Eye Institute (Goldschleger)

2025

High-Adherence Dichoptic Treatment Versus Patching in Anisometropic and Small Angle Strabismus Amblyopia: A Randomized Controlled Trial

the CureSight Pivotal Trial Group, Jan 2025, In: American Journal of Ophthalmology. 269, p. 293-302 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

2024

A Proposal for the Use of a Fixed Low-Energy Selective Laser Trabeculoplasty for Open Angle Glaucoma

Sacks, Z., Katz, L. J., Gazzard, G., Van Tassel, S. H., Blumenthal, E. Z., Lerner, F. S., Azuara-Blanco, A., Spooner, G. J. R., Solberg, Y., Samuelson, T. & Belkin, M., 1 Jan 2024, In: Journal of Glaucoma. 33, 1, p. 1-7 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Binocular Home Treatment for Amblyopia: Gains Stable for One Year: Binocular Treatment for Amblyopia: Gains Stable for One Year

CureSight Pivotal Trial Group, Jun 2024, In: American Journal of Ophthalmology. 262, p. 199-205 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Complex biophysical changes and reduced neuronal firing in an SCN8A variant associated with developmental delay and epilepsy

Quinn, S., Zhang, N., Fenton, T. A., Brusel, M., Muruganandam, P., Peleg, Y., Giladi, M., Haitin, Y., Lerche, H., Bassan, H., Liu, Y., Ben-Shalom, R. & Rubinstein, M., Jun 2024, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1870, 5, 167127.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

First-in-human Clinical Trial of a Novel Eyelid Warming Device in Meibomian Gland Dysfunction

Arazi, M., Lemanski, M., Belkin, M. & Landau-Prat, D., Jan 2024, In: Israel Medical Association Journal. 26, 1, p. 45-48 4 p.

Research output: Contribution to journal › Article › peer-review

S-Allylmercapto-N-Acetylcysteine (ASSNAC) Attenuates Osteoporosis in Ovariectomized (OVX) Mice

Bleichman, I., Hiram-Bab, S., Gabet, Y. & Savion, N., Apr 2024, In: Antioxidants. 13, 4, 474.

Research output: Contribution to journal › Article › peer-review

Open Access

2023

Acute effect of antiseizure drugs on background oscillations in Scn1a ^A1783V Dravet syndrome mouse model

Quinn, S., Brusel, M., Ovadia, M. & Rubinstein, M., 2023, In: Frontiers in Pharmacology. 14, 1118216.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

An Eye-Tracking–Based Dichoptic Home Treatment for Amblyopia: A Multicenter Randomized Clinical Trial

the CureSight Pivotal Trial Group, Mar 2023, In: Ophthalmology. 130, 3, p. 274-285 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

24 Scopus citations

Heat-induced seizures, premature mortality, and hyperactivity in a novel Scn1a nonsense model for Dravet syndrome

Mavashov, A., Brusel, M., Liu, J., Woytowicz, V., Bae, H., Chen, Y. H., Dani, V. S., Cardenal-Muñoz, E., Spinosa, V., Aibar, J. Á. & Rubinstein, M., 2023, In: Frontiers in Cellular Neuroscience. 17, 1149391.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Preferential expression of SCN1A in GABAergic neurons improves survival and epileptic phenotype in a mouse model of Dravet syndrome

Ricobaraza, A., Bunuales, M., Gonzalez-Aparicio, M., Fadila, S., Rubinstein, M., Vides-Urrestarazu, I., Banderas, J., Sola-Sevilla, N., Sanchez-Carpintero, R., Lanciego, J. L., Roda, E., Honrubia, A., Arnaiz, P. & Hernandez-Alcoceba, R., Dec 2023, In: Journal of Molecular Medicine. 101, 12, p. 1587-1601 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Viral vector–mediated expression of Na_V1.1, after seizure onset, reduces epilepsy in mice with Dravet syndrome

Fadila, S., Beucher, B., Dopeso-Reyes, I. G., Mavashov, A., Brusel, M., Anderson, K., Ismeurt, C., Goldberg, E. M., Ricobaraza, A., Hernandez-Alcoceba, R., Kremer, E. J. & Rubinstein, M., 15 Jun 2023, In: Journal of Clinical Investigation. 133, 12, e159316.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

2022

Energy Dose-Response in Selective Laser Trabeculoplasty: A Review

Radcliffe, N., Gazzard, G., Samuelson, T., Khaw, P., Sun, X., Aung, T., Lam, D., Singh, K., Katz, L. J., Aronov, M., Sacks, Z., Solberg, Y., Lindstrom, R. & Belkin, M., 1 Aug 2022, In: Journal of Glaucoma. 31, 8, p. E49-E68

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

Functional Investigation of a Neuronal Microcircuit in the CA1 Area of the Hippocampus Reveals Synaptic Dysfunction in Dravet Syndrome Mice

Almog, Y., Mavashov, A., Brusel, M. & Rubinstein, M., 16 Mar 2022, In: Frontiers in Molecular Neuroscience. 15, 823640.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

Grand Challenges in global eye health: a global prioritisation process using Delphi method

Grand Challenges in Global Eye Health study group, Jan 2022, In: The Lancet Healthy Longevity. 3, 1, p. e31-e41

Research output: Contribution to journal › Article › peer-review

Open Access

32 Scopus citations

Novel ADNP Syndrome Mice Reveal Dramatic Sex-Specific Peripheral Gene Expression With Brain Synaptic and Tau Pathologies

Karmon, G., Sragovich, S., Hacohen-Kleiman, G., Ben-Horin-Hazak, I., Kasparek, P., Schuster, B., Sedlacek, R., Pasmanik-Chor, M., Theotokis, P., Touloumi, O., Zoidou, S., Huang, L., Wu, P. Y., Shi, R., Kapitansky, O., Lobyntseva, A., Giladi, E., Shapira, G., Shomron, N. & Bereswill, S. & 5 others, Heimesaat, M. M., Grigoriadis, N., McKinney, R. A., Rubinstein, M. & Gozes, I., 1 Jul 2022, In: Biological Psychiatry. 92, 1, p. 81-95 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

37 Scopus citations

S-allylmercapto-N-acetylcysteine protects bone cells from oxidation and improves femur microarchitecture in healthy and diabetic mice

Abu-Kheit, R., Kotev-Emeth, S., Hiram-Bab, S., Gabet, Y. & Savion, N., Aug 2022, In: Experimental Biology and Medicine. 247, 16, p. 1489-1500 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

2021

Automated direct selective laser trabeculoplasty: First prospective clinical trial

Goldenfeld, M., Belkin, M., Dobkin-Bekman, M., Sacks, Z., Meirovitch, S. B., Geffen, N., Leshno, A. & Skaat, A., 2021, In: Translational Vision Science and Technology. 10, 3, p. 1-11 11 p., 5.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

Developmental alterations in firing properties of hippocampal CA1 inhibitory and excitatory neurons in a mouse model of Dravet syndrome

Almog, Y., Fadila, S., Brusel, M., Mavashov, A., Anderson, K. & Rubinstein, M., Jan 2021, In: Neurobiology of Disease. 148, 105209.

Research output: Contribution to journal › Article › peer-review

Open Access

23 Scopus citations

Extracellular proteolytic activation of Pseudomonas aeruginosa aminopeptidase (PaAP) and insight into the role of its noncatalytic N-terminal domain

Axelrad, I., Safrin, M., Cahan, R., Suh, S. J., Ohman, D. E. & Kessler, E., Jun 2021, In: PLoS ONE. 16, 6 June 2021, e0252970.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

Inhibition of Sema-3A Promotes Cell Migration, Axonal Growth, and Retinal Ganglion Cell Survival

Nitzan, A., Corredor-Sanchez, M., Galron, R., Nahary, L., Safrin, M., Bruzel, M., Moure, A., Bonet, R., Pérez, Y., Bujons, J., Vallejo-Yague, E., Sacks, H., Burnet, M., Alfonso, I., Messeguer, A., Benhar, I., Barzilai, A. & Solomon, A. S., 24 Nov 2021, In: Translational Vision Science and Technology. 10, 10, 16.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

Reprogramming of two induced pluripotent stem cell lines from a heterozygous GRIN2D developmental and epileptic encephalopathy (DEE) patient (BGUi011-A) and from a healthy family relative (BGUi012-A)

Rabinski, T., Sagiv, S. T., Hausman-Kedem, M., Fattal-Valevski, A., Rubinstein, M., Avraham, K. B. & Vatine, G. D., Mar 2021, In: Stem Cell Research. 51, 102178.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Retinal vascular signs as screening and prognostic factors for chronic kidney disease: A systematic review and meta-analysis of current evidence

Aronov, M., Allon, R., Stave, D., Belkin, M., Margalit, E., Fabian, I. D. & Rosenzweig, B., Jul 2021, In: Journal of Personalized Medicine. 11, 7, 665.

Research output: Contribution to journal › Article › peer-review

Open Access

18 Scopus citations

Transfer of SCN1A to the brain of adolescent mouse model of Dravet syndrome improves epileptic, motor, and behavioral manifestations

Mora-Jimenez, L., Valencia, M., Sanchez-Carpintero, R., Tønnesen, J., Fadila, S., Rubinstein, M., Gonzalez-Aparicio, M., Bunuales, M., Fernandez-Pierola, E., Nicolas, M. J., Puerta, E., Miguelez, C., Minguez, P. G., Lumbreras, S., Gonzalez-Aseguinolaza, G., Ricobaraza, A. & Hernandez-Alcoceba, R., 3 Sep 2021, In: Molecular Therapy Nucleic Acids. 25, p. 585-602 18 p.

Research output: Contribution to journal › Article › peer-review

Open Access

22 Scopus citations

2020

Ascorbic Acid Promotes Procollagen C-Proteinase Enhancer 1 Expression, Secretion, and Cell Membrane Localization

Gohar, O., Weiss, T., Wineman, E. & Kessler, E., 1 Jun 2020, In: Anatomical Record. 303, 6, p. 1670-1679 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Automated Diagnosis and Measurement of Strabismus in Children

Yehezkel, O., Belkin, M. & Wygnanski-Jaffe, T., May 2020, In: American Journal of Ophthalmology. 213, p. 226-234 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

32 Scopus citations

Convulsive seizures and some behavioral comorbidities are uncoupled in the Scn1a^A1783V Dravet syndrome mouse model

Fadila, S., Quinn, S., Turchetti Maia, A., Yakubovich, D., Ovadia, M., Anderson, K. L., Giladi, M. & Rubinstein, M., Oct 2020, In: Epilepsia. 61, 10, p. 2289-2300 12 p.

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Mild carotid stenosis creates gradual, progressive, lifelong brain, and eye damage: An experimental laboratory rat model

Tzameret, A., Piontkewitz, Y., Nitzan, A., Rudoler, N., Bruzel, M., Zilberstein, Y., Ziv, H., Pri-Chen, S. & Solomon, A. S., 1 Jul 2020, In: Journal of Comparative Neurology. 528, 10, p. 1672-1682 11 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Non-contact direct selective laser trabeculoplasty: Light propagation analysis

Sacks, Z. S., Dobkin-Bekman, M., Geffen, N., Goldenfeld, M. & Belkin, M., 1 Jun 2020, In: Biomedical Optics Express. 11, 6, p. 2889-2904 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Striatin Is Required for Hearing and Affects Inner Hair Cells and Ribbon Synapses

Nadar-Ponniah, P. T., Taiber, S., Caspi, M., Koffler-Brill, T., Dror, A. A., Siman-Tov, R., Rubinstein, M., Padmanabhan, K., Luxenburg, C., Lang, R. A., Avraham, K. B. & Rosin-Arbesfeld, R., 15 Jul 2020, In: Frontiers in Cell and Developmental Biology. 8, 615.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

2019

Analysis of procollagen c-proteinase enhancer-1/glycosaminoglycan binding sites and of the potential role of calcium ions in the interaction

Potthoff, J., Bojarski, K. K., Kohut, G., Lipska, A. G., Liwo, A., Kessler, E., Ricard-Blum, S. & Samsonov, S. A., 2 Oct 2019, In: International Journal of Molecular Sciences. 20, 20, 5021.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Scopus citations

COL1A1 C-propeptide mutations cause ER mislocalization of procollagen and impair C-terminal procollagen processing

Barnes, A. M., Ashok, A., Makareeva, E. N., Brusel, M., Cabral, W. A., Weis, M. A., Moali, C., Bettler, E., Eyre, D. R., Cassella, J. P., Leikin, S., Hulmes, D. J. S., Kessler, E. & Marini, J. C., 1 Sep 2019, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1865, 9, p. 2210-2223 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

22 Scopus citations

Evaluation of visual function in Royal College of Surgeon rats using a depth perception visual cliff test

Tzameret, A., Sher, I., Edelstain, V., Belkin, M., Kalter-Leibovici, O., Solomon, A. S. & Rotenstreich, Y., 2019, In: Visual Neuroscience. 36, e002.

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Investigating the neuroprotective effect of Copolymer-1 in acute primary angle closure – Interim report of a randomized placebo-controlled double-masked clinical trial

Fan, K. R. P., Baskaran, M., Nongpiur, M. E., Htoon, H. M., de Leon, J. M. S., Perera, S. A., Belkin, M. & Aung, T., 2019, In: Acta Ophthalmologica. 97, 6, p. e827-e832

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

In vivo, in vitro and in silico correlations of four de novo SCN1A missense mutations

Nissenkorn, A., Almog, Y., Adler, I., Safrin, M., Brusel, M., Marom, M., Bercovich, S., Yakubovich, D., Tzadok, M., Ben-Zeev, B. & Rubinstein, M., Feb 2019, In: PLoS ONE. 14, 2, e0211901.

Research output: Contribution to journal › Article › peer-review

Open Access

18 Scopus citations

Mitochondrial Regulation of the Hippocampal Firing Rate Set Point and Seizure Susceptibility

Styr, B., Gonen, N., Zarhin, D., Ruggiero, A., Atsmon, R., Gazit, N., Braun, G., Frere, S., Vertkin, I., Shapira, I., Harel, M., Heim, L. R., Katsenelson, M., Rechnitz, O., Fadila, S., Derdikman, D., Rubinstein, M., Geiger, T., Ruppin, E. & Slutsky, I., 5 Jun 2019, In: Neuron. 102, 5, p. 1009-1024.e8

Research output: Contribution to journal › Article › peer-review

Open Access

83 Scopus citations

Randomized Controlled Phase 2a Study of RPh201 in Previous Nonarteritic Anterior Ischemic Optic Neuropathy

Rath, E. Z., Hazan, Z., Adamsky, K., Solomon, A., Segal, Z. I. & Levin, L. A., 1 Sep 2019, In: Journal of Neuro-Ophthalmology. 39, 3, p. 291-298 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

16 Scopus citations

S-allylmercapro-N-acetylcysteine attenuates the oxidation-induced lens opacification and retinal pigment epithelial cell death in vitro

Savion, N., Dahamshi, S., Morein, M. & Kotev-Emeth, S., 1 Jan 2019, In: Antioxidants. 8, 1, 25.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Spatial visual function in anomalous trichromats: Is less more?

Doron, R., Sterkin, A., Fried, M., Yehezkel, O., Lev, M., Belkin, M., Rosner, M., Solomon, A. S., Mandel, Y. & Polat, U., Jan 2019, In: PLoS ONE. 14, 1, e0209662.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

2018

Association of rare missense variants in the second intracellular loop of Na v 1.7 sodium channels with familial autism

Rubinstein, M., Patowary, A., Stanaway, I. B., McCord, E., Nesbitt, R. R., Archer, M., Scheuer, T., Nickerson, D., Raskind, W. H., Wijsman, E. M., Bernier, R., Catterall, W. A. & Brkanac, Z., 1 Feb 2018, In: Molecular Psychiatry. 23, 2, p. 231-239 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

27 Scopus citations

Effect of stimulus intensity and visual field location on rod-and cone-mediated pupil response to focal light stimuli

Yahia, S. H., Hamburg, A., Sher, I., Ner, D. B., Yassin, S., Chibel, R., Mimouni, M., Derazne, E., Belkin, M. & Rotenstreich, Y., Dec 2018, In: Investigative Ophthalmology and Visual Science. 59, 15, p. 6027-6035 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Intraocular pressure remote photonic biomonitoring based on temporally encoded external sound wave stimulation

Bennett, A., Beiderman, Y., Agdarov, S., Beiderman, Y., Ozana, N., Belkin, M. & Zalevsky, Z., 1 Nov 2018, In: Journal of Biomedical Optics. 23, 11, 117001.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

Role of heterotrimeric G proteins in platelet activation and clot formation in platelets treated with integrin αIIbβ3 inhibitor

Budnik, I., Shenkman, B., Hauschner, H., Zilinsky, I. & Savion, N., 3 Apr 2018, In: Platelets. 29, 3, p. 265-269 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

S-allylmercapto-N-acetylcysteine protects against oxidative stress and extends lifespan in Caenorhabditis elegans

Savion, N., Levine, A., Kotev-Emeth, S., Abu-Shach, U. B. & Broday, L., Mar 2018, In: PLoS ONE. 13, 3, e0194780.

Research output: Contribution to journal › Article › peer-review

Open Access

13 Scopus citations

2017

A minimally invasive adjustable-depth blunt injector for delivery of pharmaceuticals into the posterior pole

Rotenstreich, Y., Tzameret, A., Kalish, S. E., Bubis, E., Belkin, M., Moroz, I., Rosner, M., Levy, I., Margel, S. & Sher, I., 1 May 2017, In: Acta Ophthalmologica. 95, 3, p. e197-e205

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

Data comparing the plasma levels of procollagen C-proteinase enhancer 1 (PCPE-1) in healthy individuals and liver fibrosis patients

Hassoun, E., Safrin, M., Wineman, E., Weiss, P. & Kessler, E., Oct 2017, In: Data in Brief. 14, p. 777-781 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

Lithium reduces the span of G protein-activated K⁺ (GIRK) channel inhibition in hippocampal neurons

Dascal, N. & Rubinstein, M., Nov 2017, In: Bipolar Disorders. 19, 7, p. 568-574 7 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Long-Term Safety of Transplanting Human Bone Marrow Stromal Cells into the Extravascular Spaces of the Choroid of Rabbits

Tzameret, A., Kalish, S. E., Sher, I., Twito, L., Meir, A., Levy, I., Margel, S., Moroz, I., Rosner, M., Treves, A. J., Nagler, A., Belkin, M. & Rotenstreich, Y., 18 Jun 2017, In: Stem Cells International. 2017, 4061975.

Research output: Contribution to journal › Article › peer-review

Open Access