171 h-index
• 2131 Article
• 357 Review article
• 84 Comment/debate
• 73 Editorial
• 177 More
  • 65 Chapter
  • 40 Letter
  • 34 Short survey
  • 15 Meeting Abstract
  • 12 Conference contribution
  • 6 Book
  • 3 Foreword/postscript
  • 2 Conference article

Research output per year

Research output per year

Search results

• 2019

  ClinGen expert clinical validity curation of 164 hearing loss gene–disease pairs

  on behalf of the ClinGen Hearing Loss Clinical Domain Working Group, 1 Oct 2019, In: Genetics in Medicine. 21, 10, p. 2239-2247 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Hearing Loss 100%
  • Genome 71%
  • Genetic Testing 46%
  • Genes 42%
  • Clinical Decision-Making 15%

• Clinical Presentation of a Complex Neurodevelopmental Disorder Caused by Mutations in ADNP

  ADNP Consortium, 15 Feb 2019, In: Biological Psychiatry. 85, 4, p. 287-297 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Neurodevelopmental Disorders 100%
  • Mutation 47%
  • Autistic Disorder 42%
  • Intellectual Disability 40%
  • Genetic Association Studies 22%

• Combinatorial treatment increases IKAP levels in human cells generated from Familial Dysautonomia patients

  Yannai, S., Zonszain, J., Donyo, M. & Ast, G., Mar 2019, In: PLoS ONE. 14, 3, e0211602.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Familial Dysautonomia 100%
  • pridopidine 82%
  • Phosphatidylserines 69%
  • Kinetin 37%
  • trichostatin A 26%

• Combined treatment with 9-cis β-carotene and 22R-hydroxycholesterol augments cholesterol efflux in macrophages

  Mahler, L., Harari, A., Harats, D., Ben-Amotz, A., Peled, M., Leikin-Frenkel, A., Kandel Kfir, M., Kamari, Y. & Shaish, A., Dec 2019, In: Algal Research. 44, 101700.

  Research output: Contribution to journal › Article › peer-review

  • hydroxycholesterols 100%
  • carotenes 73%
  • macrophages 59%
  • cholesterol 50%
  • receptors 31%

• Computational structural biology: Successes, future directions, and challenges

  Nussinov, R., Tsai, C. J., Shehu, A. & Jang, H., 12 Feb 2019, In: Molecules. 24, 3, 637.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • biology 100%
  • Computational Biology 88%
  • Sampling 77%
  • Direction compound 68%
  • data integration 41%

• Conformational stability and dynamics of the cancer-associated isoform Δ133p53β are modulated by p53 peptides and p53-specific DNA

  Lei, J., Qi, R., Tang, Y., Wang, W., Wei, G., Nussinov, R. & Ma, B., 1 Mar 2019, In: FASEB Journal. 33, 3, p. 4225-4235 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Protein Isoforms 100%
  • Peptides 79%
  • Peptide 71%
  • DNA 69%
  • Tumor Suppressor Protein 65%

• Consensus interpretation of the p.Met34Thr and p.Val37Ile variants in GJB2 by the ClinGen Hearing Loss Expert Panel

  on behalf of the ClinGen Hearing Loss Working Group, 1 Nov 2019, In: Genetics in Medicine. 21, 11, p. 2442-2452 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Hearing Loss 100%
  • Nonsyndromic Deafness 53%
  • Guidelines 45%
  • Population Control 41%
  • Penetrance 40%

• Considerations for the use of Cre recombinase for conditional gene deletion in the mouse lens

  Lam, P. T., Padula, S. L., Hoang, T. V., Poth, J. E., Liu, L., Liang, C., LeFever, A. S., Wallace, L. M., Ashery-Padan, R., Riggs, P. K., Shields, J. E., Shaham, O., Rowan, S., Brown, N. L., Glaser, T. & Robinson, M. L., 15 Feb 2019, In: Human Genomics. 13, 1, p. 10 1 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cre recombinase 100%
  • Ocular 94%
  • Gene Deletion 80%
  • Lenses 69%
  • Transgenes 37%

• Correction: Review: Precision medicine and driver mutations: Computational methods, functional assays and conformational principles for interpreting cancer drivers (PLoS Comput Biol, (2019), 15, 3, 10.1371/journal.pcbi.1006658)

  Nussinov, R., Jang, H., Tsai, C. J. & Cheng, F., Jun 2019, In: PLoS Computational Biology. 15, 6, e1007114.

  Research output: Contribution to journal › Comment/debate

  Open Access

  • precision medicine 100%
  • Personalized medicine 88%
  • computational methodology 81%
  • Driver 79%
  • Assays 71%

• Correction: ClinGen expert clinical validity curation of 164 hearing loss gene–disease pairs (Genetics in Medicine, (2019), 21, 10, (2239-2247), 10.1038/s41436-019-0487-0)

  on behalf of the ClinGen Hearing Loss Clinical Domain Working Group, 1 Oct 2019, In: Genetics in Medicine. 21, 10, p. 2409 1 p.

  Research output: Contribution to journal › Comment/debate

  Open Access

  • Tokyo 100%
  • Hearing Loss 80%
  • Medicine 61%
  • Japan 39%
  • Medical Genetics 32%

• DeepDR: A network-based deep learning approach to in silico drug repositioning

  Zeng, X., Zhu, S., Liu, X., Zhou, Y., Nussinov, R. & Cheng, F., 15 Dec 2019, In: Bioinformatics. 35, 24, p. 5191-5198 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Deep Learning 100%
  • Drug Repositioning 99%
  • Drugs 74%
  • Computer Simulation 68%
  • Learning 65%

• Developmental Phenotype of the Rare Case of DJ Caused by a Unique ADNP Gene De Novo Mutation

  Levine, J., Cohen, D., Herman, C., Verloes, A., Guinchat, V., Diaz, L., Cravero, C., Mandel, A. & Gozes, I., 15 Jul 2019, In: Journal of Molecular Neuroscience. 68, 3, p. 321-330 10 p.

  Research output: Contribution to journal › Editorial

  Open Access

• Developments in integrative modeling with dynamical interfaces

  Ozdemir, E. S., Nussinov, R., Gursoy, A. & Keskin, O., Jun 2019, In: Current Opinion in Structural Biology. 56, p. 11-17 7 p.

  Research output: Contribution to journal › Review article › peer-review

  • Proteins 100%

• Differential Effects of Insulin and IGF1 Receptors on ERK and AKT Subcellular Distribution in Breast Cancer Cells

  Sarfstein, R., Nagaraj, K., LeRoith, D. & Werner, H., 23 Nov 2019, In: Cells. 8, 12, 1499.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Somatomedin Receptors 100%
  • Insulin Receptor 85%
  • Insulin Derivative 77%
  • Somatomedins 64%
  • Insulin 51%

• DNA methylation directs microRNA biogenesis in mammalian cells

  Glaich, O., Parikh, S., Bell, R. E., Mekahel, K., Donyo, M., Leader, Y., Shayevitch, R., Sheinboim, D., Yannai, S., Hollander, D., Melamed, Z., Lev-Maor, G., Ast, G. & Levy, C., 1 Dec 2019, In: Nature Communications. 10, 1, 5657.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • methylation 100%
  • biological evolution 96%
  • MicroRNA 77%
  • loci 70%
  • Mammalian Cell 65%

• Does Ras Activate Raf and PI3K Allosterically?

  Nussinov, R., Tsai, C. J. & Jang, H., 15 Nov 2019, In: Frontiers in Oncology. 9, 1231.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Phosphatidylinositol 3-Kinases 100%
  • Catalytic Domain 26%
  • Membranes 17%
  • Mitogen-Activated Protein Kinase Kinases 15%
  • Pharmacology 9%

• Does SCFD1 rs10139154 Polymorphism Decrease Alzheimer’s Disease Risk?

  Stamati, P., Siokas, V., Aloizou, A. M., Karampinis, E., Arseniou, S., Rakitskii, V. N., Tsatsakis, A., Spandidos, D. A., Gozes, I., Mitsias, P. D., Bogdanos, D. P., Hadjigeorgiou, G. M. & Dardiotis, E., 1 Oct 2019, In: Journal of Molecular Neuroscience. 69, 2, p. 343-350 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Protein Domains 100%
  • Alzheimer Disease 76%
  • Disease Susceptibility 18%
  • Amyotrophic Lateral Sclerosis 17%
  • Regression Analysis 10%

• Dynamic protein allosteric regulation and disease

  Nussinov, R., Tsai, C. J. & Jang, H., 2019, Advances in Experimental Medicine and Biology. Springer, p. 25-43 19 p. (Advances in Experimental Medicine and Biology; vol. 1163).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Allosteric Regulation 100%
  • Conformational Transition 37%
  • Protein 27%
  • Proteins 24%

• Educating the Next Generation of Pharmacogenomics Experts: Global Educational Needs and Concepts

  Just, K. S., Turner, R. M., Dolžan, V., Cecchin, E., Swen, J. J., Gurwitz, D. & Stingl, JC., Aug 2019, In: Clinical Pharmacology and Therapeutics. 106, 2, p. 313-316 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Emerging Allosteric Mechanism of EGFR Activation in Physiological and Pathological Contexts

  Tsai, C. J. & Nussinov, R., 9 Jul 2019, In: Biophysical Journal. 117, 1, p. 5-13 9 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • ErbB Receptors 100%
  • Dimerization 89%
  • Ligands 74%
  • Phosphotransferases 40%
  • Protein Kinases 24%

• Genetic Therapies for Hearing Loss: Accomplishments and Remaining Challenges

  Taiber, S. & Avraham, K. B., 20 Nov 2019, In: Neuroscience Letters. 713, 134527.

  Research output: Contribution to journal › Review article › peer-review

  • Hearing Loss 100%
  • Genetic Therapy 97%
  • Human Genome Project 48%
  • Optimism 42%
  • Hope 40%

• Genome-wide profiling of Laron syndrome patients identifies novel cancer protection pathways

  Werner, H., Lapkina-Gendler, L., Achlaug, L., Nagaraj, K., Somri, L., Yaron-Saminsky, D., Pasmanik-Chor, M., Sarfstein, R., Laron, Z. & Yakar, S., 2019, In: Cells. 8, 6, 596.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Laron Syndrome 100%
  • Somatomedins 65%
  • Genome 41%
  • Neoplasms 19%
  • Growth Hormone 19%

• Genome-Wide Profiling of Laron Syndrome Patients Identifies Novel Cancer Protection Pathways

  Werner, H., Lapkina-Gendler, L., Achlaug, L., Nagaraj, K., Somri, L., Yaron-Saminsky, D., Pasmanik-Chor, M., Sarfstein, R., Laron, Z. & Yakar, S., 15 Jun 2019, In: Cells. 8, 6

  Research output: Contribution to journal › Review article › peer-review

  • Laron Syndrome 100%
  • Somatomedins 65%
  • Genome 41%
  • Neoplasms 19%
  • Growth Hormone 19%

• Genomics and the future of psychopharmacology: MicroRNAs offer novel therapeutics

  Gurwitz, D., 2019, In: Dialogues in Clinical Neuroscience. 21, 2, p. 131-138 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Psychopharmacology 100%
  • Genomics 73%
  • MicroRNAs 61%
  • Small Untranslated RNA 14%
  • X Chromosome 13%

• GIP regulates inflammation and body weight by restraining myeloid-cell-derived S100A8/A9

  Mantelmacher, F. D., Zvibel, I., Cohen, K., Epshtein, A., Pasmanik-Chor, M., Vogl, T., Kuperman, Y., Weiss, S., Drucker, D. J., Varol, C. & Fishman, S., 1 Jan 2019, In: Nature Metabolism. 1, 1, p. 58-69 12 p.

  Research output: Contribution to journal › Article › peer-review

  • gastric inhibitory polypeptide receptor 100%
  • Myeloid Cells 61%
  • Body Weight 42%
  • Nutrients 38%
  • Peptides 38%

• Golden Exosomes Selectively Target Brain Pathologies in Neurodegenerative and Neurodevelopmental Disorders

  Perets, N., Betzer, O., Shapira, R., Brenstein, S., Angel, A., Sadan, T., Ashery, U., Popovtzer, R. & Offen, D., 12 Jun 2019, In: Nano Letters. 19, 6, p. 3422-3431 10 p.

  Research output: Contribution to journal › Article › peer-review

  • pathology 100%
  • Pathology 94%
  • Clearance 89%
  • homing 80%
  • brain 78%

• Histone H1.5 binds over splice sites in chromatin and regulates alternative splicing

  Glaich, O., Leader, Y., Lev Maor, G. & Ast, G., 8 Jul 2019, In: Nucleic Acids Research. 47, 12, p. 6145-6159 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Alternative Splicing 100%
  • Histones 86%
  • Chromatin 81%
  • Exons 76%
  • RNA Polymerase II 35%

• Human muscle progenitor cells overexpressing neurotrophic factors improve neuronal regeneration in a sciatic nerve injury mouse model

  Guy, R., Grynspan, F., Ben-Zur, T., Panski, A., Lamdan, R., Danon, U., Yaffe, D. & Offen, D., 2019, In: Frontiers in Neuroscience. 13, FEB, 151.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Nerve Growth Factors 100%
  • Sciatic Nerve 98%
  • Muscle Cells 85%
  • Regeneration 77%
  • Stem Cells 68%

• Identification of nucleolar protein NOM1 as a novel nuclear IGF1R-interacting protein

  Solomon-Zemler, R., Pozniak, Y., Geiger, T. & Werner, H., Mar 2019, In: Molecular Genetics and Metabolism. 126, 3, p. 259-265 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Receptor-Interacting Protein Serine-Threonine Kinases 100%
  • Somatomedin Receptors 93%
  • Nuclear Proteins 73%
  • Protein 29%
  • Eukaryotic Initiation Factor-4G 13%

• Identification of ZYG11A as a candidate IGF1-dependent protooncogene in endometrial cancer

  Achlaug, L., Sarfstein, R., Nagaraj, K., Lapkina-Gendler, L., Bruchim, I., Dixit, M., Laron, Z., Yakar, S. & Werner, H., 1 Jul 2019, In: Oncotarget. 10, 43, p. 4437-4448 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Laron Syndrome 100%
  • Endometrial Neoplasms 83%
  • Insulin-Like Growth Factor I Deficiency 37%
  • Somatotropin Receptors 28%
  • Dwarfism 28%

• Interface-Based Structural Prediction of Novel Host-Pathogen Interactions

  Guven-Maiorov, E., Tsai, C. J., Ma, B. & Nussinov, R., 2019, Methods in Molecular Biology. Humana Press Inc., p. 317-335 19 p. (Methods in Molecular Biology; vol. 1851).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Host-Pathogen Interactions 100%
  • Kaposi's Sarcoma 18%
  • Herpesviridae 17%
  • Proteins 16%
  • Neoplasms 14%

• Intranasal Delivery of Mesenchymal Stem Cell Derived Exosomes Loaded with Phosphatase and Tensin Homolog siRNA Repairs Complete Spinal Cord Injury

  Guo, S., Perets, N., Betzer, O., Ben-Shaul, S., Sheinin, A., Michaelevski, I., Popovtzer, R., Offen, D. & Levenberg, S., 24 Sep 2019, In: ACS Nano. 13, 9, p. 10015-10028 14 p.

  Research output: Contribution to journal › Article › peer-review

  • spinal cord injuries 100%
  • Phosphatases 87%
  • Intranasal 84%
  • phosphatases 77%
  • Stem cells 74%

• Introduction

  Gozes, I. & Levine, J., 16 Oct 2019, Neuroprotection in Autism, Schizophrenia and Alzheimer's disease. Elsevier, p. xiii-xviii

  Research output: Chapter in Book/Report/Conference proceeding › Foreword/postscript

• Investigational IGF1R inhibitors in early stage clinical trials for cancer therapy

  Werner, H., Sarfstein, R. & Bruchim, I., 2 Dec 2019, In: Expert Opinion on Investigational Drugs. 28, 12, p. 1101-1112 12 p.

  Research output: Contribution to journal › Review article › peer-review

  • Somatomedins 100%
  • Clinical Trials 61%
  • Neoplasms 30%
  • Peptide Hormones 28%
  • Cell Surface Receptors 25%

• In vivo, in vitro and in silico correlations of four de novo SCN1A missense mutations

  Nissenkorn, A., Almog, Y., Adler, I., Safrin, M., Brusel, M., Marom, M., Bercovich, S., Yakubovich, D., Tzadok, M., Ben-Zeev, B. & Rubinstein, M., Feb 2019, In: PLoS ONE. 14, 2, e0211901.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Missense Mutation 100%
  • Computer Simulation 91%
  • Mutation 54%
  • Seizures 44%
  • In Vitro Techniques 42%

• Is Nanoclustering essential for all oncogenic KRas pathways? Can it explain why wild-type KRas can inhibit its oncogenic variant?

  Nussinov, R., Tsai, C. J. & Jang, H., Feb 2019, In: Seminars in Cancer Biology. 54, p. 114-120 7 p.

  Research output: Contribution to journal › Review article › peer-review

  • Phosphatidylinositol 3-Kinases 100%
  • Dimerization 85%
  • Calmodulin 55%
  • Protein Isoforms 40%
  • raf Kinases 39%

• Loss-of-function mutations in caspase recruitment domain-containing protein 14 (CARD14) are associated with a severe variant of atopic dermatitis

  Peled, A., Sarig, O., Sun, G., Samuelov, L., Ma, C. A., Zhang, Y., Dimaggio, T., Nelson, C. G., Stone, K. D., Freeman, A. F., Malki, L., Vidal, L. S., Chamarthy, L. M., Briskin, V., Mohamad, J., Pavlovsky, M., Walter, J. E., Milner, J. D. & Sprecher, E., Jan 2019, In: Journal of Allergy and Clinical Immunology. 143, 1, p. 173-181.e10

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Caspase Activation and Recruitment Domain 100%
  • Loss of Function Mutation 76%
  • Atopic Dermatitis 70%
  • Psoriasis 26%
  • Keratinocytes 26%

• Methods for Discovering and Targeting Druggable Protein-Protein Interfaces and Their Application to Repurposing

  Ozdemir, E. S., Halakou, F., Nussinov, R., Gursoy, A. & Keskin, O., 2019, Methods in Molecular Biology. Humana Press Inc., p. 1-21 21 p. (Methods in Molecular Biology; vol. 1903).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Drug Repositioning 100%
  • Proteins 26%
  • Polypharmacology 24%
  • Protein Interaction Maps 18%
  • Pharmaceutical Preparations 18%

• Methods for single-cells

  de la Prida, L. M. & Gozes, I., 1 Dec 2019, In: Journal of Neuroscience Methods. 328, 108413.

  Research output: Contribution to journal › Editorial

• MicroRNAs affect complement regulator expression and mitochondrial activity to modulate cell resistance to complement-dependent cytotoxicity

  Hillman, Y., Mardamshina, M., Pasmanik-Chor, M., Ziporen, L., Geiger, T., Shomron, N. & Fishelson, Z., 2019, In: Cancer immunology research. 7, 12, p. 1970-1983 14 p.

  Research output: Contribution to journal › Article › peer-review

  • MicroRNAs 100%
  • K562 Cells 12%
  • Mitochondria 8%
  • Complement System Proteins 6%
  • Cell Shape 6%

• Microvesicle proteomic profiling of uterine liquid biopsy for ovarian cancer early detection

  Barnabas, G. D., Bahar-Shany, K., Sapoznik, S., Helpman, L., Kadan, Y., Beiner, M., Weitzner, O., Arbib, N., Korach, J., Perri, T., Katz, G., Blecher, A., Brandt, B., Friedman, E., Stockheim, D., Jakobson-Setton, A., Eitan, R., Armon, S., Brand, H., Zadok, O., & 4 othersAviel-Ronen, S., Harel, M., Geiger, T. & Levanon, K., May 2019, In: Molecular and Cellular Proteomics. 18, 5, p. 865-875 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Liquid Biopsy 100%
  • Proteomics 65%
  • Ovarian Neoplasms 65%
  • Biological Marker 64%
  • Therapeutic Irrigation 60%

• Mitochondrial Function Is Compromised in Cortical Bone Osteocytes of Long-Lived Growth Hormone Receptor Null Mice

  Liu, Z., Solesio, M. E., Schaffler, M. B., Frikha-Benayed, D., Rosen, C. J., Werner, H., Kopchick, J. J., Pavlov, E. V., Abramov, A. Y. & Yakar, S., Jan 2019, In: Journal of Bone and Mineral Research. 34, 1, p. 106-122 17 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Somatotropin Receptors 100%
  • Osteocytes 90%
  • Cortical Bone 78%
  • Mitochondrial Membrane Potential 16%
  • Longevity 14%

• Mitochondrial Regulation of the Hippocampal Firing Rate Set Point and Seizure Susceptibility

  Styr, B., Gonen, N., Zarhin, D., Ruggiero, A., Atsmon, R., Gazit, N., Braun, G., Frere, S., Vertkin, I., Shapira, I., Harel, M., Heim, L. R., Katsenelson, M., Rechnitz, O., Fadila, S., Derdikman, D., Rubinstein, M., Geiger, T., Ruppin, E. & Slutsky, I., 5 Jun 2019, In: Neuron. 102, 5, p. 1009-1024.e8

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Epilepsy 100%
  • Seizures 92%
  • Research Personnel 82%
  • Bone and Bones 70%

• Myeloperoxidase Deficiency Inhibits Cognitive Decline in the 5XFAD Mouse Model of Alzheimer’s Disease

  Volkman, R., Ben-Zur, T., Kahana, A., Garty, B. Z. & Offen, D., 24 Sep 2019, In: Frontiers in Neuroscience. 13, 990.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Myeloperoxidase Deficiency 100%
  • Peroxidase 54%
  • Cognitive Dysfunction 46%
  • Alzheimer Disease 43%
  • Neutrophils 19%

• NAP (davunetide) preferential interaction with dynamic 3-repeat Tau explains differential protection in selected tauopathies

  Ivashko-Pachima, Y., Maor-Nof, M. & Gozes, I., Mar 2019, In: PLoS ONE. 14, 3, e0213666.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • davunetide 100%
  • Tauopathies 73%
  • Microtubules 52%
  • Protein Deficiency 23%
  • Cognition 14%

• Negative regulatory loop between microphthalmia-associated transcription factor (MITF) and notch signaling

  Golan, T. & Levy, C., 1 Feb 2019, In: International Journal of Molecular Sciences. 20, 3, 576.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Microphthalmia-Associated Transcription Factor 100%
  • Transcription factors 95%
  • Plastic Property 77%
  • notches 72%
  • Melanoma 55%

• Neuroprotection in Autism, Schizophrenia and Alzheimer's disease

  Gozes, I. & Levine, J., 16 Oct 2019, Elsevier. 322 p.

  Research output: Book/Report › Book › peer-review

  • Neuroprotection 100%
  • Autistic Disorder 95%
  • Schizophrenia 77%
  • Alzheimer Disease 73%
  • Neurodevelopmental Disorders 37%

• Oncogenic KRas mobility in the membrane and signaling response

  Nussinov, R., Tsai, C. J. & Jang, H., Feb 2019, In: Seminars in Cancer Biology. 54, p. 109-113 5 p.

  Research output: Contribution to journal › Review article › peer-review

  • Phosphatidylinositol 3-Kinases 100%
  • Membranes 90%
  • Lymphocyte Specific Protein Tyrosine Kinase p56(lck) 80%
  • Reaction Time 47%
  • Cell Membrane 36%

• Oncoviruses Can Drive Cancer by Rewiring Signaling Pathways Through Interface Mimicry

  Guven-Maiorov, E., Tsai, C. J. & Nussinov, R., 15 Nov 2019, In: Frontiers in Oncology. 9, 1236.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Retroviridae 100%
  • Host Microbial Interactions 46%
  • Neoplasms 29%
  • Proteins 27%
  • Drug Design 21%

• Pathogenic Autoreactive T and B Cells Cross-React with Mimotopes Expressed by a Common Human Gut Commensal to Trigger Autoimmunity

  Ruff, W. E., Dehner, C., Kim, W. J., Pagovich, O., Aguiar, C. L., Yu, A. T., Roth, A. S., Vieira, S. M., Kriegel, C., Adeniyi, O., Mulla, M. J., Abrahams, V. M., Kwok, W. W., Nussinov, R., Erkan, D., Goodman, A. L. & Kriegel, M. A., 10 Jul 2019, In: Cell Host and Microbe. 26, 1, p. 100-113.e8

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Roseburia intestinalis 100%
  • autoimmunity 70%
  • Antiphospholipid Syndrome 60%
  • B-lymphocytes 49%
  • autoantibodies 49%